Results 71 to 80 of about 145,867 (288)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Artivistic interventions as humorous re-appropriations

open access: yesThe European Journal of Humour Research, 2015
The article reflects on the synergic interaction of artistic creativity and activist engagement through a humorous approach of some contemporary civilian protest actions in Slovenia.
Aldo Milohnic
doaj  

Poland in the Period of Partitions 1795–1914 [PDF]

open access: yes, 2015
The present book “Poland – History, Culture and Society. Selected Readings” is the third edition of a collection of academic texts written with the intention to accompany the module by providing incoming students with teaching materials that will assist ...
Żurawski vel Grajewski, Radosław
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Lutyšský elekt dobývá Lutych. Příspěvek ke vztahům měst a vládnoucích elit ve středověkém Nizozemí [PDF]

open access: yesHistorie - Otázky - Problémy, 2020
This paper focuses on the complicated relations between medieval towns and the ruling elites in what is now Belgium and the Netherlands. It is illustrated by the uprising that broke out against the local elected bishop John III of Bavaria in Liège and ...
Zuzana Bolerazká
doaj  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

How to Reflect Zangids Uprising (255-270 AH) in Tabari History [PDF]

open access: yesپژوهش های تاریخی
The Zangids Uprising stands as one of the most significant movements in the mid-third century Hijri within the Abbasid Caliphate. Tabari's historical accounts serve as the primary and foundational source for understanding the events surrounding this ...
Bahador Shahriary, Abolghasem Foroozani
doaj   +1 more source

Home - About - Disclaimer - Privacy