Photoinduced Formation Mechanism of the Thymine–Thymine (6–4) Adduct [PDF]
The photoinduced mechanism leading to the formation of the thymine-thymine (6-4) photolesion has been studied by using the CASPT2//CASSCF approach over a dinucleotide model in vacuo. Following light absorption, localization of the excitation on a single thymine leads to fast singlet-triplet crossing that populates the triplet (3)(nπ*) state of thymine.
Daniel Roca-Sanjuán +2 more
exaly +6 more sources
A colorimetric probe based on a hybrid sensing system of gold nanoparticles (AuNPs), silver nanoparticles (AgNPs), and thymine (Thy) was developed for easy and rapid detection of copper (II) ions (Cu2+) in solution. The underlying principle of this probe
Thitiporn Thongkam +4 more
doaj +1 more source
Thymine-Modified Silicones: A Bioinspired Approach to Cross-Linked, Recyclable Silicone Polymers [PDF]
In DNA, thymine typically forms hydrogen bonds with adenine to hold two complementary strands together and to preserve the genetic code. While thymine is typically absent in RNA, a thymine–thymine hydrogen bonding structure is reminiscent of the wobble ...
Paul M. Zelisko +5 more
core +1 more source
The reaction of mer-(Ru(H)2(CO)(PPh3)3) (1) with one equivalent of thymine acetic acid (THAcH) unexpectedly produces the macrocyclic dimer k1(O), k2(N,O)-(Ru(CO)(PPh3)2THAc)2 (4) and, concomitantly, the doubly coordinated species k1(O), k2(O,O)-(Ru(CO ...
Silvia Bordoni +7 more
doaj +1 more source
Thymine Sensitizes Gram-Negative Pathogens to Antibiotic Killing
Diminished antibiotic susceptibility of bacterial pathogens is an increasingly serious threat to human and animal health. Alternative strategies are required to combat antibiotic refractory bacteria.
Yuan Liu +10 more
doaj +1 more source
Thymine-Induced Dynamic Switching of Self-Assembled Nanofibers in Diaminotriazine-Functionalized Tetraphenylethylene Derivatives: Implications for One-Dimensional Molecular Devices [PDF]
One-dimensional (1D) supramolecular polymers of aggregation-induced emission (AIE)-active chromophores belong to an in-demand group of functional materials because of their potential applications in optoelectronic devices like optical waveguides, lasers,
Sajena K. Saraswathi +3 more
core +1 more source
Sensitive Silver-Enhanced Microplate Apta-Enzyme Assay of Sb3+ Ions in Drinking and Natural Waters
The toxic effects of antimony pose risks to human health. Therefore, simple analytical techniques for its widescale monitoring in water sources are in demand. In this study, a sensitive microplate apta-enzyme assay for Sb3+ detection was developed.
Nadezhda S. Komova +4 more
doaj +1 more source
Tautomerisation Mechanisms in the Adenine-Thymine Nucleobase Pair During DNA Strand Separation [PDF]
The adenine-thymine tautomer (A*-T*) has previously been discounted as a spontaneous mutagenesis mechanism due to the energetic instability of the tautomeric configuration.
Max, Winokan +5 more
core +1 more source
The exploration of the ionic liquids’ mechanism of action on nucleobase’s structure and properties is still limited. In this work, the binding model of the 1-alkyl-3-methylimidazolium bromide ([Cnmim]Br, n = 2, 4, 6, 8, 10) ionic liquids to the thymine ...
Yanni Wang +7 more
doaj +1 more source
Mutagenicity of a unique thymine-thymine dimer or thymine-thymine pyrimidine pyrimidone (6-4) photoproduct in mammalian cells [PDF]
The mutagenic properties of UV-induced photoproducts, both the cis-syn thymine-thymine dimer (TT) and the thymine-thymine pyrimidine pyrimidone (6-4) photoproduct [T(6-4)T] were studied in mammalian cells using shuttle vectors. A shuttle vector able to replicate in both mammalian cells and bacteria was produced in its single-stranded DNA form. A unique
A, Gentil +5 more
openaire +2 more sources

