Results 51 to 60 of about 65,002 (285)
Incorporation of Thymine into Prototrophic and Thymine-dependent Mutants of Bacillus anthracis [PDF]
Journal of General Microbiology, 1969 SUMMARY: Mutants of Bacillus anthracis which were prototrophic in a defined medium below 32° required either thymidine (mutant thy) or low concentration of thymine (mutant thytlr) for growth at 37°. No thymidylate synthetase was produced by these mutants at 37°. Normal enzyme activity was found in bacteria grown at 25°.
Ivánovics, György +2 more
openaire +3 more sources
Advanced Science, EarlyView.A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li +9 more
wiley +1 more source
Flavin Catalysts in Organic Synthesis
Angewandte Chemie, EarlyView.Flavins and their congeners are potent catalysts for organic synthesis inspired by enzymatic transformations. In addition to catalysis in the flavin ground state via covalent intermediates, the excited singlet and triplet states unlock applications including photooxidation, photoreduction, and energy transfer via sensitization.
Jan Freudenberg, Golo Storch
wiley +2 more sources
Advanced Science, EarlyView.ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo +16 more
wiley +1 more source
Photoinduced Formation Mechanism of the Thymine–Thymine (6–4) Adduct
, 2016 The photoinduced mechanism leading to the formation of the thymine–thymine (6–4) photolesion has been studied by using the CASPT2//CASSCF approach over a dinucleotide model in vacuo.
Angelo Giussani (1753096) +4 more
core +1 more source
pH‐Driven Actuation of Unmodified DNA Origami Rectangles
Angewandte Chemie, EarlyView.Unmodified DNA origami rectangles exhibit a reversible transition between planar and tubular states driven by near‐neutral pH changes. This behavior arises from crossover‐mediated mechanical coupling of overwound DNA and extends to dimers and nanoribbons, enabling the formation of nanotube architectures without added motifs or chemical modification ...
Diego A. Uehara +4 more
wiley +2 more sources
Synthesis and Characterization of Thymine-15N2
Journal of Isotopes, 2016 A novel and mild synthesis method of thymine-15N2 was designed. Ethyl formate and ethyl propionate as raw materials, the intermediate ethyl 2-formylpropionate was condensed under sodium metal, the target compound thymine-15N2 was obtained by condensation
XU Jian-fei +3 more
doaj +1 more source
Expression and the Peculiar Enzymatic Behavior of the Trypanosoma cruzi NTH1 DNA Glycosylase. [PDF]
PLoS ONE, 2016 Trypanosoma cruzi, the etiological agent of Chagas' disease, presents three cellular forms (trypomastigotes, epimastigotes and amastigotes), all of which are submitted to oxidative species in its hosts. However, T.
Fernando Ormeño +10 more
doaj +1 more source
Time Resolved DNA Barcodes for Information Encoding and Dynamic Encryption
Advanced Science, EarlyView.This study establishes a molecular information platform based on DNA Temporal Barcodes. Information is encoded through combinations of DNA tags with distinct retention times, while dynamic encryption is achieved through a key‐triggered DNA ligation.
Likang Chu +7 more
wiley +1 more source
Preparation of Thymine Dinucleotide Methylphosphonate Analogs via Thymine Methylphosphonofluoridate
, 2016 Preparation of Thymine Dinucleotide Methylphosphonate Analogs via Thymine ...
N. Chidambaram (3035982) +1 more
core +1 more source