A genome-wide association study for clinical mastitis in first parity US Holstein cows using single-step approach and genomic matrix re-weighting procedure. [PDF]
Tiezzi F +4 more
europepmc +1 more source
Loss, persistence and reversal of phenotypic traits
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni +4 more
wiley +1 more source
Status and future of recombinant adeno‐associated virus vector manufacturing
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
Cryptic disease in a cat with painful and swollen hocks: an exercise in diagnostic reasoning and clinical decision-making. [PDF]
Tisdall PL, Martin P, Malik R.
europepmc +1 more source
Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
Traceability, reproducibility and wiki-exploration for "à-la-carte" reconstructions of genome-scale metabolic models. [PDF]
Aite M +14 more
europepmc +1 more source
Comparative Study of Free and Total Fatty Acids of Spreadable Cheeses by Mass Spectrometry Methods
This study focuses on the determination of FFAs in spreadable cheeses and alternatives using a fast Liquid Chromatography‐High Resolution Mass Spectrometry method. A Gas Chromatography‐Mass Spectrometry method was used to determine the composition (%) of total FAs in the same samples.
Christiana Mantzourani +6 more
wiley +1 more source
New Penicillium and Talaromyces species from honey, pollen and nests of stingless bees. [PDF]
Barbosa RN +6 more
europepmc +1 more source
The Role of Iron‐Hyponitrite Intermediates in Biology and Insights From Synthetic Model Complexes
Despite the difference in active site architecture, NO reduction by different NOR enzymes is expected to be linked by a common intermediate: hyponitrite (N2O22−). However, experimentally, very little is known about the coordination chemistry of iron with hyponitrite and the expected Fe‐hyponitrite intermediates.
Michael O. Lengel, Nicolai Lehnert
wiley +1 more source
A phylogenetic analysis of Greek isolates of Aspergillus species based on morphology and nuclear and mitochondrial gene sequences. [PDF]
Krimitzas A +4 more
europepmc +1 more source

