Results 91 to 100 of about 86,414 (313)
Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision
, 2019 Uracil DNA glycosylases (UDGs) are important DNA repair enzymes that excise uracil from DNA, yielding an abasic site. Recently, UdgX, an unconventional UDG with extremely tight binding to DNA containing uracil, was discovered.
Woo, Eui-Jeon +19 more
core +1 more source
Uracil moieties in Plasmodium falciparum genomic DNA [PDF]
, 2018 Plasmodium falciparum parasites undergo multiple genome duplication events during their development. Within the intraerythrocytic stages, parasites encounter an oxidative environment and DNA synthesis necessarily proceeds under these circumstances.
G. Vértessy, Beáta +9 more
core +1 more source
Journal of Raman Spectroscopy, EarlyView.Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira +3 more
wiley +1 more source
Frontiers in Chemistry, 2019 Substituted xanthine derivatives are important bioactive molecules. Herein we report on a new, practical synthesis of 6-amino-5-carboxamidouracils, the main building blocks for the preparation of 8-substituted xanthines, by condensation of 5,6 ...
Daniel Marx +4 more
doaj +1 more source
, 2021 A facile and reliable fluorescence method for the quantification of urinary uracil concentration is pro-posed herein. The assay utilizes a specific fluorescence (FL) derivatization reaction for uracil using 3-methyl-benzamidoxime as a ...
Sakurai, Hiroki +7 more
core +1 more source
Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security
Journal of the Science of Food and Agriculture, EarlyView.Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori +9 more
wiley +1 more source
, 2016 Uracil DNA glycosylase (UNG) is an important DNA repair enzyme that recognizes and excises uracil bases in DNA using an extrahelical recognition mechanism.
Lauren Seiple (13505) +3 more
core +1 more source
International Journal of Chemical Kinetics, EarlyView.ABSTRACT In the interstellar medium, chemical reactions proceed under conditions vastly different to those on Earth; these include extremely low temperatures and densities and take place in the gas phase and on water–ice grains. Understanding the energetics and more importantly the kinetics of such reactions is of relevance to the consequences on how ...
Judith Wurmel, John M. Simmie
wiley +1 more source
Register-Shifted Structures in Base-Flipped Uracil-Damaged DNA
, 2023 We report the occurrence of register-shifted structures in simulations of uracil-containing dsDNA. These occur when the 3′ base vicinal to uracil is thymine in U:A base-paired DNA.
Paul B. Orndorff (16006658) +3 more
core +1 more source
International Journal of Chemical Kinetics, EarlyView.ABSTRACT Recent experiments by Nunes et al. have demonstrated that unprecedented control of chemical reactions is possible by narrowband infrared vibrational photo‐excitation at low temperatures in inert matrices. The generated higher energy level conformers may then undergo rotamerisation and tautomerisation reactions which provide extremely useful ...
Judith Wurmel, John M. Simmie
wiley +1 more source