Results 121 to 130 of about 5,494,240 (282)

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

Mesoscopic contact and structural evolution characteristics in sandstone during confining pressure unloading

Meitan kexue jishu
Due to limitations of current physical testing equipment, it is difficult to track the internal contact characteristics and motion information of specimens.
Jian ZHANG, Yifan ZENG, Qiang WU, Liangliang GUO, Qin LIU   +4 more
doaj   +1 more source

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

Unloading Empty Shells

, 2011
Group of men unloading empty ammunition shells from a cart.Caption: Unloading empty shells for refilling Constitutionialistas.Photograph taken probably 1910 ...
Unknown
core   +1 more source

Millifluidic Synthesis of Core–Shell Resonators For Tunable Sonic BandGaps in Acoustic Metamaterials

Advanced Materials Interfaces, EarlyView.
Millimeter‐scale core–shell acoustic resonators are fabricated by a gravity‐assisted dripping approach and incorporated into epoxy composites at controlled volume fractions. The resulting alumina–core resonator composites show tunable low‐frequency acoustic attenuation, demonstrating a scalable route for integrating locally resonant metamaterial units ...
Colton Steiner, Xiaohui Shen, Bianka Pajo, Chin‐Teh Sun, Jeffrey P. Youngblood, Carlos Martinez   +5 more
wiley   +1 more source

A new loading-unloading experimental method for simulating the change of mining-induced stress

, 2019
Based on a self-developed triaxial seepage device, a new loading and unloading experimental method is proposed in this paper to eliminate sample variations.
Jiang, Changbao, Duan, Minke, Liu, Xiaodong, Yu, Huan, Li, Minghui   +4 more
core   +1 more source

Reducing Interfacial Separation Force in High‐Speed Constrained‐Surface Projection Stereolithography Using a Dual‐Modulus Silicone Release Film

Advanced Materials Interfaces, EarlyView.
A dual‐modulus silicone release film creates distributed stress concentrations at high‐/low‐modulus boundaries, triggering multi‐site crack initiation and rapid interfacial detachment. The architecture lowers the peak separation force by 97.6%, shortens detachment time, and enables stable continuous projection stereolithography at 720 mm h−1, offering ...
Xiaogang Li, Xiaoqing Kang, Hong Xiao, Yugang Duan   +3 more
wiley   +1 more source

Experimental investigation of the acoustic emission characteristics and failure modes of triaxial unloading confining pressure in deep limestone

工程科学学报
To clarify the mechanical destabilization and fracturing characteristics of deep limestone subjected to high-confining-pressure unloading, a series of triaxial tests with synchronous acoustic-emission (AE) monitoring was performed on standard limestone ...
Chaoqun CHU, Xingjia BAO, Shunchuan WU, Hejia CUI, Guang ZHANG   +4 more
doaj   +1 more source

Study on the emptying time of grain harvest hopper [PDF]

Agricultural Science and Technology, 2017
. When unloading grain harvester hoppers at a standstill the emptying time has an effect on the grain harvester performance. A study has been conducted on the actual emptying time of harvester grain hoppers on various farms in Bulgaria and the actual ...
K. Trendafilov , N. Delchev, B. Kolev, G. Tihanov   +3 more
doaj  

Two‐Way Shape Memory Polymer Composite Gripper for Adaptive Robotic Applications

Advanced Materials Technologies, EarlyView.
A two‐way shape memory polymer (SMP) composite is developed with intrinsic shape‐changing capability driven solely by temperature, eliminating external actuation loads. Embedding the SMP in a low‐stiffness elastomeric matrix enabled reversible transformations during heating and cooling cycles.
Aamna Hameed, Kamran Ahmed Khan
wiley   +1 more source