Results 111 to 120 of about 76,412 (252)

A novel Cas12b cytosine base editor enables efficient C‐to‐T base editing in the rice genome

Journal of Integrative Plant Biology, EarlyView.
The base editor dAaCas12b accurately induces C‐to‐T mutations in rice. It recognizes unique TTTV DNA motifs with a wider editing window, and its optimized guide RNA boosts efficiency, expanding crop gene‐editing resources.
Yulei Wei, Lin He, Jienan Han, Shengnan Ge, Xueheyuan Wang, Xinyu Liu, Jie Deng, Haiyang Zhang, Xinyang Che, Jianfeng Weng, Wujun Ma, Jingyu Xu   +11 more
wiley   +1 more source

Structural basis for uracil removal from DNA by human SMUG1. [PDF]

Nat Commun
Ludäscher JM, Scaletti Hutchinson E, Vila-Julià G, Jemth AS, Shahid S, Wiita E, Cabeza de Vaca I, Pach S, Gajdos L, Aggarwal S, Walse E, Mortusewicz O, Helleday T, Carlsson J, Stenmark P.   +14 more
europepmc   +1 more source

Engineered Yarrowia lipolytica inducing gene silencing confers control ability against gray mold in plants

Journal of Integrative Plant Biology, EarlyView.
Engineered the plant‐colonizing yeast Yarrowia lipolytica to produce and deliver double‐stranded RNAs targeting key genes of the gray mold fungus Botrytis cinerea produced a ‘living factory’ that continuously synthesizes and releases gene‐silencing molecules on plant surfaces, effectively suppressing the pathogen.
Mengjie Liu, Heng Shen, Jie Li, Mei Hao, Yelei Sun, Wenxing Liang   +5 more
wiley   +1 more source

Cadmium inhibits hSMUG1-mediated uracil excision: quantitative analysis and mitigation by <i>Ganoderma lucidum</i> extracts. [PDF]

J Enzyme Inhib Med Chem
Chang HL, Fang CH, Chang HL, Lee YF, Hsu WL, Chang JH, Chien MH, Goodman SD, Chang SY, Fang WH, Su KY.   +10 more
europepmc   +1 more source

Evaluation of Torula Yeast (Candida utilis) Single Cell Proteins as a Partial Replacement for Soybean Meal in Broiler Diets: Effects on Productive Performance, Meat Quality Traits, and Plasma Metabolome

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Over recent years the use of yeast in feedstuffs has gained momentum due to novel developments in single‐cell proteins (SCPs). SCPs are considered a sustainable protein source, as their production enable to convert low‐value substrates (including industrial/agricultural wastes) into feed, with a related reduced environmental impact. This study
Jonathan Dayan, Marco Zampiga, Francesca Soglia, Luca Laghi, Elisa Benini, Massimiliano Petracci, Federico Sirri   +6 more
wiley   +1 more source

Genetic analysis of pyrimidine biosynthetic enzymes in Plasmodium falciparum. [PDF]

PLoS Pathog
Rajaram K, Sievert ML, Elahi R, Blauwkamp J, Dillard LB, Absalon S, Prigge ST.   +6 more
europepmc   +1 more source

Nutrient disturbance in a shallow aquaculture pond impacts Microcystis gene expression but does not impact bacterial community function during bloom conditions

Journal of Phycology, EarlyView.
Abstract Cyanobacterial harmful algal blooms (cHABs) are worldwide issues. Reduced nitrogen forms (ammonium and urea) have recently been measured in freshwater systems at concentrations not previously recorded. These reduced nitrogen forms have been shown to favor the proliferation of harmful cyanobacteria.
Matthew F. Gladfelter, Hunter R. Baylous, Alan E. Wilson, Morgan M. Steffen   +3 more
wiley   +1 more source

Nanobody-based analysis of RhoGTPase stress response in <i>Schizosaccharomyces pombe</i>: Role of <i>mtl</i>2. [PDF]

Biotechnol Rep (Amst)
Rasheed N, Ali X, Ali T, Muhammad F, Rasheed MA.   +4 more
europepmc   +1 more source

The Dual‐Function of CtrNAC019‐CtrNPF2.1 Module in Salt Tolerance and Nitrogen Use Efficiency Via Enhancing Vacuolar Chloride Sequestration and Nitrate Efflux in Citrus trifoliata

Plant Biotechnology Journal, EarlyView.
ABSTRACT Salt stress and nitrogen utilisation efficiency (NUE) represent critical constraints affecting worldwide crop productivity. While nitrate transporter proteins (NPFs) have been implicated in saline chloride (Cl−) ion transport, the mechanistic linkage between chloride stress and NUE remains poorly understood.
Zeqi Zhao, Chengwei Yang, Xiangming Shang, Mengdi Li, Xiaoyang Su, Ji‐Hong Liu, Chunlong Li   +6 more
wiley   +1 more source

Cell‐Specific Expression and Cellular Compartmental Regulation in Camptothecin Biosynthesis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant secondary metabolites such as monoterpenoid indole alkaloids (MIAs) show tightly regulated biosynthesis and accumulation in specific organelles of distinct cell types. However, the cell‐specific expression patterns of anticancer MIA camptothecin biosynthetic genes in Ophiorrhiza pumila and the regulatory mechanisms of camptothecin ...
Xiaolong Hao, Yinkai Yang, Tiantian Chen, Xiaoxuan Fan, Yiqing Peng, Qingyan Ruan, Qin Zhou, Fanghao Liu, Jiayi He, Yongpeng Li, Yue Feng, Jiyan Qi, Guoyin Kai   +12 more
wiley   +1 more source