Results 51 to 60 of about 861,443 (311)

Single molecule studies of dynamic platelet interactions with endothelial cells

Frontiers in Bioengineering and Biotechnology
A biotechnological platform consisting of two-color 3D super-resolution readout and a microfluidic system was developed to investigate platelet interaction with a layer of perfused endothelial cells under flow conditions.
Fabian Hauser, Fabian Hauser, Christoph Naderer, Eleni Priglinger, Eleni Priglinger, Anja Peterbauer, Michael B. Fischer, Michael B. Fischer, Heinz Redl, Heinz Redl, Jaroslaw Jacak, Jaroslaw Jacak, Jaroslaw Jacak   +12 more
doaj   +1 more source

Upper gastrointestinal symptoms in autoimmune gastritis

Medicine, 2017
Autoimmune gastritis is often suspected for its hematologic findings, and rarely the diagnosis is made for the presence of gastrointestinal symptoms. Aims of this cross-sectional study were to assess in a large cohort of patients affected by autoimmune gastritis the occurrence and the pattern of gastrointestinal symptoms and to evaluate whether ...
CARABOTTI, MARILIA, LAHNER, EDITH, ESPOSITO, GIANLUCA, SACCHI, MARIA CARLOTTA, SEVERI, Carola, ANNIBALE, Bruno   +5 more
openaire   +3 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Development and Validation of an Instrument for Upper Cross Syndrome: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: A sedentary lifestyle causes muscular imbalances and may lead to upper cross syndrome. This syndrome occurs due to the muscular imbalance of tonic and phasic muscles.
Sharmila Chaudhuri, Meena Gupta, Vandana Phadke, Jasmine Kaur Chawla   +3 more
doaj   +1 more source

Screening for Upper Cross Syndrome in Asymptomatic Individuals

Indian Journal of Forensic Medicine & Toxicology, 2021
Background: Upper cross syndrome has become prevalent in today’s population. This syndrome refers totightness of muscles such as pectoralis major, upper trapezius and levator scapulae and weakness of deepneck flexors, scalene, rombhoids, serratus anterior, middle and lower trapezius.
openaire   +2 more sources

Upper Bound on the Dark Matter Total Annihilation Cross Section [PDF]

Physical Review Letters, 2007
We consider dark matter annihilation into Standard Model particles and show that the least detectable final states, namely neutrinos, define an upper bound on the total cross section. Calculating the cosmic diffuse neutrino signal, and comparing it to the measured terrestrial atmospheric neutrino background, we derive a strong and general bound.
Beacom, John F., Bell, Nicole F., Mack, Gregory D.   +2 more
openaire   +4 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Bending reinforcement of timber beams with steel cross sections on the upper face

Materiales de Construccion, 2010
A procedure for the reinforcement of timber floor joists in ancient buildings using steel U shape cross sections screwed to timber from the upper side is described.
Carlos González-Bravo, Francisco Arriaga-Martitegui, Luis Maldonado-Ramos, Rafael Díez-Barra   +3 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source