Results 31 to 40 of about 60,531 (292)

Synthesis of Cyclobutane Analogue 4: Preparation of Purine and Pyrimidine Carbocyclic Nucleoside Derivatives

open access: yesMolecules, 2019
The coupling of 2-bromo-3-benzoyloxycyclobutanone with purine under basic conditions produces two regioisomers consisting of the N-7 and N-9 alkylated products in equal amounts in their racemic forms.
Noha Hasaneen   +8 more
doaj   +1 more source

Molecular Characterisation of Orf Virus in Goats From Eastern Türkiye. [PDF]

open access: yesVet Med Sci
This study provides the molecular characterisation of Orf virus (ORFV) strains circulating in Türkiye. Phylogenetic analysis of F1L, B2L, and VIR genes reveals high genetic similarity with Asian and global isolates, highlighting the importance of multi‐gene analysis in monitoring viral outbreaks and understanding disease origins.
Özbek R, Ilgın M, Can-Şahna K.
europepmc   +2 more sources

Novel Hg2+-imprinted polymers based on thymine–Hg2+–thymine interaction for highly selective preconcentration of Hg2+ in water samples

open access: yes, 2012
A novel functional monomer T-IPTS, 3-isocyanatopropyltriethoxysilane (IPTS) bearing thymine (T) bases, was synthesized for imprinting Hg2+. Then a novel Hg2+ ionic imprinted polymers (IIPs) based on thymine-Hg2+-thymine (T-Hg2+-T) interactions, i.e.
Xu, Shoufang   +9 more
core   +1 more source

Low-energy Electron Collisions with Gas-phase Thymine Molecule

open access: yesMedžiagotyra, 2011
The paper presents an investigation of the negative ion formation of the thymine (T) molecule. The formation of negative ions by electron impact of this molecule is measured.
Irina V. CHERNYSHOVA   +4 more
doaj   +1 more source

Simultaneous Determination of Four DNA bases at Graphene Oxide/Multi-Walled Carbon Nanotube Nanocomposite-Modified Electrode

open access: yesMicromachines, 2020
In this study, we developed a modified glassy carbon electrode (GCE) with graphene oxide, multi-walled carbon nanotube hybrid nanocomposite in chitosan (GCE/GO-MWCNT-CHT) to achieve simultaneous detection of four nucleobases (i.e., guanine (G), adenine ...
Shuting Wang   +3 more
doaj   +1 more source

Phenotypic and genotypic characterisation of thymine auxotrophy in Escherichia coli isolated from a patient with recurrent bloodstream infection.

open access: yesPLoS ONE, 2022
IntroductionThymine auxotrophic in vitro mutants of Escherichia coli were first reported in the mid-20th century. Later, thymine-dependent clinical strains of E. coli as well as other Enterobacterales, Enterococcus faecalis and Staphylococcus aureus have
Aleksandra Jakovljev   +6 more
doaj   +1 more source

The contribution of thymine--thymine interactions to the stability of folded dimeric quadruplexes [PDF]

open access: yesNucleic Acids Research, 1997
The loop of four thymines in the sodium form of the dimeric folded quadruplex [d(G3T4G3)]2 assumes a well-defined structure in which hydrogen bonding between the thymine bases appears to contribute to the stability and final conformation of the quadruplex.
M A, Keniry, E A, Owen, R H, Shafer
openaire   +2 more sources

A mutant of uracil DNA glycosylase that distinguishes between cytosine and 5-methylcytosine

open access: yes, 2014
We demonstrate that a mutant of uracil DNA glycosylase (N123D:L191A) distinguishes between cytosine and methylcytosine. Uracil DNA glycosylase (UDG) efficiently removes uracil from DNA in a reaction in which the base is flipped into the enzyme’s active ...
Fox, Keith R.   +11 more
core   +1 more source

Spectroscopic Evaluation of Novel Adenine/Thymine-Conjugated Naphthalenediimides: Preference of Adenine-Adenine over Thymine-Thymine Intermolecular Hydrogen Bonding in Adenine- and Thymine-Functionalized Naphthalenediimides [PDF]

open access: yes, 2019
The synthesis and spectroscopic characterization of novel nucleobase (adenine/thymine)-conjugated naphthalenediimides (NDIs), namely, NDI-AA, NDI-TT, and NDI-AT have been successfully achieved. NDI-AA, NDI-TT and NDI-AT have similar absorption in the 300–
Neouchy, Zeina   +6 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

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