Results 81 to 90 of about 139,089 (266)

Unwinding of primer-templates by archaeal family-B DNA polymerases in response to template-strand uracil [PDF]

, 2013
Archaeal family-B DNA polymerases bind tightly to deaminated bases and stall replication on encountering uracil in template strands, four bases ahead of the primer-template junction. Should the polymerase progress further towards the uracil, for example,
Allan, Aller, Anita C. Jones, Bandwar, Beechem, Beese, Bernard A. Connolly, Bloom, Brautigam, Brian J. Keith, Connolly, Connolly, Connolly, Datta, Emptage, Evans, Firbank, Fogg, Gill, Greagg, Guest, Hariharan, Hogg, Hogg, Jean, Joyce, Joyce, Keith, Killelea, Law, McCullough, Neely, Neely, Pauline Heslop, Record, Reha-Krantz, Reha-Krantz, Reid, Russell, Shamoo, Shuttleworth, Stivers, Stivers, Stocki, Subuddhi, Tomas T. Richardson, Trzenecka, Xiaohua Wu, Youngblood   +48 more
core   +1 more source

Impact of Body Weight Loss During Preoperative Chemoradiotherapy on Prognosis of Patients With Lower Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
The present study aimed to investigate the relationship between changes in body weight and composition during chemoradiotherapy, such as the psoas muscle mass index, visceral fat index, and subcutaneous fat index obtained from computed tomography images, and long‐term outcomes in rectal cancer patients.
Shinya Abe, Hiroaki Nozawa, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Yuichiro Yokoyama, Yuzo Nagai, Yuzo Harada, Takahide Shinagawa, Soichiro Ishihara   +9 more
wiley   +1 more source

KHẢO SÁT THÀNH PHẦN HÓA HỌC CỦA TRÁI KHỔ QUA (MOMORDICA CHARANTIA L.)

Tạp chí Khoa học Đại học Cần Thơ, 2011
Từ trái Khổ qua, hai chất: uracil (chất I, Hình 1) và momordicoside K (chất II, Hình 2) đã được cô lập từ cao ethyl acetate. Hai chất này được xác định bằng các phương pháp phổ hiện đại và so sánh với tài liệu đã công bố.
Ngô Hải Đăng, Nguyễn Ngọc Hạnh, Phùng Văn Trung   +2 more
doaj  

Uracil Compounds As Inhibitors For Glutamate Oxaloactate Tansaminase (GOT) In Serum Of Some Leukemia Patients [PDF]

Kirkuk Journal of Science, 2015
Effect of Uracil’s derivatives on enzyme glutamate oxaloacetate transaminase (GOT) for sample of normal human and some types of leukemia patients, acute lymphatic(ALL) (11 cases), acute mylosyticl (AML) (4 cases), acute mylomonocyticl (AMOL) (2cases ...
Nadia Q. Haj
doaj   +1 more source

Relationship Between the Product of Pre‐Treatment Neutrophil and Monocyte Counts and Clinical Outcomes in Rectal Cancer With Suspected Lateral Lymph Node Metastasis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim A novel systemic inflammatory response marker, the neutrophil × monocyte value (NM value), has been identified as a negative predictive factor for responses to chemoradiotherapy in rectal cancer. However, the clinical implications of the NM value remain unknown.
Takayoshi Sasaki, Shinya Abe, Hiroaki Nozawa, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Yuichiro Yokoyama, Yuzo Nagai, Yuzo Harada, Soichiro Ishihara   +9 more
wiley   +1 more source

Low energy electron scattering from DNA and RNA bases: shape resonances and radiation damage

, 2005
Calculations are carried out to determine elastic scattering cross sections and resonance energies for low energy electron impact on uracil and on each of the DNA bases (thymine, cytosine, adenine, guanine), for isolated molecules in their equilibrium ...
Blackburn G. M., Chris H. Greene, Levesque P., Parr R. G., Stefano Tonzani   +4 more
core   +1 more source

Novel inhibition of archaeal family-D DNA polymerase by uracil. [PDF]

, 2013
International audienceArchaeal family-D DNA polymerase is inhibited by the presence of uracil in DNA template strands. When the enzyme encounters uracil, following three parameters change: DNA binding increases roughly 2-fold, the rate of polymerization ...
Connolly, Bernard A, Gilroy, Louise, Henneke, Ghislaine, Ishino, Yoshizumi, Richardson, Tomas T   +4 more
core   +2 more sources

Artificial Intelligence for Multiscale Modeling in Solid‐State Physics and Chemistry: A Comprehensive Review

Advanced Intelligent Systems, EarlyView.
This review explores the transformative impact of artificial intelligence on multiscale modeling in materials research. It highlights advancements such as machine learning force fields and graph neural networks, which enhance predictive capabilities while reducing computational costs in various applications.
Artem Maevskiy, Vitalii Kapitan, Andrey Ustyuzhanin   +2 more
wiley   +1 more source

Synthesis of new dipeptides based on uracil and thymine and investigation of the molecular docking of these compounds as inhibitors of quorum sensing system in Pseudomonas aeruginosa [PDF]

شیمی کاربردی روز, 2019
In this study, due to the importance of dipeptide compounds in diagnosis of disease or as drug compounds, new dipeptide compounds were synthesized using pyrimidine derivatives of thymine and uracil.
Azam Heidari, Nazila Valikhani fard, Nader Noshiranzadeh, Rahman Bikas   +3 more
doaj   +1 more source

Gas Phase Structure and Reactivity of Doubly Charged Microhydrated Calcium(II)-Catechol Complexes Probed by Infrared Spectroscopy [PDF]

, 2014
Doubly charged microhydrated adducts formed from catechol and calcium(II) were produced in the gas phase using electrospray ionization (ESI) appearing as the most important ions in the mass spectra recorded. The gas phase structures of [Ca(catechol)2(H2O)
Arroyo Mañez, Pau, Butler, Matias, Cabrera, Gabriela Myriam, Phillipe Maître   +3 more
core   +1 more source