Results 61 to 70 of about 578 (168)

Effect on Cell Surface Markers following Allergen-Induced Desensitization of Human Whole-Blood Basophils

, 2010
<i>Background:</i> Allergen-specific immunotherapy (SIT) leads to reduced symptoms upon allergen exposure through as yet unresolved mechanisms.
Jens Holm, Gitte Lund, Per Stahl Skov, Kaare Lund, Henrik Jacobi   +4 more
core   +1 more source

Escape From Synthetic T Cell Activator Tebentafusp by Genomic HLA Loss: A Case Report

HLA, Volume 107, Issue 5, May 2026.
ABSTRACT Tebentafusp, a T‐cell receptor‐bispecific molecule targeting glycoprotein 100‐derived peptide presented by HLA class I molecule and CD3, is standard of care for patients with unresectable or metastatic uveal melanoma who are positive for HLA‐A*02:01. Mechanisms of resistance to tebentafusp are unknown. We report a patient with metastatic uveal
Halime Kalkavan, Andreas Heinold, Siyang Liu, Gaurav M. Borse, Falko M. Heinemann, Thomas Dertnig, Jörg Hense, Marc Ingenwerth, Fung‐Yi Cheung, Georgia Antonopoulou, Ina Pretzell, Katharina Fleischhauer, Nikolaos E. Bechrakis, Martin Schuler   +13 more
wiley   +1 more source

A Pilot Randomised Controlled Dose‐Ranging Trial of Ant Venom Immunotherapy With and Without Delta‐Inulin Adjuvant

Clinical &Experimental Allergy, Volume 56, Issue 4, Page 378-390, April 2026.
Low dose (25mcg) jack jumper ant venom immunotherapy with or without Advax adjuvant, had similar efficacy to the current standard of care. Reduction in basophil activation test reactivity in response to treatment correlated with sting challenge outcome.
Thanh‐Thao Adriana Le, Troy Wanandy, Griffith B. Perkins, Susan Lester, Wun Yee Lau, Malcolm Turner, Richard J. Woodman, Emily M. Mulcahy, Sherin Vareeckal Joseph, Shweta Mhatre, Simon G. A. Brown, Michael D. Wiese, Nikolai Petrovsky, Robert J. Heddle, Pravin Hissaria   +14 more
wiley   +1 more source

Functional and Immunoreactive Levels of IgG4 Correlate with Clinical Responses during the Maintenance Phase of House Dust Mite Immunotherapy

, 2018
Allergen-specific immunotherapy for house dust mite allergy is effective, but there are no validated biomarkers reflecting or predicting the clinical efficacy. We aimed to investigate the relationship between clinical outcomes and functional responses of
Qiujuan Su, Xuxin Lai, Jing Li, Rundong Qin, Mo Xian, Xu Shi, Peter Adler Wurtzen, Mulin Feng, Xiaohui Zeng   +8 more
core   +1 more source

Prolonged IL‐33 Exposure Switches the Secreted Mast Cell Cytokine Profile From Pro‐Inflammatory to Pro‐Tolerant

Allergy, Volume 81, Issue 3, Page 720-733, March 2026.
This study investigates the effect of IL‐33 and Hymenoptera venom on mast cell cytokine profiles under venom immunotherapy (VIT)‐like conditions. Our in vitro model of VIT‐like mast cell stimulation demonstrates a modulatory effect of IL‐33 on the secreted mast cell cytokine profile.
Andrea R. Teufelberger, Carolin Költgen, Magda Babina, Peter Wolf   +3 more
wiley   +1 more source

Rate Of Anaphylaxis Caused By Oral Immunotherapy In Children With Cow's Milk Allergy

, 2014
Rationale The safety represents the major concern for the treatment of IgE mediated food allergy with oral immunotherapy (OIT). The aim of the survey was the detection of the rate of Anaphylaxis during immunotherapy with cow’s milk (CM – OIT).Methods
SALZANO, Giuseppina, Caminiti L., PAJNO, Giovanni Bat., Crisafulli G, ARASI, STEFANIA, Vadalà R, Barberi S   +6 more
core   +1 more source

How to Treat Patients with Chronic Spontaneous Urticaria with Omalizumab: Questions and Answers

, 2020
Omalizumab is an effective treatment for patients with chronic spontaneous urticaria (CSU). In routine clinical practice, physicians often face complex cases of CSU and need to decide whether patients are suitable for omalizumab treatment and how to ...
TÜRK, MURAT, Maurer, Marcus, Kolkhir, Pavel, Carneiro-Leao, Leonor, Bonnekoh, Hanna, Buttgereit, Thomas   +5 more
core   +1 more source

Simulating the impact of an educational and digital approach using patient journey modelling to overcome practical challenges in the management of chronic spontaneous urticaria in Germany

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 3, Page 338-346, March 2026.
Summary Background and Objective Despite the availability of guidelines and effective escalation therapies, chronic spontaneous urticaria (CSU) is often inadequately treated in Germany. Implementation science can help to transfer evidence‐based care into practice.
Ralph von Kiedrowski, Mark Berneburg, Mona Biermann, Hanna Bonnekoh, Michael Fritz, Max Tischler, Martin Metz, Sebastian Volc, Nicola Wagner, Alexander Zink, Petra Nathan   +10 more
wiley   +1 more source

Safety and efficiency of peanut oral immunotherapy in preschool children with slow up-dosing and low maintenance dosing: a randomised controlled trialResearch in context

The Lancet Regional Health. Europe
Summary: Background: Oral immunotherapy (OIT) is an emerging treatment for peanut allergy. A variety of protocols have been investigated, and accumulating evidence suggests that younger children may benefit from greater immune plasticity. The aim of the
Susanna Klevebro, Carina Uhl, Jon Roald Konradsen, Josefin Ullberg, Sandra Ganrud Tedner, Idun Holmdahl, Isabella Badolati, Rui Da Silva Rodrigues, Eva Sverremark-Ekström, Caroline Nilsson, Anna Asarnoj   +10 more
doaj   +1 more source

Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI 2024–2025 Guidelines: From Evidence‐to‐Decision Frameworks to Digitalised Shared Decision‐Making Algorithms

Allergy, Volume 81, Issue 2, Page 427-453, February 2026.
The Allergic Rhinitis and its Impact on Asthma (ARIA) group is working on the 2024–2025 update of its guidelines for the management of allergic rhinitis (ARIA 2024–2025). The ARIA 2024–2025‐EAACI guidelines will follow GRADE methodology and will incorporate evidence from different sources, including systematic reviews and meta‐analyses, mHealth data ...
Jean Bousquet, Bernardo Sousa‐Pinto, Rafael José Vieira, Holger J. Schünemann, Torsten Zuberbier, Antonio Bognanni, Alkis Togias, Boleslaw Samolinski, Arunas Valiulis, Sian Williams, Anna Bedbrook, Wienczyslawa Czarlewski, Maria Jose Torres, Mohamed H. Shamji, Mário Morais‐Almeida, G. Walter Canonica, Leticia de las Vecillas, Mark S. Dykewicz, Cristina Jacomelli, Ludger Klimek, Lucas Leemann, Olga Lourenço, Yuliia Palamarchuk, Nikolaos G. Papadopoulos, Ana Margarida Pereira, Marine Savouré, Sanna K. Toppila‐Salmi, Maria Teresa Ventura, Juan Jose Yepes‐Nuñez, Alvaro A. Cruz, Giorgio Ciprandi, Bilun Gemicioglu, Mattia Giovannini, Brigita Gradauskiene, Tuomas Jartti, Miloš Jeseňák, Piotr Kuna, Violeta Kvedariene, Désirée E. Larenas‐Linnemann, Amir H. A. Latiff, Yousser Mohammad, Ken Ohta, Padukudru A. Mahesh, Isabella Pali‐Schöll, Oliver Pfaar, Frederico S. Regateiro, Nicolas Roche, Mikhail Sofiev, Luís Taborda‐Barata, Charlotte Suppli Ulrik, Marylin Valentin Rostan, Giovanni Viegi, Luo Zhang, Josep M. Antó, Tari Haahtela, Ivan Cherrez‐Ojeda, Juan Carlos Ivancevich, Nikolai Khaltaev, Arzu Yorgancioglu, Baharudin Abdullah, Mona Al‐Ahmad, Maryam Ali Al‐Nesf, Rita Amaral, Julijana Asllani, Karl‐C Bergmann, Jonathan A. Bernstein, Michael S. Blaiss, Fulvio Braido, Paulo Camargos, Pedro Carreiro‐Martins, Thomas Casale, Lorenzo Cecchi, Alessandro G. Fiocchi, Antonio F. M. Giuliano, George Christoff, Ieva Cirule, Jaime Correia‐de‐Sousa, Elisio M. Costa, Stefano Del Giacco, Philippe Devillier, Dejan Dokic, Elham Hossny, Tomohisa Iinuma, Carla Irani, Zhanat Ispayeva, Kaja Julge, Igor Kaidashev, Kazi S. Bennoor, Helga Kraxner, Inger Kull, Marek Kulus, Maciej Kupczyk, Andriy Kurchenko, Stefania La Grutta, Neven Miculinic, Lan Le Thi Tuyet, Michael Makris, Branislava Milenkovic, Sang Min Lee, Stephen Montefort, André Moreira, Joaquim Mullol, Rachel Nadif, Alla Nakonechna, Hugo E. Neffen, Marek Niedoszytko, Dieudonné Nyembue, Robyn O'Hehir, Ismail Ogulur, Yoshitaka Okamoto, Heidi Olze, Oscar Palomares, Petr Panzner, Vincenzo Patella, Ruby Pawankar, Constantinos Pitsios, Todor A. Popov, Francesca Puggioni, Santiago Quirce, Agné Ramonaité, Marysia Recto, Maria Susana Repka‐Ramirez, Graham Roberts, Karla Robles‐Velasco, Menachem Rottem, Marianella Salapatas, Joaquin Sastre, Nicola Scichilone, Juan Carlos Sisul, Dirceu Solé, Manuel E. Soto‐Martinez, Milan Sova, Pongsakorn Tantilipikorn, Ana Todo‐Bom, Vladyslav Tsaryk, Ioanna Tsiligianni, Marilyn Urrutia‐Pereira, Erkka Valovirta, Eric Van Ganse, Tuula Vasankari, Dana Wallace, De Yun Wang, Margitta Worm, Osman M. Yusuf, Mihaela Zidarn, Sara Gil‐Mata, Manuel Marques‐Cruz, Bassam Mahboub, Ignacio J. Ansotegui, Antonino Romano, Maria Cristina Artesani, Bruno Barreto, Sven Becker, Bianca Beghe, Jacques Bouchard, Melisande Bourgoin‐Heck, Luisa Brussino, Roland Buhl, Mario Calvo‐Gil, Victoria Cardona Dahl, José Antonio Castillo Vizuete, Denis Charpin, Niels H. Chavannes, Marta Chełmińska, Lei Cheng, Ekaterine Chkhartishvili, Herberto Jose Chong‐Neto, Deepa Choudhury, Derek Chu, Cemal Cingi, Enrico Compalati, Biljana Cvetkovski, Jane Da Silva, Gennaro D'Amato, Janet Davies, Danilo Di Bona, Maria V. Dimou, Maria Do Ceu Teixeira, Maria Doulaptsi, José Miguel Fuentes Pérez, Radoslaw Gawlik, Ozlem Goksel, Maximiliano R. Gómez, Sandra N. Gonzalez Diaz, Maia Gotua, Christos Grigoreas, Ineta Grisle, Maria Antonieta Guzman, Rachel House Tan, Michael Hyland, Despo Ierodiakonou, Aspasia Karavelia, Marta Kisiel, Mitja Kosnik, Vicky Kritikos, Carlo Lombardi, Matteo Martini, Cem Meço, Eris Mesonjesi, Florin Mihaltan, Marcin Moniuszko, Robert Naclerio, Sophia Neisinger, Michal Ordak, Giovanni Paoletti, Edgar Arturo Perdomo‐Flores, Nhan Pham‐Thi, Emmanuel Prokopakis, Daniela Rivero Yeverino, Giovanni Rolla, Jan Romantowski, Philip W. Rouadi, Maia Rukhadze, Daiju Sakurai, Laila Salameh, Faradiba Serpa Sarquis, Tanja Soklic Kosak, Michael Soyka, Olga Sozinova, Krzysztof Specjalski, Vesna Tomic‐Spiric, Martina Vachova, Marianne van Hage, Ilgim Vardaloglu Koyuncu, Pakit Vichyanond, Martin Wagenmann, Fanny Wai San Ko, Pascal Werminghaus, Vicky Paraskevi Xepapadaki, Yi‐Kui Xiang, João A. Fonseca   +230 more
wiley   +1 more source