Results 41 to 50 of about 432,921 (266)

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar   +7 more
wiley   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan   +18 more
wiley   +1 more source

Minimum Symbol Error Probability MIMO Design under the Per-Antenna Power Constraint

open access: yesJournal of Electrical and Computer Engineering, 2012
Approximate minimum symbol error probability transceiver design of single user MIMO systems under the practical per-antenna power constraint is considered.
Enoch Lu, I.-Tai Lu
doaj   +1 more source

A Simplified Method for Predicting Pattern Match Ratio

open access: yesFrontiers in Psychology, 2021
Cognitive diagnostic test design (CDTD) has a direct impact on the pattern match ratio (PMR) of the classification of examinees. It is more helpful to know the quality of a test during the stage of the test design than after the examination is taken. The
Xiaojuan Tang   +3 more
doaj   +1 more source

Upper Tail Bounds for Cycles

open access: yesSIAM Journal on Discrete Mathematics, 2020
This paper examines bounds on upper tails for cycle counts in $G_{n,p}$. For a fixed graph $H$ define $ξ_H= ξ_H^{n,p}$ to be the number of copies of $H$ in $G_{n,p}$. It is a much studied and surprisingly difficult problem to understand the upper tail of the distribution of $ξ_H$, for example, to estimate \begin{equation*} \mathbb{P}(ξ_H > 2 \mathbb{
openaire   +3 more sources

Mapping Childhood Cancer Care Services in Oceania: Methodological Lessons From the SIOP Global Mapping Programme

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT The International Paediatric Oncology Society Global Mapping Programme aims to collect data on global paediatric oncology services by continent, with Africa and Latin America completed. This study reports on the methodology and lessons learned for Oceania, a unique continent with resource disparity across countries, multiple small island ...
Trisha Soosay Raj   +16 more
wiley   +1 more source

On the Distance to a Root of Polynomials

open access: yesAbstract and Applied Analysis, 2011
In 2002, Dierk Schleicher gave an explicit estimate of an upper bound for the number of iterations of Newton's method it takes to find all roots of polynomials with prescribed precision. In this paper, we provide a method to improve the upper bound given
Somjate Chaiya
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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