Results 61 to 70 of about 432,921 (266)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Upper bounds of differential branch number of $$n$$ n -bit permutations
The differential branch number is a key parameter used to measure the diffusion ability of a permutation. It is of great significance to study the upper bound of the differential branch number of permutations. This paper analyses the existence problem of
Ying Gao, Lin Qi
doaj +1 more source
According to the determination of the rock pressures and collapse mechanisms of tunnels, the finite element upper-bound method with rigid translatory moving elements (UBFEM-RTME) is used to obtain the upper bound solution charts of the supporting force ...
SHI Yu-feng 1,2, XU Chang-jie 1, YANG Feng 3,4, LUO Jing-jing 3, YANG Jun-sheng 3,4
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Analytical Investigation of Rupture Phenomena in Sheet Hydro-forming Process by Hemispherical Punch [PDF]
Rupture and wrinkling are two prevalent phenomena that happen in hydro-forming process. Many efforts have been made to achieve the upper and lower bounds for the pressure related to rupture and wrinkling of sheet, respectively.
Alireza Naddaf Oskouei +2 more
doaj
A geometrical upper bound on the inflaton range
We argue that in type IIB LVS string models, after including the leading order moduli stabilisation effects, the moduli space for the remaining flat directions is compact due the Calabi-Yau Kähler cone conditions. In cosmological applications, this gives
Michele Cicoli +3 more
doaj +1 more source
Upper Bounds for Turán Numbers
The Turán number \(T(n,k,r)\) is the minimum size of a system of \(r\)-subsets of an \(n\)-set such that every \(k\)-subset contains at least one of the members of the system. The paper gives asymptotic upper bounds for these numbers. Constructive upper bounds in case that \(k=2r+1\) have been given by \textit{D. de Caen} et al. [Congr. Numerantium 65,
openaire +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Upper bound of holographic entanglement entropy combinations
In this work, we develop a systematic formalism to evaluate the upper bound of a large family of holographic entanglement entropy combinations when fixing n subsystems and fine-tuning one other subsystem.
Xin-Xiang Ju, Ya-Wen Sun, Yang Zhao
doaj +1 more source

