Results 121 to 130 of about 14,080 (252)

Epigenetically Regulated NOX4/NRF2 Axis Mediates PM2.5‐Induced Ferroptosis and Inflammatory Response in Membranous Nephropathy

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT This study aims to explore the involvement and mechanism of ferroptosis in particulate matter 2.5 (PM2.5)–induced membranous nephropathy (MN) progression. A cationic bovine serum albumin (cBSA)–induced mouse model of MN was established, followed by PM2.5 exposure.
Yanhong Gao   +8 more
wiley   +1 more source

Synthesis of uracil derivatives by oxidation of Fischer tungsten–carbene uracil complexes

open access: yes, 2007
A study on the oxidation of Fischer tungsten-carbene uracil complexes has been carried out. Several commonly used oxidants gave results strongly influenced by the presence of substituent on nitrogen atoms.
DELLA SALA, Giorgio   +3 more
core   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

A unique uracil-DNA binding protein of the uracil DNA glycosylase superfamily

open access: yes, 2015
Uracil DNA glycosylases (UDGs) are an important group of DNA repair enzymes, which pioneer the base excision repair pathway by recognizing and excising uracil from DNA.
Sang, Pau Biak   +9 more
core   +1 more source

Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori   +9 more
wiley   +1 more source

HERPES-SIMPLEX VIRUS TYPE-1 URACIL-DNA GLYCOSYLASE - ISOLATION AND SELECTIVE-INHIBITION BY NOVEL URACIL DERIVATIVES

open access: yes, 1993
We have purified Herpes simplex type 1 (HSV1) uracil-DNA glycosylase from the nuclei of HSV1-infected HeLa cells harvested 8 h post-infection, at which time the induction of the enzyme is a maximum.
GAMBINO J   +5 more
core  

Acidity of a Nucleotide Base:  Uracil

open access: yes, 2016
Experiment and calculations are used to show that the gas-phase acidity of uracil is comparable to that of HCl. The gas-phase acidity of uracil (denoted here by U) was bracketed by proton-transfer measurements involving U and various reference acids ...
Thomas M. Miller (2302165)   +3 more
core   +1 more source

Beyond a dual role: how Purpureocillium lilacinum reprograms citrus metabolism for integrated biocontrol and growth promotion

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Plants harbor complex microbial communities that are fundamental to their health and productivity. Among them, endophytic fungi such as Purpureocillium lilacinum establish mutualistic associations, offering dual benefits as plant growth promoters and biocontrol agents.
Sana Bouzembila   +5 more
wiley   +1 more source

A NINE-MONTH CHRONIC TOXICITY STUDY OF TEGAFUR-URACIL MIXTURE (UFT) IN DOGS

open access: yes, 1988
In order to evalute the long-term-safety of UFT which contained tegafur [1-(2-tetrahydrofuryl)-5-fluorouracil, FT-207] and uracil in molar ratio of 1:4, a nine-month chronic toxicity study was performed in dogs. In doses of 9.7 (as FT-207 : 3mgkg), 16.2 (
Ariyoshi, Toshihiko   +5 more
core  

Tautomerism of uracil probed via IR spectroscopy of singly hydrated uracil.

open access: yes, 2008
International audienceTautomerism of the nucleobase uracil is characterized in the gas phase through IR photodissociation spectroscopy of singly hydrated protonated uracil created with tandem mass spectrometric methods in a commercially available Fourier
Salpin, Jean-Yves   +5 more
core   +1 more source

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