Results 51 to 60 of about 2,566,965 (290)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
On the Distance to a Root of Polynomials
Abstract and Applied Analysis, 2011 In 2002, Dierk Schleicher gave an explicit estimate of an upper bound for the number of iterations of Newton's method it takes to find all roots of polynomials with prescribed precision. In this paper, we provide a method to improve the upper bound given
Somjate Chaiya
doaj +1 more source
Performance Analysis of Polar Codes Over Fox’s H-Fading Channels With RHI and IQI Impairments
IEEE Access, 2023 This study examined the error probability performance of polar codes across Fox’s $H$ -fading (FHF) channels while taking into account in-phase and quadrature-phase imbalance (IQI), as well as residual hardware impairments (RHI).
Souad Labghough +4 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Linear programming bounds for doubly-even self-dual codes [PDF]
, 1997 Using a variant of linear programming method we derive a new upper bound on the minimum distance d of doubly-even self-dual codes of length n. Asymptotically, for n growing, it gives d/n
Krasikov, I +4 more
core +2 more sources
EHAUPM: Efficient High Average-Utility Pattern Mining With Tighter Upper Bounds
IEEE Access, 2017 High-utility itemset mining (HUIM) has become a popular data mining task, as it can reveal patterns that have a high-utility, contrarily to frequent pattern mining, which focuses on discovering frequent patterns.
Jerry Chun-Wei Lin +3 more
doaj +1 more source
Machines, 2023 An upper bound analysis of free-chip machining has been carried out, where the tool cutting and friction forces were determined from the deformation energy dissipated during the chip separation process.
Hillol Joardar +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Sculpture education program / Upper Iowa Univesity
, 1998 [Title], Upper Iowa University Digital Archives, [Reference URL].
Upper Iowa University
core +1 more source