Results 41 to 50 of about 135,079 (261)

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

open access: yesAdvanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang   +6 more
wiley   +1 more source

Solvent‐Induced Structural Modulation in Nanoscale Covalent Organic Frameworks Enables High‐Performance NO2 Sensing

open access: yesAngewandte Chemie, EarlyView.
Solvent intercalation disrupts the stacking order of protonated porphyrin‐based 2D COF nanoparticles, resulting in a less compactly packed structure with increased accessibility of porphyrin sites. This structural modulation leads to significantly enhanced chemiresistive NO2 sensing performance.
Yu Pan   +4 more
wiley   +2 more sources

Adapting International Business Models for EU Projects: Macro- and Micro-Foundations of the Uppsala Model in Multinational Collaborations

open access: yesBusinesses
This study examines the adaptation of the Uppsala Model to enhance the management of European Union (EU)-funded projects, particularly focusing on the macro- and micro-foundational elements of the model.
Cheryl Marie Cordeiro, Erik Sindhøj
doaj   +1 more source

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

open access: yesAdvanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias   +23 more
wiley   +1 more source

CO2‐to‐CO Electrochemical Conversion With an Fe(I) Porphyrin Complex in Water

open access: yesAngewandte Chemie, EarlyView.
Using in situ UV–vis/IR spectroelectrochemistry, we track CO2 reduction by a water‐soluble iron porphyrin. Rather than the usual [Fe0] intermediate in organic solvents, CO2 binds the electrogenerated [FeI] species and undergoes reductive C─O cleavage to stable [FeII‐CO]. This previously unexplored reaction pathway is facilitated by an aqueous H‐bonding
Andrew Howe   +5 more
wiley   +2 more sources

Book reviews

open access: yesScandinavian Journal of Disability Research, 2009
'From Institutional Life to Community Participation. Ideas and Realities Concerning Support to Persons with Intellectual Disability' . Ericsson Kent Acta Universitatis Upsaliensis. Uppsala Studies in Education.
Mårten Söder, Mårten Söder
doaj   +1 more source

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

open access: yesAdvanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan   +9 more
wiley   +1 more source

Nanoparticulate Quillaja saponin induces apoptosis in human leukemia cell lines with a high therapeutic index

open access: yesInternational Journal of Nanomedicine, 2010
Kefei Hu1, Saideh Berenjian1, Rolf Larsson2, Joachim Gullbo2, Peter Nygren3, Tanja Lövgren4, Bror Morein11Department of Medical Sciences, Section of Virology, Uppsala University, Uppsala, Sweden; 2Department of Medical Sciences, Uppsala ...
Kefei Hu   +3 more
doaj  

A Large Scale Multi‐Modal Workflow for Battery Characterization: From Concept to Implementation

open access: yesAdvanced Energy Materials, EarlyView.
Isolated characterization techniques produce independent datasets and single‐property insights. However, progressively more holistic interpretations of battery‐material behavior is needed in the future. Here we demonstrate a coordinated multimodal workflow enabling the correlation of heterogeneous datasets and the construction of multidimensional ...
François Cadiou   +34 more
wiley   +1 more source

Swedish Consumers' Willingness‐to‐Pay for Plant‐Based Proteins in Pasta Sauce: Preferences and Policy Scenarios

open access: yesAgribusiness, EarlyView.
ABSTRACT This paper explores Swedish consumers' protein preferences by estimating the willingness‐to‐pay (WTP) for minced meat and plant‐based proteins in pasta sauce from an in‐store experiment (n = 206) and an online discrete choice experiment (n = 517). On average, the WTP was highest for minced meat.
Emilia Mattsson   +3 more
wiley   +1 more source

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