Thymine-Modified Nanocarrier for Doxorubicin Delivery in Glioblastoma Cells
Molecules, 2023 Brain tumor glioblastoma is one of the worst types of cancer. The blood–brain barrier prevents drugs from reaching brain cells and shields glioblastoma from treatment.
Albina Y. Ziganshina +10 more
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Prebiotic Route to Thymine from Formamide—A Combined Experimental–Theoretical Study
Molecules, 2021 Synthesis of RNA nucleobases from formamide is one of the recurring topics of prebiotic chemistry research. Earlier reports suggest that thymine, the substitute for uracil in DNA, may also be synthesized from formamide in the presence of catalysts ...
Lukáš Petera +12 more
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Adenine and Thymine Effect on Quartz Dissolution at Different Artificial Seawaters
Orbital: The Electronic Journal of Chemistry, 2018 According to Bernal (1951) minerals may have played important roles in the origin of life such as: protect biomolecules against degradation by UV radiation or hydrolysis, pre-concentrate biomolecules from prebiotic seas and formation of polymers.
Dimas Augusto Morozin Zaia +2 more
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Investigation of the spin-forbidden process in thymine [PDF]
Hemijska Industrija, 2012 The intersystem crossing rate from the lowest singlet to the lowest triplet state of thymine was studied by means of the ab initio methods. The rate was calculated employing the time-dependent approach based on the correlation function.
Etinski Mihajlo R.
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The behavior of triplet thymine in a model B-DNA strand. Energetics and spin density localization revealed by ab initio molecular dynamics simulations. [PDF]
, 2021 Among the natural occurring nucleobases, thymine presents the lowest triplet state, hence it represents a hotspot for energy transfer and photosensitization.
Elise, Dumont +2 more
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Novel Hg2+-imprinted polymers based on thymine–Hg2+–thymine interaction for highly selective preconcentration of Hg2+ in water samples [PDF]
, 2012 A novel functional monomer T-IPTS, 3-isocyanatopropyltriethoxysilane (IPTS) bearing thymine (T) bases, was synthesized for imprinting Hg2+. Then a novel Hg2+ ionic imprinted polymers (IIPs) based on thymine-Hg2+-thymine (T-Hg2+-T) interactions, i.e.
Xu, Shoufang +9 more
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Nanomaterials, 2017 Mercury ion (Hg2+) is recognized as one of the most toxic metal ions for the environment and for human health. Techniques utilized in the detection of Hg2+ are an important factor.
Hao Yang +8 more
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Synthesis of new dipeptides based on uracil and thymine and investigation of the molecular docking of these compounds as inhibitors of quorum sensing system in Pseudomonas aeruginosa [PDF]
شیمی کاربردی روز, 2019 In this study, due to the importance of dipeptide compounds in diagnosis of disease or as drug compounds, new dipeptide compounds were synthesized using pyrimidine derivatives of thymine and uracil.
Azam Heidari +3 more
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A mutant of uracil DNA glycosylase that distinguishes between cytosine and 5-methylcytosine [PDF]
, 2014 We demonstrate that a mutant of uracil DNA glycosylase (N123D:L191A) distinguishes between cytosine and methylcytosine. Uracil DNA glycosylase (UDG) efficiently removes uracil from DNA in a reaction in which the base is flipped into the enzyme’s active ...
Fox, Keith R. +11 more
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