RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
To Ignore, to Join in, or to Intervene? Contextual and Individual Factors Influencing Cyber Bystanders' Response to Cyberbullying Incidents. [PDF]
Arató N, Németh L, Macaulay PJR.
europepmc +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Low power and high-speed quadrate node upset tolerant latch design using CNTFET. [PDF]
Asiya S, S SK.
europepmc +1 more source
Cable/Antenna Bounds Connecting Field Levels To Personnel Safety And Electronic Upset Thresholds
William L. Langston +4 more
openalex +2 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Emotion regulation strategies among young men in rural areas and urban informal settlements in South Africa: a qualitative exploratory study. [PDF]
Nyoni P, Tomita A, Mkhwanazi S, Gibbs A.
europepmc +1 more source
Hazard criteria for wake vortex encounters [PDF]
A piloted, motion-base simulation was conducted to evaluate the ability of simulators to produce realistic vortex encounters and to develop criteria to define hazardous encounters.
Sammonds, R. I., Stinnett, G. W., Jr.
core +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Understanding Age-Based Differences in Psychosocial Harms, Physical Harms, and Access Difficulties Among an International Sample of Men Who Use Anabolic-Androgenic Steroids. [PDF]
Bonenti B +8 more
europepmc +1 more source

