Results 41 to 50 of about 65,002 (285)
Micromachines, 2020 In this study, we developed a modified glassy carbon electrode (GCE) with graphene oxide, multi-walled carbon nanotube hybrid nanocomposite in chitosan (GCE/GO-MWCNT-CHT) to achieve simultaneous detection of four nucleobases (i.e., guanine (G), adenine ...
Shuting Wang +3 more
doaj +1 more source
, 2012 A novel functional monomer T-IPTS, 3-isocyanatopropyltriethoxysilane (IPTS) bearing thymine (T) bases, was synthesized for imprinting Hg2+. Then a novel Hg2+ ionic imprinted polymers (IIPs) based on thymine-Hg2+-thymine (T-Hg2+-T) interactions, i.e.
Xu, Shoufang +9 more
core +1 more source
PLoS ONE, 2022 IntroductionThymine auxotrophic in vitro mutants of Escherichia coli were first reported in the mid-20th century. Later, thymine-dependent clinical strains of E. coli as well as other Enterobacterales, Enterococcus faecalis and Staphylococcus aureus have
Aleksandra Jakovljev +6 more
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Molecules, 2014 The regioisomeric cycloadducts of bromonitrile oxide and N-benzoyl-2,3-oxaza-norborn-5-ene were easily prepared and elaborated into a novel class of uracil-based scaffolds. The key-synthetic step is the nucleophilic substitution at the sp2 carbon atom of
Misal Giuseppe Memeo +3 more
doaj +1 more source
Optical Detection of Cellular Signals at Material Interfaces
Advanced Healthcare Materials, EarlyView.Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren +5 more
wiley +1 more source
The contribution of thymine--thymine interactions to the stability of folded dimeric quadruplexes [PDF]
Nucleic Acids Research, 1997 The loop of four thymines in the sodium form of the dimeric folded quadruplex [d(G3T4G3)]2 assumes a well-defined structure in which hydrogen bonding between the thymine bases appears to contribute to the stability and final conformation of the quadruplex.
M A, Keniry, E A, Owen, R H, Shafer
openaire +2 more sources
Iterative Selection of DNA Nanostructures for Cellular Uptake
Advanced Materials, EarlyView.DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar +4 more
wiley +1 more source
Spectroscopic Evaluation of Novel Adenine/Thymine-Conjugated Naphthalenediimides: Preference of Adenine-Adenine over Thymine-Thymine Intermolecular Hydrogen Bonding in Adenine- and Thymine-Functionalized Naphthalenediimides [PDF]
, 2019 The synthesis and spectroscopic characterization of novel nucleobase (adenine/thymine)-conjugated naphthalenediimides (NDIs), namely, NDI-AA, NDI-TT, and NDI-AT have been successfully achieved. NDI-AA, NDI-TT and NDI-AT have similar absorption in the 300–
Neouchy, Zeina +6 more
core +1 more source
Dynamic Operations in Macromolecular Data Storage
Angewandte Chemie, EarlyView.With the exponential growth of digital data and the limitations of conventional silicon‐based storage and computing technologies, macromolecular data storage, the practice of encoding digital information within large, complex molecules like DNA or synthetic polymers, has emerged as a scalable and sustainable alternative to traditional digital ...
Jakub Ossowski +3 more
wiley +2 more sources