Results 51 to 60 of about 5,042,325 (288)

3-4 day Kelvin waves observed in the MLT region at 7.4o S, Brazil [PDF]

open access: yesGeofísica Internacional, 2008
Meteor wind measurements obtained from São João do Cariri-PB (7.4° S, 36.5° W), Brazil, during 2005, have been used to examine the ultra-fast Kelvin wave characteristics in the mesopause and lower thermosphere region.
P. P. Batista   +6 more
doaj  

The GFDL Global Atmospheric Chemistry‐Climate Model AM4.1: Model Description and Simulation Characteristics

open access: yesJournal of Advances in Modeling Earth Systems, 2020
We describe the baseline model configuration and simulation characteristics of the Geophysical Fluid Dynamics Laboratory (GFDL)'s Atmosphere Model version 4.1 (AM4.1), which builds on developments at GFDL over 2013–2018 for coupled carbon‐chemistry ...
Larry W. Horowitz   +15 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Modeling of the effect of internal gravity waves on upper atmospheric conditions during sudden stratospheric warming

open access: yesSolar-Terrestrial Physics, 2016
We present results of modeling of the effect of internal gravity waves (IGW), excited in the region of development of a sudden stratospheric warming (SSW), on upper atmospheric conditions.
Vasilyev P.A.   +2 more
doaj   +1 more source

Stratospheric warming influence on the mesosphere/lower thermosphere as seen by the extended CMAM [PDF]

open access: yesAnnales Geophysicae, 2014
The response of the upper mesosphere/lower thermosphere region to major sudden stratospheric warming (SSW) is examined employing temperature, winds, NOX and CO constituents from the extended Canadian Middle Atmosphere Model (CMAM) with continuous ...
M. G. Shepherd   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Climate, Variability, and Climate Sensitivity of “Middle Atmosphere” Chemistry Configurations of the Community Earth System Model Version 2, Whole Atmosphere Community Climate Model Version 6 (CESM2(WACCM6))

open access: yesJournal of Advances in Modeling Earth Systems, 2023
Simulating whole atmosphere dynamics, chemistry, and physics is computationally expensive. It can require high vertical resolution throughout the middle and upper atmosphere, as well as a comprehensive chemistry and aerosol scheme coupled to radiation ...
N. A. Davis   +13 more
doaj   +1 more source

A Review of the Dynamics and Oscillations of the Atmosphere [PDF]

open access: yes, 2012
The atmosphere is a complex, dynamic system and the weather depends on its state. There are many different phenomena that affect the state of the atmosphere - some only involve the atmosphere, others involve the interaction between the atmosphere and the
Ross, Joseph
core  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

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