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Urothelial carcinomas of the upper urinary tract

, 2017
Upper urinary tract urothelial carcinomas (UTUCs) are scarce and account for only 5-10% of urothelial carcinomas. The estimated annual incidence in western countries is approximately two new cases per 100,000 inhabitants. The natural history of UTUCs differs from that of bladder cancer; 60% of UTUCs are invasive at diagnosis compared to only 15% of ...
Tarek P. Ghoneim, Pierre Colin, Morgan Rouprêt   +2 more
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Contemporary Issues in Urothelial Carcinoma of Upper Urinary Tract

Advances in Anatomic Pathology, 2023
Upper urinary tract urothelial carcinoma (UTUC) is an uncommon malignancy involving the renal pelvis and ureter. Careful pathologic analysis plays a critical role in the diagnosis and clinical management of UTUC. In combination with clinical and radiologic evaluation, pathologic features can be used to stratify patients into low-risk and high-risk ...
Jianping, Zhao, Charles C, Guo, Priya, Rao   +2 more
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Upper urinary tract urothelial carcinoma

2023
Abstract Upper tract urothelial carcinoma (UTUC), although rarer than urothelial carcinoma of the bladder, is more aggressive with 60% of patients presenting with invasive disease. Bilateral synchronous UTUC is scarcer still, with much literature quoting a 2% lifetime risk of recurrence in the contralateral upper tract. This case aims to
Richard Nobrega, Mark Sullivan
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Treatment of upper urinary tract urothelial carcinoma

Surgical Oncology, 2011
Upper urinary tract urothelial carcinoma (UUTUC) is relatively rare, occurring in only 5% of all urothelial cancers. It has not been as extensively studied and reviewed as carcinoma of the bladder. UUTUC has a propensity for multifocality, local recurrence, and development of metastases, which argues for an aggressive treatment approach.
Guiyang, Cai, Xuefeng, Liu, Bin, Wu
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Management of upper urinary tract urothelial carcinoma

Expert Review of Anticancer Therapy, 2010
Upper urinary tract urothelial carcinoma (UTUC) is relatively uncommon. In this article, we review prognostic factors, criteria and indications for treatment with the available modalities using contemporary data. A systematic search on PubMed was performed using the keywords 'upper tract urothelial carcinoma', 'upper tract transitional cell carcinoma',
Maxine, Sun, Al'a, Abdo, Firas, Abdollah, Jan, Schmitges, Rodolphe, Thuret, Claudio, Jeldres, Shahrokh F, Shariat, Paul, Perrotte, Pierre I, Karakiewicz   +8 more
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[Urothelial carcinoma of the upper urinary tract].

Urologie (Heidelberg, Germany), 2023
Urothelial carcinoma of the upper urinary tract (upper tract urothelial carcinoma, UTUC) is less common than bladder carcinoma with nearly identical risk factors and has a poorer prognosis. The standard diagnostic procedure is imaging of the upper urinary tract by computed tomography urography.
Jennifer, Kranz, Marco, Hoffmann, Radu, Alexa, Christoph, Kuppe, Nadine Therese, Gaisa, Matthias, Saar   +5 more
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The Molecular Signature for Urothelial Carcinoma of the Upper Urinary Tract

Journal of Urology, 2008
Frequent loss of heterozygosity of microsatellites on a specific chromosomal region has been reported in various types of human cancer. The same loss of heterozygosity has also been identified in matched serum or urine DNA. We determined a urine microsatellite marker profile specific to urothelial carcinoma of the upper urinary tract.We analyzed the ...
Chung-Liang, Ho, Tzong-Shin, Tzai, Jung-Chin, Chen, Hung-Wen, Tsai, Hong-Lin, Cheng, Claus F, Eisenberger, Nan-Haw, Chow   +6 more
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Expression of p53 in upper urinary tract urothelial carcinoma

Nature Reviews Urology, 2011
The management of upper urinary tract urothelial carcinoma (UUT-UC) is controversial. Radical nephroureterectomy is a major undertaking and has obvious shortcomings in the presence of renal impairment and solitary kidneys, whereas endoscopic management can be associated with a risk of disease progression.
Stephen, Mitchell, Erik, Mayer, Anup, Patel   +2 more
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Endoscopic Management of Upper Urinary Tract Urothelial Carcinoma

Journal of Endourology, 2018
Endoscopic management of upper tract urothelial carcinoma has become more popular over the last few decades as there has been an impetus for renal preservation in these patients. While radical nephroureterectomy has been the gold standard in treatment of this disease, ureteroscopic and percutaneous management has become a viable option for select ...
Patrick, Samson, Arthur D, Smith, David, Hoenig, Zeph, Okeke   +3 more
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Prognostic factors for upper urinary tract urothelial carcinoma

Nature Reviews Urology, 2011
Upper urinary tract urothelial carcinoma (UTUC) is a rare disease, which means there are little evidence-based data available to guide clinical decision-making. Although diagnosis and treatment of UTUC have improved significantly over the last 5 years, accurate risk stratification remains a challenge owing to the difficulty of clinical staging.
Chromecki T. F., Bensalah K., Remzi M., Verhoest G., Cha E. K., Scherr D. S., Novara G., Karakiewicz P. I., Shariat S. F.   +8 more
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