Results 71 to 80 of about 86,414 (313)
Annals of Gastroenterological Surgery, EarlyView.This study aimed to determine whether immuno‐nutritional and inflammatory markers could serve as predictors of the outcomes of postoperative adjuvant chemotherapy for stage III colorectal cancer in elderly patients. Postoperative lymphocyte‐to‐monocyte ratio and postoperative C‐reactive protein‐to‐albumin ratio accurately predicted the efficacy of ...
Tomoya Tago +6 more
wiley +1 more source
Chicken MBD4 Regulates Immunoglobulin Diversification by Somatic Hypermutation
Frontiers in Immunology, 2019 Immunoglobulin (Ig) diversification occurs via somatic hypermutation (SHM) and class switch recombination (CSR), and is initiated by activation-induced deaminase (AID), which converts cytosine to uracil.
Ryan Costello +2 more
doaj +1 more source
, 1996 Two enzymes, dUTP pyrophosphatase and uracil-DNA glycosylase, prevent the misincorporation of uracil into the genome in distinct manners. The atomic structures of these proteins complexed with substrate analogs reveal the structural basis for uracil ...
Vassylyev, Dmitry G, Morikawa, Kosuke
core +1 more source
KHẢO SÁT THÀNH PHẦN HÓA HỌC CỦA TRÁI KHỔ QUA (MOMORDICA CHARANTIA L.)
Tạp chí Khoa học Đại học Cần Thơ, 2011 Từ trái Khổ qua, hai chất: uracil (chất I, Hình 1) và momordicoside K (chất II, Hình 2) đã được cô lập từ cao ethyl acetate. Hai chất này được xác định bằng các phương pháp phổ hiện đại và so sánh với tài liệu đã công bố.
Ngô Hải Đăng +2 more
doaj
Uracil Compounds As Inhibitors For Glutamate Oxaloactate Tansaminase (GOT) In Serum Of Some Leukemia Patients [PDF]
Kirkuk Journal of Science, 2015 Effect of Uracil’s derivatives on enzyme glutamate oxaloacetate transaminase (GOT) for sample of normal human and some types of leukemia patients, acute lymphatic(ALL) (11 cases), acute mylosyticl (AML) (4 cases), acute mylomonocyticl (AMOL) (2cases ...
Nadia Q. Haj
doaj +1 more source
, 2015 The authors gratefully acknowledge EaStCHEM for computer time on the EaStCHEM Research Computing Facility. LFH is grateful to the Engineering and Physical Sciences Research Council for studentship support through the Doctoral Training Account scheme ...
van Mourik, Tanja +1 more
core +1 more source
A Modular Nucleoside Kinase Cascade for the Synthesis of Ribonucleoside Triphosphates
Biotechnology and Bioengineering, EarlyView.Damm et al. report standardized enzymatic cascades for production of all canonical nucleoside triphosphates from the corresponding nucleosides, using kinase‐catalyzed phosphorylation from acetyl phosphate. Reactions afforded ∼ 100 mM product in near‐quantitative conversion.
Oliver T. Damm +3 more
wiley +1 more source
Electrochemical fluorination of uracil
, 1980 In view of the importance of the medical applications of fluorinated uracil and derivatives, synthetic methods directed to obtain such compounds are of particular interest.
FRACCARO C. +9 more
core +1 more source
Identification of novel genes regulating the development of the palate
Developmental Dynamics, EarlyView.Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2015 An intramolecular dehydrogenative C–H activation enabled an efficient synthesis of an uracil-annulated β-carbolinone ring system. The reaction is simple, efficient and high yielding (85–92%).
Biplab Mondal +3 more
doaj +1 more source