PLoS Neglected Tropical Diseases, 2022 The parasite Trypanosoma brucei grows as bloodstream forms in mammalian hosts, and as procyclic forms in tsetse flies. In trypanosomes, gene expression regulation depends heavily on post-transcriptional mechanisms.
Tania Bishola Tshitenge +3 more
doaj +1 more source
Pathway prediction by bioinformatic analysis of the untranslated regions of the CFTR mRNA [PDF]
, 2009 Mining the information contained within the genetic code in untranslated regions has proven difficult because of the ambiguity of microRNA and protein binding sites.
Spence, Jean
core +1 more source
Spatial preferences of microRNA targets in 3' untranslated regions
BMC Genomics, 2007 Background MicroRNAs are an important class of regulatory RNAs which repress animal genes by preferentially interacting with complementary sequence motifs in the 3' untranslated region (UTR) of target mRNAs.
Ohler Uwe, Majoros William H
doaj +1 more source
Highly accessible AU-rich regions in 3' untranslated regions are hotspots for binding of regulatory factors. [PDF]
PLoS Computational Biology, 2017 Post-transcriptional regulation is regarded as one of the major processes involved in the regulation of gene expression. It is mainly performed by RNA binding proteins and microRNAs, which target RNAs and typically affect their stability.
Mireya Plass +2 more
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Genome Biology, 2022 RNA processing, including splicing and alternative polyadenylation, is crucial to gene function and regulation, but methods to detect RNA processing from single-cell RNA sequencing data are limited by reliance on pre-existing annotations, peak calling ...
Elisabeth Meyer +3 more
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The ODC 3′-Untranslated Region and 5′-Untranslated Region Contain cis-Regulatory Elements: Implications for Carcinogenesis [PDF]
Medical Sciences, 2017 It has been hypothesized that both the 3′-untranslated region (3′UTR) and the 5′-untranslated region (5′UTR) of the ornithine decarboxylase (ODC) mRNA influence the expression of the ODC protein. Here, we use luciferase expression constructs to examine the influence of both UTRs in keratinocyte derived cell lines. The ODC 5′UTR or 3′UTR was cloned into
Shannon Nowotarski, Lisa Shantz
openaire +3 more sources
Regulatory RNAs: Have mRNA Untranslated Regions Joined the Party.
PLoS Medicine, 2008 Thomas Hughes and Pamela Jones discuss the implications of a new study on the 5' non-coding region of vascular endothelial growth factor mRNA and its influence on gene expression.
Thomas A Hughes, Pamela F Jones
doaj +1 more source
Lengths of the coding and untranslated regions of each of the 10 genomic segments of virus XZ0906. [PDF]
, 2014 Lengths of the coding and untranslated regions of each of the 10 genomic segments of virus XZ0906.
Zhiyu Wang (282312) +6 more
core +1 more source
Transcription factor binding motif enrichment in the 5′ untranslated regions (UTRs) of genes overexpressed in specific tissues. [PDF]
, 2014 Transcription factor binding motif enrichment in the 5′ untranslated regions (UTRs) of genes overexpressed in specific tissues.
Douglas P. Jasmer (51913) +2 more
core +1 more source
Lengths of the coding and untranslated regions of each of the 10 genomic segments of RpMRV-YN2012. [PDF]
, 2015 Lengths of the coding and untranslated regions of each of the 10 genomic segments of RpMRV-YN2012.
Qing Tang (167623) +10 more
core +1 more source