Results 51 to 60 of about 60,531 (292)
Preparation of Thymine Dinucleotide Methylphosphonate Analogs via Thymine Methylphosphonofluoridate
Preparation of Thymine Dinucleotide Methylphosphonate Analogs via Thymine ...
N. Chidambaram (3035982) +1 more
core +1 more source
Conformationally controlled, thymine-based alpha-nucleopeptides [PDF]
Rigid peptide backbones and backbone-to-side chain H-bonds permit the design of a-nucleopeptides with known 3D-structure; thymine–thymine base pairing is also ...
GEOTTI BIANCHINI P +7 more
core +1 more source
Optimization of SWCNT‐FET Biosensors by Aptamer Engineering and Toehold‐Mediated Strand Displacement
Aptamer‐based single‐walled carbon nanotube (SWCNT) field‐effect transistor (FET) biosensors are developed for label‐free, real‐time biomarker detection. Truncated DNA aptamers enhance sensitivity through improved conformational switching. A toehold‐mediated strand displacement (TMSD) strategy optimizes functionalization and simplifies fabrication. The
Haosen Miao +8 more
wiley +1 more source
Synthesis and Characterization of Thymine-15N2
A novel and mild synthesis method of thymine-15N2 was designed. Ethyl formate and ethyl propionate as raw materials, the intermediate ethyl 2-formylpropionate was condensed under sodium metal, the target compound thymine-15N2 was obtained by condensation
XU Jian-fei +3 more
doaj +1 more source
Context-Dependent Photodimerization in Isolated Thymine−Thymine Steps in DNA
Context-Dependent Photodimerization in Isolated Thymine−Thymine Steps in ...
Frederick D. Lewis (1278270) +1 more
core +1 more source
Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang +10 more
wiley +1 more source
Inelastic Neutron Scattering spectrum of Thymine, C₅H₆N₂O₂, measured on the TFXA ...
H.Jobic, CNRS, Lyons, France
core +1 more source
Ascorbic Acid‐Engineered Interface Enables Universal DNA Functionalization on Gold Nanoparticles: Attenuating electrostatic repulsion and leveraging synergistic hydrogen‐bonding interactions significantly lowers the kinetic barrier for DNA adsorption, enabling rapid and sequence‐general functionalization of non‐thiolated DNA‐requiring only a single ...
Guangping Li +9 more
wiley +1 more source
Eco‐friendly enzymatic synthesis of high‐fidelity, site‐specifically modified DNA using 3′‐blocked nucleotides for full synthetic control and next‐generation sequencing compatibility. ABSTRACT Methods for site‐specific incorporation of modified DNA building blocks remain limited.
Raveena Raveena +2 more
wiley +1 more source
Association of a Homozygous TYMP c.131G>C Variant With MNGIE in a Chinese Pedigree: Insights From Genetic Analysis and Computational Modeling. [PDF]
Researcher highlight: Extending beyond the recently reported compound heterozygous case, we report the same TYMP c.131G>C variant in a homozygous configuration, delivering key genetic evidence for its standalone pathogenicity in MNGIE. ABSTRACT Background Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive disorder ...
Li L +6 more
europepmc +2 more sources

