Results 31 to 40 of about 2,845,268 (289)

Protein engineering with unnatural amino acids

Current Opinion in Structural Biology, 2013
Protein engineering has become an extensively used tool in many fields, allowing us to probe protein function, characterize proteins using a range of biophysical techniques, chemically modify proteins and improve protein function for medical and industrial applications.
Zhang, William, Jackson, Colin, Otting, Gottfried   +2 more
openaire   +3 more sources

Genetic Code Expansion of Vibrio natriegens

Frontiers in Bioengineering and Biotechnology, 2021
Escherichia coli has been considered as the most used model bacteria in the majority of studies for several decades. However, a new, faster chassis for synthetic biology is emerging in the form of the fast-growing gram-negative bacterium Vibrio ...
Eden Ozer, Lital Alfonta
doaj   +1 more source

Electrochemical Synthesis of Unnatural Amino Acids Embedding 5- and 6-Membered Heteroaromatics [PDF]

, 2023
Using a commercially available potentiostat, the electrochemical synthesis of unnatural amino acids bearing heteroaromatics on the lateral chain has been accomplished.
Paolo, Ronchi, Elena , Bombonato, Valerio, Fasano, Daniel, Pecorari, Massimo, Marcaccio, Luca, Fornasari   +5 more
core   +2 more sources

Efficient Incorporation of Unnatural Amino Acids into Proteins with a Robust Cell-Free System

Methods and Protocols, 2019
Unnatural proteins are crucial biomacromolecules and have been widely applied in fundamental science, novel biopolymer materials, enzymes, and therapeutics.
Wei Gao, Ning Bu, Yuan Lu
doaj   +1 more source

Nickel-Catalyzed Cross-Coupling of Amino-Acid-Derived Alkylzinc Reagents with Alkyl Bromides/Chlorides: Access to Diverse Unnatural Amino Acids

, 2021
Unnatural α-amino acids are important synthetic targets in the field of peptide science. Herein we report an efficient, versatile, and straightforward strategy for the synthesis of homophenylalanine derivatives via the nickel-catalyzed Csp3–Csp3 cross ...
Zhen Wang (72451), Jie Tong (750316), Chun-Yang He (1843288), Jie Tong, An-Jun Wang (4685575), Ze Wang (132986), Ze Wang, Chun-Yang He, Ming-Jian Ma (11879678), Liang Zhao, Fei-Hu Gou (7408499), Haoyang Wang, Zhen Wang, Haoyang Wang (2090752), Liang Zhao (94728), Fei-Hu Gou, An-Jun Wang, Ming-Jian Ma   +17 more
core   +1 more source

Visualizing HCV Core Protein via Fluorescent Unnatural Amino Acid Incorporation

Proceedings, 2020
Introduction: Unnatural amino acids (UAAs) share the same basic structure as proteinogenic amino acids. However, UAAs permit additional functions and applications to proteins due to their different side chains.
Leah Jane Fitzgerald Curnew, Kate McNicholas, Bridgette Green, Jackie Barry, Hannah L Wallace, Lingyan Wang, Cassandra Davidson, John P Pezacki, Rodney S Russell   +8 more
doaj   +1 more source

Amino acid uptake in Arabidopsis [PDF]

, 2008
Nitrogen (N) is essential for all living organisms and is considered to be the limiting factor for plant growth in many ecosystems. Although generally believed to rely on mineral N to fulfill their N needs, plants have also been found to access organic N
Svennerstam, Henrik
core   +1 more source

Development of natural and unnatural amino acid delivery systems against hookworm infection

Precision Nanomedicine, 2020
Peptide-based vaccines consist of short antigen fragments derived from a specific pathogen. Alone, these peptide fragments are poorly or non-immunogenic; however, when incorporated into a proper delivery system, they can trigger strong immune responses.
Stacey Bartlett, Mariusz Skwarczynski, Xin Xie, Istvan Toth, Alex Loukas, Ramon M Eichenberger   +5 more
doaj   +1 more source

Diel rhythmicity in amino acid uptake by Prochlorococcus [PDF]

, 2008
The marine cyanobacterium Prochlorococcus, the most abundant phototrophic organism on Earth, numerically dominates the phytoplankton in nitrogen (N)-depleted oceanic gyres.
Terry, Matthew J, Garczarek, Laurence, Tarran, Glen A, Mary, Isabelle, Burkill, Peter H, Scanlan, David J, Kolowrat, Christian, Zubkov, MV, Zubkov, Mikhail V, Terry, MJ, Tarran, Glen A., Scanlan, David J., Scanlan, DJ, Burkill, Peter H., Tarran, GA, Terry, Matthew J., Burkill, PH, Zubkov, Mikhail V., Kolowrat, CK, Mary, I, Garczarek, LG   +20 more
core   +1 more source

Root phloem-specific expression of the plasma membrane amino acid proton co-transporter AAP3 [PDF]

, 2004
Amino acids are regarded as the nitrogen ‘currency’ of plants. Amino acids can be taken up from the soil directly or synthesized from inorganic nitrogen, and then circulated in the plant via phloem and xylem.
Sakiko Okumoto, Leister, D., Frommer, Wolf B., Wolf B. Frommer, Okumoto, Sakiko, FISCHER, Wolf N, Stierhof, York Dieter, Frommer, W. B., Stierhof, Y., Stierhof, Y.-D., Fischer, W., Wolfgang Koch, Koch, W., FROMMER, Wolf B, Mechthild Tegeder, Fischer, Wolf N., Leister, Dario, Wolf N. Fischer, Koch, Wolfgang, Okumoto, S., Tegeder, Mechthild, Dario Leister, Tegeder, M., Biehl, A., York Dieter Stierhof, Alexander Biehl, Biehl, Alexander, Fischer, W. N., Frommer, W.   +28 more
core   +2 more sources