Results 51 to 60 of about 60,577 (273)

Low-energy Electron Collisions with Gas-phase Thymine Molecule

open access: yesMedžiagotyra, 2011
The paper presents an investigation of the negative ion formation of the thymine (T) molecule. The formation of negative ions by electron impact of this molecule is measured.
Irina V. CHERNYSHOVA   +4 more
doaj   +1 more source

Simultaneous Determination of Four DNA bases at Graphene Oxide/Multi-Walled Carbon Nanotube Nanocomposite-Modified Electrode

open access: yesMicromachines, 2020
In this study, we developed a modified glassy carbon electrode (GCE) with graphene oxide, multi-walled carbon nanotube hybrid nanocomposite in chitosan (GCE/GO-MWCNT-CHT) to achieve simultaneous detection of four nucleobases (i.e., guanine (G), adenine ...
Shuting Wang   +3 more
doaj   +1 more source

Phenotypic and genotypic characterisation of thymine auxotrophy in Escherichia coli isolated from a patient with recurrent bloodstream infection.

open access: yesPLoS ONE, 2022
IntroductionThymine auxotrophic in vitro mutants of Escherichia coli were first reported in the mid-20th century. Later, thymine-dependent clinical strains of E. coli as well as other Enterobacterales, Enterococcus faecalis and Staphylococcus aureus have
Aleksandra Jakovljev   +6 more
doaj   +1 more source

Oxidatively Damaged Nucleobases in Duplex DNA Oligomers: Reaction at Thymine−Thymine Mispairs [PDF]

open access: yes, 2016
Oxidatively Damaged Nucleobases in Duplex DNA Oligomers: Reaction at Thymine−Thymine ...
Joshy Joseph (1494178)   +1 more
core   +1 more source

The contribution of thymine--thymine interactions to the stability of folded dimeric quadruplexes [PDF]

open access: yesNucleic Acids Research, 1997
The loop of four thymines in the sodium form of the dimeric folded quadruplex [d(G3T4G3)]2 assumes a well-defined structure in which hydrogen bonding between the thymine bases appears to contribute to the stability and final conformation of the quadruplex.
M A, Keniry, E A, Owen, R H, Shafer
openaire   +2 more sources

Thymine-D2 [PDF]

open access: yes, 2017
Inelastic Neutron Scattering spectrum of Thymine-D2, C₅H₄D₂O₂N₂, measured on the TFXA ...
H. Jobic, CNRS Ville
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spectroscopic Evaluation of Novel Adenine/Thymine-Conjugated Naphthalenediimides: Preference of Adenine-Adenine over Thymine-Thymine Intermolecular Hydrogen Bonding in Adenine- and Thymine-Functionalized Naphthalenediimides [PDF]

open access: yes, 2019
The synthesis and spectroscopic characterization of novel nucleobase (adenine/thymine)-conjugated naphthalenediimides (NDIs), namely, NDI-AA, NDI-TT, and NDI-AT have been successfully achieved. NDI-AA, NDI-TT and NDI-AT have similar absorption in the 300–
Neouchy, Zeina   +6 more
core   +1 more source

Three-Dimensional Heterocycles: New Uracil-Based Structures Obtained by Nucleophilic Substitution at the sp2 Carbon of Bromoisoxazoline

open access: yesMolecules, 2014
The regioisomeric cycloadducts of bromonitrile oxide and N-benzoyl-2,3-oxaza-norborn-5-ene were easily prepared and elaborated into a novel class of uracil-based scaffolds. The key-synthetic step is the nucleophilic substitution at the sp2 carbon atom of
Misal Giuseppe Memeo   +3 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

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