Results 111 to 120 of about 5,494,240 (282)

Pressure‐Assisted Drug Delivery Using High‐Pressure Balloon Platform Improves Vascular Drug Penetration and Anti‐Restenotic Effects

Advanced Healthcare Materials, EarlyView.
A dual‐layer high‐pressure drug‐coated balloon (HP@DCB) increased balloon‐wall contact and promoted deeper paclitaxel (PTX) penetration than a conventional noncompliant DCB. In in vivo study, HP@DCB treatment improved luminal patency and reduced neointimal hyperplasia, supporting pressure‐assisted drug delivery as a promising strategy for enhancing the
Seung Jin Eo, So Yun Lim, Dong‐Sung Won, Ji Won Kim, Yubeen Park, Song Hee Kim, Hyemin Lee, Jung‐Min Ahn, Jun‐Kyu Park, Do‐Yoon Kang, Jung‐Hoon Park   +10 more
wiley   +1 more source

Viscoelastic materials are most energy efficient when loaded and unloaded at equal rates

Journal of The Royal Society Interface
Biological springs can be used in nature for energy conservation and ultra-fast motion. The loading and unloading rates of elastic materials can play an important role in determining how the properties of these springs affect movements. We investigate the mechanical energy efficiency of biological springs (American bullfrog plantaris tendons and guinea
Lucien Tsai, Paco Navarro, Siqi Wu, Taylor Levinson, Elizabeth Mendoza, M. Janneke Schwaner, Monica A. Daley, Emanuel Azizi, Mark Ilton   +8 more
openaire   +5 more sources

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

Can Elastomers Combine Stiffness, Toughness and Fatigue Resistance?

Advanced Materials, EarlyView.
This review studies how the molecular and macroscopic architecture of elastomers influence their mechanical properties including: stiffness, stretchability, toughness, fatigue resistance, and damping behavior. By linking the structure to performance, it proposes design principles for advanced elastomeric systems that combine mechanical properties ...
Eva Baur, Esther Amstad
wiley   +1 more source

Descriptors to Dynamics: A Materials and Device Perspective on in‐Materio Physical Reservoir Computing for Neuromorphic Edge Intelligence

Advanced Materials, EarlyView.
Intrinsic material dynamics are harnessed as computational resources for neuromorphic in‐materio physical reservoir computing. Defects, ionic motion, interfaces, percolation, geometry, and biasing shape transient states that provide fading memory, nonlinearity, and high‐dimensional projection for simple readout. A descriptor‐to‐dynamics framework links
Kshitij RB Singh, Alif Syafiq Kamarol Zaman, Muzhen Xu, Yuki Usami, Saptarshi Das, Hirofumi Tanaka   +5 more
wiley   +1 more source

Non Linear Strain Rate Dependency and Unloading Behavior of Semi-Crystalline Polymers

, 2007
The classical viscoelastic constitutive equations do not simulate correctly the mechanical behavior of semi crystalline polymers, particularly in the case of the strain rate jumping or unloading to zero stress after tensile testing. The main experimental
N. Bahlouli, V. Oshmyan, Y. Rémond, K. Hizoum, S. Ahzi, S. Patlazhan   +5 more
core   +1 more source

Fabrication of Aligned Polycaprolactone Nanofibrillar Bundles to Control Cell‐Mediated Collagen Deposition in Engineered Cartilage

Advanced Materials, EarlyView.
Melt electrofibrillation (MEF) enables the fabrication of nanofibrillar PCL scaffolds with defined architectures that guide cellular alignment and retention during cartilage tissue engineering. Unlike conventional melt electrowriting, MEF consistently directs collagen type II‐rich extracellular matrix organization, providing a tunable platform to ...
Alba Pueyo Moliner, Lennard Spauwen, James L. Martin Robinson, Ángela García Grech, Isabelle Martinier, Sara Grasselli, Aylin Kara Özenler, Matthias Ryma, Jürgen Groll, Mylène de Ruijter, Jos Malda   +10 more
wiley   +1 more source

RESPIRATORY MUSCLE UNLOADING AND ENDURANCE EXERCISE PERFORMANCE [PDF]

, 1992
Ventilatory demand increases throughout endurance exercise. It was hypothesised that if the normal loads on the respiratory muscles contribute to the limitation of endurance exercise, then a reduction of these loads (resistive unloading) should improve ...
Krishnan, S. Bharath
core  

Seamless Mechanical Programming Through Hybrid Epoxy–Acrylate Printing for Soft–Rigid Robots

Advanced Materials, EarlyView.
Hybrid epoxy‐acrylate printing enables seamless fabrication of soft–rigid robotic systems with covalently integrated interfaces and functionally graded mechanics. Grayscale exposure expands the accessible material space, enabling spatially programmed actuation through patterned stiffness while revealing the mechanics and durability of continuously ...
David C. Bershadsky, Franz A. Stolpen, Zachariah A. Page, Lillian Chin   +3 more
wiley   +1 more source

Mesoscopic fracturing mechanism in sandstone: Influence of confining pressure unloading rate

Energy Exploration & Exploitation
The rock mass damage and failure induced by underground coal resource exploitation are strongly influenced by the confining pressure unloading (CPU) rate. However, the impact of CPU rate as a sole variable remains inadequately understood. This study utilizes discrete element numerical tests to explore the influence of CPU rate on the mesoscopic ...
Jian Zhang, Liangliang Guo, Dekang Zhao, Kun Tu, Wenping Mu   +4 more
openaire   +2 more sources