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Association between household coal use duration and upper gastrointestinal cancer and precancerous lesions: a cross-sectional study [PDF]

open access: yesFrontiers in Public Health
BackgroundTo explore the association between household coal use duration and upper gastrointestinal cancer and precancerous lesions.MethodsThis study is a cross-sectional study.
Kai Xu   +10 more
doaj   +2 more sources

Adrenal insufficiency after curative-intent gastric cancer treatment: a case report

open access: yesJournal of Medical Case Reports, 2023
Background Adrenal insufficiency is a life-threatening condition, and advanced gastric cancer is associated with very poor prognosis. Adrenalectomy and/or metastatic invasion of the adrenal glands can cause primary adrenal insufficiency, which in turn ...
Johan Hardvik Åkerström   +1 more
doaj   +1 more source

Adjuvant SOX chemotherapy versus concurrent chemoradiotherapy after D2 radical resection of locally advanced esophagogastric junction (EGJ) adenocarcinoma: study protocol for a randomized phase III trial (ARTEG)

open access: yesTrials, 2021
Background Survival benefit of adjuvant radiotherapy for locally advanced gastric cancer following gastrectomy plus D2 lymphadenectomy has always been controversial.
Jinwen Shen   +11 more
doaj   +1 more source

A literature review on the potential clinical implications of streptococci in gastric cancer

open access: yesFrontiers in Microbiology, 2022
Streptococcus is widely found in nature and the human body, and most species are not pathogenic. In recent years, studies have found that Streptococcus is associated with gastric cancer.
Mengli Zi   +18 more
doaj   +1 more source

CD10 and Das1: a biomarker study using immunohistochemistry to subtype gastric intestinal metaplasia

open access: yesBMC Gastroenterology, 2022
Background Intestinal metaplasia (IM) is considered a key pivot point in the Correa model of gastric cancer (GC). It is histologically subtyped into the complete and incomplete subtypes, the latter being associated with a greater risk of progression ...
Athanasios Koulis   +6 more
doaj   +1 more source

Trametes robiniophila Murr Sensitizes Gastric Cancer Cells to 5-Fluorouracil by Modulating Tumor Microenvironment

open access: yesFrontiers in Pharmacology, 2022
Trametes robiniophila Murr (TRM) is a traditional Chinese medicine which has been used in clinics for enhancing immunity and improving the efficacy of chemotherapy. However, the mechanisms of action of TRM are unknown.
Jing-Li Xu   +22 more
doaj   +1 more source

Targeting CLDN18.2 in cancers of the gastrointestinal tract: New drugs and new indications

open access: yesFrontiers in Oncology, 2023
Cancers of the gastrointestinal (GI) tract greatly contribute to the global cancer burden and cancer-related death. Claudin-18.2(CLDN18.2), a transmembrane protein, is a major component of tight junctions and plays an important role in the maintenance of
Jinxia Chen   +16 more
doaj   +1 more source

Protein degradation technology: a strategic paradigm shift in drug discovery

open access: yesJournal of Hematology & Oncology, 2021
Targeting pathogenic proteins with small-molecule inhibitors (SMIs) has become a widely used strategy for treating malignant tumors. However, most intracellular proteins have been proven to be undruggable due to a lack of active sites, leading to a ...
Haobin Li   +5 more
doaj   +1 more source

The role of macrophages in gastric cancer

open access: yesFrontiers in Immunology, 2023
As one of the deadliest cancers of the gastrointestinal tract, there has been limited improvement in long-term survival rates for gastric cancer (GC) in recent decades.
Jiaqing Zhang   +32 more
doaj   +1 more source

Clinical and genomic characterization of pancreatic ductal adenocarcinoma patients with lung oligometastasis

open access: yesESMO Gastrointestinal Oncology, 2023
Background: Lung-only relapse following resection of pancreatic ductal adenocarcinoma (PDAC) is rare. While oligometastatic lung disease (OMLD) is detected after PDAC resection, its clinical and molecular features remain unclear.
N.S. Tissera   +14 more
doaj   +1 more source

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