Results 51 to 60 of about 846,466 (261)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The accuracy of an electronic-Surprise-Question defining end-of-life cohorts in a whole adult population by algorithmic digital risk stratification: the Proactive Risk-Based and Data-Driven Assessment of Patients at the End of Life (PRADA)Research in context

EBioMedicine
Summary: Background: Current methods for identifying end-of-life cannot be applied systematically to large populations. We have developed, tested, validated a mortality probability algorithm with that level of scalability.
Baldev M. Singh, Nisha Kumari-Dewat, Vijay Klaire, Jonathan Lampitt, Amy Palmer, Adam Ryder, Kamran Ahmed, Mona Sidhu, Hannah Jennens, Ananth Viswanath, Emma Parry   +10 more
doaj   +1 more source

Epidemiology of dysmenorrhea among workers in Upper Egypt; A cross sectional study

Middle East Fertility Society Journal, 2018
Objective: To investigate the epidemiology of dysmenorrhea amongst women in two textile factories in Beni-Suef, Egypt compared to non-working controls. Study design: A cross sectional study. Setting: Beni-Suef, Egypt. Materials and methods: The study was
Ahmed E. Arafa, Yasser Khamis, Hanan E. Hassan, Nahed M. Saber, Ahmed M. Abbas   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Education for peace in the cross as a pillar upper level [PDF]

Ra Ximhai, 2012
Peace education is very important in our lives, prepare us to be peacemakers, in a problematic world, with high manifestations of different ways of violence.
Concepción Noemí Martínez Real
doaj  

Global T operator bounds on electromagnetic scattering: Upper bounds on far-field cross sections

Physical Review Research, 2020
We present a method based on the scattering T operator, and conservation of net real and reactive power, to provide physical bounds on any electromagnetic design objective that can be framed as a net radiative emission, scattering or absorption process ...
Sean Molesky, Pengning Chao, Weiliang Jin, Alejandro W. Rodriguez   +3 more
doaj   +1 more source

Upper bounds for ropelength as a function of crossing number

Topology and its Applications, 2004
The paper provides bounds for the ropelength of a link in terms of the crossing numbers of its split components. As in earlier papers, the bounds grow with the square of the crossing number; however, the constant involved is a substantial improvement on previous results. The proof depends essentially on writing links in terms of their arc-presentations,
Cantarella, Jason, Faber, X.W.C, Mullikin, Chad A   +2 more
openaire   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Single molecule studies of dynamic platelet interactions with endothelial cells

Frontiers in Bioengineering and Biotechnology
A biotechnological platform consisting of two-color 3D super-resolution readout and a microfluidic system was developed to investigate platelet interaction with a layer of perfused endothelial cells under flow conditions.
Fabian Hauser, Fabian Hauser, Christoph Naderer, Eleni Priglinger, Eleni Priglinger, Anja Peterbauer, Michael B. Fischer, Michael B. Fischer, Heinz Redl, Heinz Redl, Jaroslaw Jacak, Jaroslaw Jacak, Jaroslaw Jacak   +12 more
doaj   +1 more source