Results 51 to 60 of about 578 (168)

Clinical efficacy and safety of secukinumab for psoriasis in a real-world setting in Turkey

open access: yes, 2020
Objectives The aim of this study was to examine the real-life efficacy and safety of secukinumab for psoriasis (PsO) along with the factors that could have an effect on clinical response.
Fatma Aslı Hapa, Fatma Elif Yıldırım
core   +1 more source

Fel d 1‐Expressing Plant‐Derived Bioparticle: A Novel Treatment for Cat Allergy

open access: yesAllergy, Volume 81, Issue 6, Page 2156-2171, June 2026.
This study investigates the allergenicity and immunogenicity profile of a novel plant‐derived Fel d 1 bioparticle (eBP). Fel d 1 eBP promotes immune tolerance by redirecting allergic Th2 responses toward Th1 and IL‐10–producing regulatory pathways, including Bregs.
Janice A. Layhadi   +16 more
wiley   +1 more source

Omalizumab therapy for treatment of recalcitrant chronic spontaneous urticaria in an Asian population

open access: yes, 2017
Objectives: There are limited data regarding omalizumab in the treatment of recalcitrant chronic spontaneous urticaria (CSU) in Asian populations. This study evaluated the effectiveness and the proper dosage of omalizumab for Asian CSU patients in a real-
Kanokvalai Kulthanan   +4 more
core   +1 more source

Management of Pediatric Chronic Spontaneous Urticaria: A Review of Current Evidence and Guidelines

open access: yesJournal of Asthma and Allergy, 2021
Jasmine Chang,1 Leila Cattelan,2 Moshe Ben-Shoshan,3 Michelle Le,2 Elena Netchiporouk2 1Department of Medicine, McGill University, Montreal, Quebec, Canada; 2Division of Dermatology, McGill University Health Centre, Montreal, Quebec, Canada; 3Division of
Chang J   +4 more
doaj  

Demanding, but definitely worth it! A mixed‐methods study on parental experiences with early‐life oral immunotherapy

open access: yesPediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
Abstract Background Early oral immunotherapy for food allergy (<3 years of age; eOIT) shows promise for inducing sustained unresponsiveness. However, concerns about its feasibility remain. Parental experiences with eOIT have not yet been studied, but understanding these is crucial for improving its clinical implications.
Lieke J. C. Barten   +6 more
wiley   +1 more source

A Comparative, Three-Arm, Randomized Clinical Trial to Evaluate the Effectiveness and Tolerability of Bilastine vs Fexofenadine vs Levocetirizine at the Standard Dose and Bilastine vs Fexofenadine at Higher Than the Standard Dose (Up-Dosing) vs Levocetirizine and Hydroxyzine (in Combination) in Patients with Chronic Spontaneous Urticaria

open access: yesClinical, Cosmetic and Investigational Dermatology, 2022
Bela Shah,1 Dhiraj Dhoot,2 Ankita Choudhary,1 Neha Jangid,1 Deval Mistry,1 Shikha Shah,1 Shruti Kamat,1 Hanmant Barkate3 1Department of Dermatology, Venereology and Leprosy, B.J.Medical College, Civil Hospital, Ahmedabad, India; 2DGM, Department of ...
Shah B   +7 more
doaj  

Codfish Oral Immunotherapy in Children Aged 2–10: Randomized Placebo‐Controlled Study

open access: yesAllergy, Volume 81, Issue 5, Page 1799-1812, May 2026.
Codfish OIT significantly increased desensitization in children with fish allergy (43% vs. 11% placebo, p = 0.003), with 69% achieving 10‐fold threshold increases versus 26% in placebo (p = 0.0003). Sustained unresponsiveness remained limited (23% vs. 9%, p = 0.332). Treatment demonstrated acceptable safety with predominantly mild reactions and reduced
Agnes Sze‐yin Leung   +9 more
wiley   +1 more source

Antihistamines: Recommended Dosage-Divergence between Clinical Practice and Guideline Recommendations

open access: yes, 2019
The updosing of second-generation antihistamines for chronic urticaria is based on inconsistent findings. Herein, we report data on the treatment of children with chronic spontaneous urticaria (CSU) unresponsive to single doses of second-generation H(1 ...
Cuppari, Caterina   +2 more
core   +1 more source

Omalizumab Therapy Results in Defined Behavioural Changes and Improvements in Quality of Life in Solar Urticaria

open access: yesPhotodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 3, May 2026.
ABSTRACT Background Solar urticaria is a rare photodermatosis in which exquisite photosensitivity can require extreme behavioural adaptations, resulting in a substantial impact on quality of life (QoL). Omalizumab therapy has been demonstrated to improve several clinical outcome measures, but the impact on behavioural measures is poorly understood. Our
Donna Parkin   +4 more
wiley   +1 more source

Cardiac safety of second‐generation H 1 ‐antihistamines when updosed in chronic spontaneous urticaria

open access: yesClinical & Experimental Allergy, 2019
Abstract The symptoms of chronic urticaria, be it chronic spontaneous urticaria ( CSU ) or chronic inducible urticaria (CindU), are mediated primarily by the actions of histamine on H 1 receptors located on endothelial cells (the weal)
Mauro Cataldi   +3 more
openaire   +3 more sources

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