Results 51 to 60 of about 1,974,559 (294)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Technical Guide and Tips to Anterior Arthroscopic Latissimus Dorsi Transfer for Irreparable Subscapularis Tears

Arthroscopy Techniques, 2020
In young patients, irreparable subscapularis tears can be managed by latissimus dorsi (LD) transfer on the lesser tuberosity. We provide a technical guide for isolated LD anterior transfer.
Thibault Lafosse, M.D., Thibaut Fortané, M.D., Andrew McBride, M.D., Yves Salentiny, M.D., Koray Sahin, M.D., Laurent Lafosse, M.D.   +5 more
doaj   +1 more source

A new 147-56 hPa water vapor product from the UARS Microwave Limb Sounder [PDF]

, 2004
Measurements of H2O in the tropopause region have been obtained by production of a new data set from the Microwave Limb Sounder (MLS) on the Upper Atmosphere Research Satellite (UARS).
Waters, J. W., D. L. Wu, Wu, D. L., J. W. Waters, W. G. Read, Read, W. G., Pumphrey, H. C., H. C. Pumphrey   +7 more
core   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Validation of Aura Microwave Limb Sounder O-3 and CO observations in the upper troposphere and lower stratosphere [PDF]

, 2008
Global satellite observations of ozone and carbon monoxide from the Microwave Limb Sounder (MLS) on the EOS Aura spacecraft are discussed with emphasis on those observations in the 215-100 hPa region (the upper troposphere and lower stratosphere).
Perun, V. S., Gao, R. S., Waters, J. W., Wagner, P. A., Fuller, R. A., Loewenstein, M., Diskin, G. S., Cuddy, D. T., Cammas, J. -P., Read, W. G., Drouin, B. J., Jarnot, R. F., Christensen, L. E., Lopez, J.D., Webster, C. R., Thurstans, R. P., Jost, H. J., Cammas, Jean-Pierre, Lambert, A., Li, Q. B., Pumphrey, Hugh, Schwartz, M. J., Livesey, N. J., Filipiak, M. J., Knosp, B. W., Gao, R. -S., Jiang, J. H., Daffer, W. H., Jost, H. -J., Stek, P. C., Sachse, G. W., Avery, M., Jiang, Y. B., Browell, E. V., Cofield, R. E., Snyder, W. V., Froidevaux, L., Santee, M. L., Osterman, G. B., Nedelec, P., Browell, E.-V., Webster, R. C., Filipiak, Mark, Cofield, R.E., Lopez, J. D., Pumphrey, H. C.   +45 more
core   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Complex Hand Reconstruction using a Novel Two‐stage Temporary Ectopic Implantation of the Contralateral Upper Limb

Orthopaedic Surgery
Ectopic transplantation of the hand remains a rare, innovative yet valuable operation in select cases of trauma and amputation. We aim to describe a novel technique of complex hand reconstruction using a two‐stage ectopic implantation of the ...
Haiquan Long, Di Wu, Zuojie Yan, Sailing Jia, Jin Ren Chen, Rebecca Qian Ru Lim   +5 more
doaj   +1 more source

Arthroscopic matched osteoplasty of the radial head for painful radiocapitellar osteoarthritis: surgical technique and case series [PDF]

Clinics in Shoulder and Elbow
Background Radiocapitellar arthritis can cause pain, loss of motion, and impaired elbow function. Current surgical treatment options are limited. We have developed an original and simple surgical technique to address this, called arthroscopic matched ...
Dani Rotman, Adam C Watts
doaj   +1 more source