Results 61 to 70 of about 2,232,659 (281)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Examining the Limits of Predictability of Human Mobility

open access: yesEntropy, 2019
We challenge the upper bound of human-mobility predictability that is widely used to corroborate the accuracy of mobility prediction models. We observe that extensions of recurrent-neural network architectures achieve significantly higher prediction ...
Vaibhav Kulkarni   +3 more
doaj   +1 more source

Performance Analysis of Polar Codes Over Fox’s H-Fading Channels With RHI and IQI Impairments

open access: yesIEEE Access, 2023
This study examined the error probability performance of polar codes across Fox’s $H$ -fading (FHF) channels while taking into account in-phase and quadrature-phase imbalance (IQI), as well as residual hardware impairments (RHI).
Souad Labghough   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Rock pressures of tunnels based on finite element upper bound analysis method with rigid moving elements

open access: yesYantu gongcheng xuebao, 2019
According to the determination of the rock pressures and collapse mechanisms of tunnels, the finite element upper-bound method with rigid translatory moving elements (UBFEM-RTME) is used to obtain the upper bound solution charts of the supporting force ...
SHI Yu-feng 1,2, XU Chang-jie 1, YANG Feng 3,4, LUO Jing-jing 3, YANG Jun-sheng 3,4
doaj   +1 more source

An upper bound on Reidemeister moves [PDF]

open access: yes, 2011
We provide an explicit upper bound on the number of Reidemeister moves required to pass between two diagrams of the same link. This leads to a conceptually simple solution to the equivalence problem for links.Comment: 40 pages, 14 figures; v2: very minor
Coward, Alexander, Lackenby, Marc
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Analytical Investigation of Rupture Phenomena in Sheet Hydro-forming Process by Hemispherical Punch [PDF]

open access: yesInternational Journal of Advanced Design and Manufacturing Technology, 2014
Rupture and wrinkling are two prevalent phenomena that happen in hydro-forming process. Many efforts have been made to achieve the upper and lower bounds for the pressure related to rupture and wrinkling of sheet, respectively.
Alireza Naddaf Oskouei   +2 more
doaj  

A geometrical upper bound on the inflaton range

open access: yesJournal of High Energy Physics, 2018
We argue that in type IIB LVS string models, after including the leading order moduli stabilisation effects, the moduli space for the remaining flat directions is compact due the Calabi-Yau Kähler cone conditions. In cosmological applications, this gives
Michele Cicoli   +3 more
doaj   +1 more source

An analysis of the SPARSEVA estimate for the finite sample data case

open access: yes, 2018
In this paper, we develop an upper bound for the SPARSEVA (SPARSe Estimation based on a VAlidation criterion) estimation error in a general scheme, i.e., when the cost function is strongly convex and the regularized norm is decomposable for a pair of ...
Ha, Huong   +3 more
core   +1 more source

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