Results 71 to 80 of about 1,790,928 (250)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Upper and lower solution method for boundary value problems at resonance
Electronic Journal of Qualitative Theory of Differential Equations, 2016 We consider two simple boundary value problems at resonance for an ordinary differential equation. Employing a shift argument, a regular fixed point operator is constructed. We employ the monotone method coupled with a method of upper and lower solutions
Samerah Al Mosa, Paul Eloe
doaj +1 more source
Integral-Partial Differential Equations of Isaacs' Type Related to Stochastic Differential Games with Jumps [PDF]
, 2010 In this paper we study zero-sum two-player stochastic differential games with jumps with the help of theory of Backward Stochastic Differential Equations (BSDEs).
Buckdahn, Rainer, Hu, Ying, Li, Juan
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
International Journal of Differential Equations, 2011 We consider a kind of Sturm-Liouville boundary value problems. Using variational techniques combined with the methods of upper-lower solutions, the existence of at least one positive solution is established.
Li Zhang, Xiankai Huang, Weigao Ge
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
On lower and upper solutions without ordering on time scales
Advances in Difference Equations, 2006 In order to enlarge the set of boundary value problems on time scales, for which we can use the lower and upper solutions technique to get existence of solutions, we extend this method to the case when the pair lacks ordering.
Stehlík Petr
doaj
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Method of upper and lower solutions for fractional differential equations
Electronic Journal of Differential Equations, 2012 In this paper, we show the existence and uniqueness of solutions for the boundary-value problems of fractional differential equations, using the upper and lower solutions method and monotone iterative algorithm.
Legang Lin, Xiping Liu, Haiqin Fang
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