Results 41 to 50 of about 455 (134)

Demanding, but definitely worth it! A mixed‐methods study on parental experiences with early‐life oral immunotherapy

Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
Abstract Background Early oral immunotherapy for food allergy (<3 years of age; eOIT) shows promise for inducing sustained unresponsiveness. However, concerns about its feasibility remain. Parental experiences with eOIT have not yet been studied, but understanding these is crucial for improving its clinical implications.
Lieke J. C. Barten, Kim Kamphorst, Jamila de Jong, Annelies van der Kolk, Joyce Faber, Johan Garssen, Ted Klok   +6 more
wiley   +1 more source

Management of Pediatric Chronic Spontaneous Urticaria: A Review of Current Evidence and Guidelines

Journal of Asthma and Allergy, 2021
Jasmine Chang,1 Leila Cattelan,2 Moshe Ben-Shoshan,3 Michelle Le,2 Elena Netchiporouk2 1Department of Medicine, McGill University, Montreal, Quebec, Canada; 2Division of Dermatology, McGill University Health Centre, Montreal, Quebec, Canada; 3Division of
Chang J, Cattelan L, Ben-Shoshan M, Le M, Netchiporouk E   +4 more
doaj  

Codfish Oral Immunotherapy in Children Aged 2–10: Randomized Placebo‐Controlled Study

Allergy, Volume 81, Issue 5, Page 1799-1812, May 2026.
Codfish OIT significantly increased desensitization in children with fish allergy (43% vs. 11% placebo, p = 0.003), with 69% achieving 10‐fold threshold increases versus 26% in placebo (p = 0.0003). Sustained unresponsiveness remained limited (23% vs. 9%, p = 0.332). Treatment demonstrated acceptable safety with predominantly mild reactions and reduced
Agnes Sze‐yin Leung, Yanjun Gu, Ann Wing‐shan Au, Rosetta Tsz‐ching Leung, Vanessa Hiu‐tung Tang, Kin Yi Fung, Janice Min Li, Christine Yee‐yan Wai, Ting Fan Leung, Gary Wing‐kin Wong   +9 more
wiley   +1 more source

Omalizumab Therapy Results in Defined Behavioural Changes and Improvements in Quality of Life in Solar Urticaria

Photodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 3, May 2026.
ABSTRACT Background Solar urticaria is a rare photodermatosis in which exquisite photosensitivity can require extreme behavioural adaptations, resulting in a substantial impact on quality of life (QoL). Omalizumab therapy has been demonstrated to improve several clinical outcome measures, but the impact on behavioural measures is poorly understood. Our
Donna Parkin, Elizabeth J. Marjanovic, Mark D. Farrar, Lesley E. Rhodes, Kirsty J. Rutter   +4 more
wiley   +1 more source

A Comparative, Three-Arm, Randomized Clinical Trial to Evaluate the Effectiveness and Tolerability of Bilastine vs Fexofenadine vs Levocetirizine at the Standard Dose and Bilastine vs Fexofenadine at Higher Than the Standard Dose (Up-Dosing) vs Levocetirizine and Hydroxyzine (in Combination) in Patients with Chronic Spontaneous Urticaria

Clinical, Cosmetic and Investigational Dermatology, 2022
Bela Shah,1 Dhiraj Dhoot,2 Ankita Choudhary,1 Neha Jangid,1 Deval Mistry,1 Shikha Shah,1 Shruti Kamat,1 Hanmant Barkate3 1Department of Dermatology, Venereology and Leprosy, B.J.Medical College, Civil Hospital, Ahmedabad, India; 2DGM, Department of ...
Shah B, Dhoot D, Choudhary A, Jangid N, Mistry D, Shah S, Kamat S, Barkate H   +7 more
doaj  

Escape From Synthetic T Cell Activator Tebentafusp by Genomic HLA Loss: A Case Report

HLA, Volume 107, Issue 5, May 2026.
ABSTRACT Tebentafusp, a T‐cell receptor‐bispecific molecule targeting glycoprotein 100‐derived peptide presented by HLA class I molecule and CD3, is standard of care for patients with unresectable or metastatic uveal melanoma who are positive for HLA‐A*02:01. Mechanisms of resistance to tebentafusp are unknown. We report a patient with metastatic uveal
Halime Kalkavan, Andreas Heinold, Siyang Liu, Gaurav M. Borse, Falko M. Heinemann, Thomas Dertnig, Jörg Hense, Marc Ingenwerth, Fung‐Yi Cheung, Georgia Antonopoulou, Ina Pretzell, Katharina Fleischhauer, Nikolaos E. Bechrakis, Martin Schuler   +13 more
wiley   +1 more source

Prolonged IL‐33 Exposure Switches the Secreted Mast Cell Cytokine Profile From Pro‐Inflammatory to Pro‐Tolerant

Allergy, Volume 81, Issue 3, Page 720-733, March 2026.
This study investigates the effect of IL‐33 and Hymenoptera venom on mast cell cytokine profiles under venom immunotherapy (VIT)‐like conditions. Our in vitro model of VIT‐like mast cell stimulation demonstrates a modulatory effect of IL‐33 on the secreted mast cell cytokine profile.
Andrea R. Teufelberger, Carolin Költgen, Magda Babina, Peter Wolf   +3 more
wiley   +1 more source

Cardiac safety of second‐generation H₁‐antihistamines when updosed in chronic spontaneous urticaria

Clinical & Experimental Allergy, 2019
AbstractThe symptoms of chronic urticaria, be it chronic spontaneous urticaria (CSU) or chronic inducible urticaria (CindU), are mediated primarily by the actions of histamine on H1 receptors located on endothelial cells (the weal) and on sensory nerves (neurogenic flare and pruritus).
Mauro Cataldi, Marcus Maurer, Maurizio Taglialatela, Martin K. Church   +3 more
openaire   +3 more sources

Steady steps to desensitization: Low‐increment OIT for pediatric wheat allergy

Pediatric Allergy and Immunology, Volume 37, Issue 7, July 2026.
Nikolaos A. Kitsioulis, Paraskevi Xepapadaki, Emmanouil Manousakis, Styliani Taka, Nikolaos G. Papadopoulos   +4 more
wiley   +1 more source

Simulating the impact of an educational and digital approach using patient journey modelling to overcome practical challenges in the management of chronic spontaneous urticaria in Germany

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 3, Page 338-346, March 2026.
Summary Background and Objective Despite the availability of guidelines and effective escalation therapies, chronic spontaneous urticaria (CSU) is often inadequately treated in Germany. Implementation science can help to transfer evidence‐based care into practice.
Ralph von Kiedrowski, Mark Berneburg, Mona Biermann, Hanna Bonnekoh, Michael Fritz, Max Tischler, Martin Metz, Sebastian Volc, Nicola Wagner, Alexander Zink, Petra Nathan   +10 more
wiley   +1 more source