Results 1 to 10 of about 60,577 (273)

Thymines opposite to bulky aristolactam-DNA adducts in duplex DNA are not targeted by human thymine-DNA glycosylase [PDF]

PeerJ
Background Consumption of aristolochic acids (AA) from the plant Aristolochia results in the formation of bulky aristolactam-dA (dA-AL) and aristolactam-dG (dG-AL) adducts in cellular DNA ultimately leading to the development of urothelial cancer ...
Diana Manapkyzy, Gulzhan Zhamanbayeva, Viktoriya Sidorenko, Radha Bonala, Francis Johnson, Bakhyt T. Matkarimov, Dmitry Zharkov, Murat K. Saparbaev, Sabira Taipakova   +8 more
doaj   +2 more sources

Lack of Association Between Toll-like Receptor 2 Polymorphisms (R753Q and A-16934T) and Atopic Dermatitis in Children from Thrace Region of Turkey

Balkan Medical Journal, 2017
Background: Atopic dermatitis is the most common chronic inflammatory skin disease. A complex interaction of both genetic and environmental factors is thought to contribute to the disease. Aims: To evaluate whether single nucleotide polymorphisms in the
Ceren Can, Mehtap Yazıcıoğlu, Hakan Gürkan, Hilmi Tozkır, Adnan Görgülü, Necdet Hilmi Süt   +5 more
doaj   +1 more source

Isolation of acetylcholinesterase gene from Egyptian Anopheles pharoensis (Theobald)

Journal of Basic and Applied Zoology, 2012
Acetylcholinesterase (ACE) is the target of two major insecticide families, organophosphates (OPS) and carbamates. Acetylcholinesterase is a frequent resistance mechanism in insects and responsible mutations were identified in many dipteran species.
Nahla M. Wassim
doaj   +1 more source

Joining Nanotubes Comprising Nucleobase-carrying Amphiphilic Polypeptides

CHIMIA, 2018
Three kinds of amphiphilic polypeptides, X-poly(sarcosine)-b-(L-Leu-Aib)6 (X = adenine, thymine, glycolic acid), were synthesized and self-assembled in a tris buffer to take on nanotube morphology.
Toru Itagaki, Yuna Ueda, Kenji Itabashi, Hirotaka Uji, Shunsaku Kimura   +4 more
doaj   +1 more source

Interactions of some metal ions with Nitrogenous bases present in Nucleotides

مجلة بغداد للعلوم, 2007
Acidity constants at 30co and 0.125 ionic strength have been determined for the Nitrogous bases of nucleic acid; cytocine, uarcil and thymine, and found to be 3.55 x10-19 , 1.44 x10 -19 and 7.24 x10 -20 respectively.
Baghdad Science Journal
doaj   +1 more source

Laser flash photolysis and magnetic-field-effect studies on interaction of thymine and thymidine with menadione: role of sugar in controlling reaction pattern

Science and Technology of Advanced Materials, 2008
The magnetic field effect (MFE) in conjunction with laser flash photolysis has been used for the study of the interaction of one of the small drug like quinone molecules, 2-methyl, 1,4-naphthoquinone, commonly known as menadione (MQ), with one of the DNA
Adity Bose, Debarati Dey and Samita Basu
doaj  

Stabilization of Long-Looped i-Motif DNA by Polypyridyl Ruthenium Complexes

Frontiers in Chemistry, 2019
A spectroscopic study of the interactions of Λ- and Δ-[Ru(phen)2(dppz)]2+ with i-motif DNA containing thymine loops of various lengths. In the presence of i-motifs, the luminescence of the Λ enantiomer was enhanced much more than the Δ. Despite this, the
Benjamin J. Pages, Sarah P. Gurung, Sarah P. Gurung, Kane McQuaid, Kane McQuaid, James P. Hall, James P. Hall, Christine J. Cardin, John A. Brazier   +8 more
doaj   +1 more source

Fully Supramolecular Polyrotaxanes as Biphase Drug Delivery Systems

International Journal of Polymer Science, 2014
Pseudopolyrotaxanes (PPR) consisting of α-cyclodextrin rings and polyethylene glycol axes with end thymine groups have been synthesized and characterized successfully.
Abdolhossien Massoudi, Mohsen Adeli, Leila Khosravi far   +2 more
doaj   +1 more source

Uso da 99mTc-Timina na identificação de metástases de tumor venéreo transmissível canino com apresentação cutânea The use of 99mTc-Thymine to identify metastatic disease in dogs presenting the cutaneous form of canine transmissible venereal tumor

Pesquisa Veterinária Brasileira, 2008
O tumor venéreo transmissível canino (TVTC) é descrito na literatura como raramente metastático. Entretanto, métodos acurados para verificação dessa afirmativa não estão disponíveis na rotina veterinária.
Paulo S.M. Castelo-Branco, Sergio A. Lopes de Souza, Flávia P.P. Lobo Lopes, Verônica Castro, Priscila Sena, João Batista Pereira, Lea M. Barbosa da Fonseca, Bianca Gutfilen   +7 more
doaj   +1 more source

Programmable DNA pyrimidine base editing via engineered uracil-DNA glycosylase

Nature Communications
DNA base editing technologies predominantly utilize engineered deaminases, limiting their ability to edit thymine and guanine directly. In this study, we successfully achieve base editing of both cytidine and thymine by leveraging the translesion DNA ...
Zongyi Yi, Xiaoxue Zhang, Xiaoxu Wei, Jiayi Li, Jiwu Ren, Xue Zhang, Yike Zhang, Huixian Tang, Xiwen Chang, Ying Yu, Wensheng Wei   +10 more
doaj   +1 more source