Results 41 to 50 of about 1,974,559 (294)

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Hawkins Award 2025: clinical implications of radiological findings associated with radial head replacement. A long-term follow-up study

JSES International
Background: Radial head replacement (RHR) is indicated in comminuted fractures and those associated with elbow instability. Despite satisfactory clinical outcomes, some patients present with concerning radiographic findings.
Blanca Diez Sánchez, MD, PhD, Luis Palacios-Díaz, MD, Pablo Sánchez-Urgellés, MD, Raúl Barco, MD, PhD, FEBOT, Samuel A. Antuña, MD, PhD, FEBOT   +4 more
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Predicting Pathological Fractures at Metastatic Humeral Lesions

JBJS Open Access, 2023
Background:. The humerus is the second most common site of metastatic disease involving long bones, yet it is still unclear which patients are at high risk for a fracture and may require prophylactic surgical fixation.
Jimmy Tat, MD, MSc, David Bodansky, BMedSc(hons), MBChB, FRCS, Ujash Sheth, MD, MSc, FRCSC, Yee Ung, MD, FRCPC, Cari Whyne, PhD, Diane Nam, MSc, MD, FRCSC   +5 more
doaj   +1 more source

Maintained physical activity and physiotherapy in the management of distal upper limb pain – a protocol for a randomised controlled trial (the Arm Pain Trial) [PDF]

, 2014
Background Upper limb pain is a common cause of disability, demand for health care and lost work time. It is more likely to become persistent if it is accompanied by poor mental health, tendency to somatise, and negative beliefs concerning health and
Jones, Gareth T, Coggon, D., Macfarlane, G.J., Burton, K., Palmer, Keith T., McNamee, P., Jones, Gareth T., Coggon, David, Walker-Bone, Karen, Macfarlane, Gary J, Mertens, K., McCabe, C., McConnachie, A., Macfarlane, Gary J., Palmer, Keith T, Walker-Bone, K., McCabe, Candy, Heine, P.J., Burton, Kim, Mertens, Kathrin, Heine, Peter J, McNamee, Paul, Burton, A. Kim, McConnachie, Alex, Palmer, K. T., Palmer, K.T., Heine, Peter J., Coggon, D. (David), Dr., Jones, G.T., Karen Walker-Bone, Paul McNamee, Kathrin Mertens, Peter J Heine, Gary J Macfarlane, Alex McConnachie, Kim Burton, Gareth T Jones, Keith T Palmer, Candy McCabe, David Coggon   +39 more
core   +2 more sources

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

An intra‐bone axial load transducer: development and validation in an in‐vitro radius model

Journal of Experimental Orthopaedics, 2015
Background Accurate measurement of forces through the proximal radius can assess the effects of some surgical procedures on radioulnar load sharing, but is difficult to achieve given the redundant loading nature of the musculoskeletal system.
Nikolas K. Knowles, Michael Gladwell, Louis M. Ferreira   +2 more
doaj   +1 more source

A narrative review and content analysis of functional and quality of life measures used to evaluate the outcome after TSA: an ICF linking application

BMC Musculoskeletal Disorders, 2020
Background Total shoulder arthroplasty (TSA) is considered as the standard reconstructive surgery for patients suffering from severe shoulder pain and dysfunction caused by arthrosis. Multiple patient-reported outcome measures (PROMs) have been developed
Ze Lu, Joy C. MacDermid, Peter Rosenbaum
doaj   +1 more source