Results 41 to 50 of about 861,443 (311)
Clinical MedicineObjective: Determining the accuracy of a method calculating the Gold Standards Framework Surprise Question (GSFSQ) equivalent end-of-life prognosis amongst hospital inpatients.
Baldev Singh +8 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
EBioMedicineSummary: Background: Current methods for identifying end-of-life cannot be applied systematically to large populations. We have developed, tested, validated a mortality probability algorithm with that level of scalability.
Baldev M. Singh +10 more
doaj +1 more source
Epidemiology of dysmenorrhea among workers in Upper Egypt; A cross sectional study
Middle East Fertility Society Journal, 2018 Objective: To investigate the epidemiology of dysmenorrhea amongst women in two textile factories in Beni-Suef, Egypt compared to non-working controls. Study design: A cross sectional study. Setting: Beni-Suef, Egypt. Materials and methods: The study was
Ahmed E. Arafa +4 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Education for peace in the cross as a pillar upper level [PDF]
Ra Ximhai, 2012 Peace education is very important in our lives, prepare us to be peacemakers, in a problematic world, with high manifestations of different ways of violence.
Concepción Noemí Martínez Real
doaj
Global T operator bounds on electromagnetic scattering: Upper bounds on far-field cross sections
Physical Review Research, 2020 We present a method based on the scattering T operator, and conservation of net real and reactive power, to provide physical bounds on any electromagnetic design objective that can be framed as a net radiative emission, scattering or absorption process ...
Sean Molesky +3 more
doaj +1 more source
Upper bounds for ropelength as a function of crossing number
Topology and its Applications, 2004 The paper provides bounds for the ropelength of a link in terms of the crossing numbers of its split components. As in earlier papers, the bounds grow with the square of the crossing number; however, the constant involved is a substantial improvement on previous results. The proof depends essentially on writing links in terms of their arc-presentations,
Cantarella, Jason +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source