Results 61 to 70 of about 2,566,965 (290)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Classical Lower Bounds from Quantum Upper Bounds [PDF]
2018 IEEE 59th Annual Symposium on Foundations of Computer Science (FOCS), 2018 46 pages; to appear at FOCS ...
Shalev Ben-David +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
A fully implicit, lower bound, multi-axial solution strategy for direct ratchet boundary evaluation : implementation and comparison [PDF]
, 2014 Ensuring sufficient safety against ratcheting is a fundamental requirement in pressure vessel design. However, determining the ratchet boundary using a full elastic plastic finite element analysis can be problematic and a number of direct methods have ...
Jappy, Alan +2 more
core +4 more sources
Remarks on the Upper Bound Theorem
Journal of Combinatorial Theory, Series A, 2003 An extension of the known upper bound theorem for convex polytopes in \(\mathbb{R}^d\) is the so-called strong upper bound theorem due to Gil Kalai, holding for the boundary complexes of simplicial polytopes and their full-dimensional subcomplexes. The author gives an extension of this theorem for even-dimensional simplicial manifolds.
openaire +2 more sources
Examining the Limits of Predictability of Human Mobility
Entropy, 2019 We challenge the upper bound of human-mobility predictability that is widely used to corroborate the accuracy of mobility prediction models. We observe that extensions of recurrent-neural network architectures achieve significantly higher prediction ...
Vaibhav Kulkarni +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Upper Iowa University campus, 1908
, 1908 Two photographic views of campus. Top view is taken looking uphill from the west. Left to right: (some buildings behind trees) are Science Hall [no longer exists; now location of Colgrove-Walker]; Main Building [now Alexander-Dickman]; Ladies Hall [no ...
Upper Iowa University
core +1 more source
Upper bounds of differential branch number of $$n$$ n -bit permutations
CybersecurityThe differential branch number is a key parameter used to measure the diffusion ability of a permutation. It is of great significance to study the upper bound of the differential branch number of permutations. This paper analyses the existence problem of
Ying Gao, Lin Qi
doaj +1 more source
Yantu gongcheng xuebao, 2019 According to the determination of the rock pressures and collapse mechanisms of tunnels, the finite element upper-bound method with rigid translatory moving elements (UBFEM-RTME) is used to obtain the upper bound solution charts of the supporting force ...
SHI Yu-feng 1,2, XU Chang-jie 1, YANG Feng 3,4, LUO Jing-jing 3, YANG Jun-sheng 3,4
doaj +1 more source