Results 51 to 60 of about 304,357 (316)

Skill assessment in upper limb myoelectric prosthesis users: Validation of a clinically feasible method for characterising upper limb temporal and amplitude variability during the performance of functional tasks [PDF]

, 2017
Upper limb myoelectric prostheses remain challenging to use and are often abandoned. A proficient user must be able to plan/execute arm movements while activating the residual muscle(s), accounting for delays and unpredictability in prosthesis response ...
Thies, Sibylle B., Stine, R, Major, Mathew J., Laurence PJ Kenney, Kyberd, Peter, Kenney, P.J., Kenney, LPJ, Major, M., Peter Kyberd, Kyberd, P, Galpin, AJ, Kyberd, P., Matthew J Major, Sobhu, M., Major, Matthew J., Galpin, Adam, Stine, Rebecca, Kenney, Laurence P. J., Sibylle B Thies, Thies, Sybille B., Sobuh, Mohammad, Major, MJ, Thies, SBA, Thies, S., Sobuh, M, Galpin, A., Stine, R., Mohammad Sobuh, Rebecca Stine, Adam Galpin   +29 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

An intra‐bone axial load transducer: development and validation in an in‐vitro radius model

Journal of Experimental Orthopaedics, 2015
Background Accurate measurement of forces through the proximal radius can assess the effects of some surgical procedures on radioulnar load sharing, but is difficult to achieve given the redundant loading nature of the musculoskeletal system.
Nikolas K. Knowles, Michael Gladwell, Louis M. Ferreira   +2 more
doaj   +1 more source

Technical Guide and Tips to Anterior Arthroscopic Latissimus Dorsi Transfer for Irreparable Subscapularis Tears

Arthroscopy Techniques, 2020
In young patients, irreparable subscapularis tears can be managed by latissimus dorsi (LD) transfer on the lesser tuberosity. We provide a technical guide for isolated LD anterior transfer.
Thibault Lafosse, M.D., Thibaut Fortané, M.D., Andrew McBride, M.D., Yves Salentiny, M.D., Koray Sahin, M.D., Laurent Lafosse, M.D.   +5 more
doaj   +1 more source

Work-related upper limb disorder:- An investigative study [PDF]

, 2005
The primary aim of occupational health staff within a manufacturing company is to ensure the health and well being of the employees are safeguarded. The aim may be difficult to achieve as it goes directly against the ethos of business, i.e. making money.
Jenkinson, Janice
core  

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Cirrus and water vapor in the tropical tropopause layer observed by Upper Atmosphere Research Satellite (UARS) [PDF]

, 2003
The Microwave Limb Sounder (MLS) on Upper Atmosphere Research Satellite (UARS) is sensitive to water vapor and ozone in the lower stratosphere. The Cryogenic Limb Array Etalon Spectrometer (CLAES), another of the instruments on UARS, has a spatial and ...
Billingham, A., Harwood, R. S., Clark, H. L., Pumphrey, H. C.   +3 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source