Results 181 to 190 of about 402 (208)

Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome

International Journal of Cancer, EarlyView.
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin, Dong Keon Kim, Yoojeong Seo, Hyeon Hee Lee, Jihye Park, Soo Jung Park, Jae Jun Park, Jae Hee Cheon, Jongwon Oh, Sanghoo Lee, Tae Il Kim   +10 more
wiley   +1 more source

Advances in Immunological Combination Therapy for Colorectal Cancer

iMetaMed, EarlyView.
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu, Rongbo Wen, Tianshuai Zhang, Fuao Cao, Xiaoming Zhu, Liqiang Hao, Wei Zhang, Guanyu Yu   +7 more
wiley   +1 more source

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

iMetaOmics, EarlyView.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang, Jianhong Tian, Wenyan Zhao, Siqin Zhang, Lixuan Xiang, Meiqing Yang, Lu Liu, Yazhou Huang, Ningyun Zhang, Lei Sun, Peng Xie, Nanyu Kuang, Hong Zhou, Chengfeng Qiu, Jun Yan, Xiaocheng Jiang, Qiang Tu, Yun Wang, Haoliang Hu, Youming Zhang   +19 more
wiley   +1 more source

Surfactant Enhanced Bioremediation of Saline Diesel Contaminated Water by a Novel Bacterial Halophilic Consortium

Journal of Surfactants and Detergents, EarlyView.
ABSTRACT The use of microorganisms is an evolving method for the degradation of hydrocarbon contaminants. In this aim, halophilic hydrocarbon degrading bacteria were isolated from oil contaminated soil in Tunisia. A lipopeptide biosurfactant produced by Bacillus subtilis SPB1 was tested to increase diesel biodegradation along with co‐inoculation with ...
Inès Mnif, Dhouha Ghribi
wiley   +1 more source

Prevalence and trends of cervical cancer screening among women in Fiji from 2014 to 2018. [PDF]

Heliyon
Kunatoga A, Mohammadnezhad M, Khan S, Naeem P, Nusair P.   +4 more
europepmc   +1 more source

Environment and diet shape the geography-specific <i>Drosophila melanogaster</i> microbiota composition. [PDF]

Appl Environ Microbiol
Gale JT, Kreutz R, Gottfredson Morgan SJ, Davis EK, Hough C, Cisneros Cancino WA, Burnside B, Barney R, Hunsaker R, Tanner Hoyt A, Cluff A, Nosker M, Sefcik C, Beales E, Beltz JK, Frandsen PB, Schmidt P, Chaston JM.   +17 more
europepmc   +1 more source

Targeted Intervention Strategies for Maternal-Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model. [PDF]

Adv Sci (Weinh)
Shen H, Ma X, Zhang L, Li H, Zheng J, Wu S, Zuo K, Yin Y, Wang J, Tan B.   +9 more
europepmc   +1 more source

Multianalytical investigation reveals psychotropic substances in a ptolemaic Egyptian vase. [PDF]

Sci Rep
Tanasi D, van Oppen de Ruiter BF, Florian F, Pavlovic R, Chiesa LM, Fochi I, Stani C, Vaccari L, Chaput D, Samorini G, Pallavicini A, Semeraro S, Gaetano AS, Licen S, Barbieri P, Greco E.   +15 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

The impact of alcohol taxation changes on unrecorded alcohol consumption: A review and recommendations

International Journal of Drug Policy, 2022
Jürgen Rehm, Maria Neufeld, Bundit Sornpaisarn   +2 more
exaly