Patient Preferences in Neuromuscular Diseases: Insights for Future Drug Development
ABSTRACT Incorporating patient preferences into drug development is crucial, particularly, for rare diseases with significant unmet needs. This study used Best‐Worst Scaling type 2 (BWS‐2) to explore benefit–risk trade‐offs for patients and caregivers in two rare neuromuscular diseases (NMDs), myotonic dystrophy type 1 (DM1), and mitochondrial myopathy
Aura Cecilia Jimenez‐Moreno +10 more
wiley +1 more source
Bridging spatial and temporal surface pressure dynamics for gust aerodynamic modeling. [PDF]
Chen D, Liang A, Sun B, Rival DE, Fan D.
europepmc +1 more source
The Rhythmic and the Metronomic: On Charlie Chaplin's Gait
Critical Quarterly, EarlyView.
Matthew Beaumont
wiley +1 more source
Large Eddy Simulations of the Atmospheric Boundary Layer Over Satellite‐Sensed Sea Ice Maps
Abstract Surface heterogeneity in the marginal ice zone (MIZ) causes multiscale secondary atmospheric circulations that are challenging to model or observe. The absence or inadequate representation of these circulations in ocean‐atmosphere exchange schemes in climate models is partially responsible for the underestimation of Arctic sea ice loss ...
Joseph Fogarty +5 more
wiley +1 more source
Bio-Inspired Blade Cascades: Numerical Predictions Versus Experimental Measurements. [PDF]
Totu AG, Crunțeanu DE, Isvoranu D.
europepmc +1 more source
Passive unsteady aerodynamic force of a swallowtail butterfly
identifier:oai:t2r2.star.titech.ac.jp ...
openaire
From Lotic to Lentic: SWOT Characterizes Seasonal Hydrodynamics in the Lake‐River Continuum
Abstract The interface between rivers and lakes forms a unique hydraulic continuum, in which lotic and lentic regimes dynamically interact and transition between each other. A common expression of this lake‐river continuum (LARIC) is reservoir backwater, where water surface gradually rises from the reservoir pool upstream to the free‐flowing river ...
Xinchen He +7 more
wiley +1 more source
Optimizing avian flight dynamics with a synergetic bio-inspired and machine learning approach. [PDF]
Khalid W +3 more
europepmc +1 more source
Abstract We present the first in situ observations of the full turbulence tensor of free convection under lake ice, obtained using an original method based on a set of two synchronized acoustic Doppler profilers to measure all six turbulent stress components.
G. B. Kirillin +2 more
wiley +1 more source
Hybrid LQR-H<sub>2</sub> Control of a Kestrel-Based Ornithopter with a Nature-Inspired Flow Control Device for Gust Mitigation. [PDF]
Hussain S, Hennache A, Abbasi N, Xu D.
europepmc +1 more source

