Results 71 to 80 of about 106,654 (267)

Electron scattering from molecules and molecular aggregates of biological relevance [PDF]

, 2017
In this Topical Review we survey the current state of the art in the study of low energy electron collisions with biologically relevant molecules and molecular clusters.
Allan M, Allan M, Bouchiha D, Calegari F, Caprasecca S, Colyer C J, Colyer C J, da Costa R F, Denifl S, Dora A, Dubernet M L, Fabrikant I I, Fabrikant I I, Ferlay J, Fujimoto M M, Hall E, Herbert J M ed Parrill A L, Jensen F, Jimena D Gorfinkiel, Keller A, Linert I, Marangos J P, Nikjoo H, Ryszka M, Samukawa S, Slaughter D S, Surko C M, Sylwia Ptasinska, Trevisan C S, Vizcaino V, Winstead C, Zecca A, Zubek M, Ómarsson B   +33 more
core   +1 more source

Macrophage Phenotype Detection Methodology on Textured Surfaces via Nuclear Morphology Using Machine Learning

Advanced Intelligent Discovery, EarlyView.
A novel machine learning approach classifies macrophage phenotypes with up to 98% accuracy using only nuclear morphology from DAPI‐stained images. Bypassing traditional surface markers, the method proves robust even on complex textured biomaterial surfaces. It offers a simpler, faster alternative for studying macrophage behavior in various experimental
Oleh Mezhenskyi, Kateryna Andriienkova, Tetyana Goldanova, Ezgi Antmen, Thibaut Soubrie, Nihal Engin Vrana   +5 more
wiley   +1 more source

A Highly Sensitive and Selective Competition Assay for the Detection of Cysteine Using Mercury-Specific DNA, Hg2+ and Sybr Green I

Sensors, 2011
We here report a rapid, sensitive, selective and label-free fluorescence detection method for cysteine (Cys). The conformation of mercury-specific DNA (MSD) changes from a random coil form to a hairpin structure in the presence of Hg2+ due to the ...
Gang Liu, Lihua Wang, Jingwen Chen, Shuzhen Ren, Dun Pan, Quanwen Liu, Hui Xu, Shuli Gao, Min Ding   +8 more
doaj   +1 more source

Tight-binding parameters for charge transfer along DNA

, 2009
We systematically examine all the tight-binding parameters pertinent to charge transfer along DNA. The $\pi$ molecular structure of the four DNA bases (adenine, thymine, cytosine, and guanine) is investigated by using the linear combination of atomic ...
A. Holmen, A. Migliore, A. Rakitin, A.A. Voityuk, A.A. Voityuk, A.F. Fucaloro, A.J. Storm, A.L. Sobolewski, A.O. Colson, B. Giese, B. Mennucci, C. Simserides, C.A. Sprecher, C.J. Burrows, Ch. Adesi, Ch. Adesi, D. Dougherty, D. Hennig, D. Hennig, D. Porath, D. Varsano, D. Voet, D.B. Hall, D.W. Miles, E. Diaz, E. Meggers, F. Zaloudek, F.C. Grozema, G. Kalosakas, G. Kalosakas, G. Kalosakas, G. Kalosakas, G. Lauer, G.P. Triberis, G.P. Triberis, H. Mehrez, H. Sugiyama, H. Zhang, H.W. Fink, J. Lin, J. Lin, J. Lorentzon, J.B. MacNaughton, J.C. Slater, K. Keren, K. Raksanyi, K. Senthilkumar, K.-H. Yoo, L. Blancafort, L. Cai, L. G. D. Hawke, L.B. Clark, L.B. Clark, L.G.D. Hawke, L.G.D. Hawke, M. Fuentes-Cabrera, M. Fuentes-Cabrera, M. Fuentes-Cabrera, M. Hutter, M. Menon, M. Menon, M.K. Shukla, M.K. Shukla, M.K. Shukla, M.K. Shukla, M.P. Fülscher, M.P. Fülscher, M.R. Arkin, M.R. Singh, N. Ismail, N. Lathiotakis, N. Rosch, N.C. Seeman, N.S. Hush, P. Maniadis, P. Maniadis, P. Maragakis, P. Tran, P.B. Woiczikowski, P.J. Dandliker, P.J. de Pablo, P.T. Henderson, R. Bruinsma, R. Di Felice, R.G. Endres, S. Komineas, S. Urano, S.R. Rajski, S.S. Mallajosyula, S.V. Rakhmanova, T. Cramer, T. Fleig, T. Kubar, T. Yamada, W. Voelter, W. Zhang, W.C. Brunner, X. Li, X. Li, Y. Matsuoka, Y. Zhang, Y.-J. Ye, Y.A. Berlin, Y.A. Berlin, Z. Kutnjak, Z.G. Yu   +105 more
core   +1 more source

Majority‐Voting Overlapping Method for Error Correction in DNA Data Storage

Advanced Intelligent Discovery, EarlyView.
We propose an overlapping‐based majority‐voting method for DNA data storage error correction. By aligning multiple reads and choosing the most frequent base per position, it suppresses substitution errors without prior models. Validated on synthetic and real sequencing data, it achieves high‐fidelity, scalable, and cost‐effective reconstruction ...
Thi Bich Ngoc Nguyen, Seongjun Seo, Anshula Tandon, Nguyen Kim Uyen, Thi Hong Nhung Vu, Sung Ha Park   +5 more
wiley   +1 more source

A TDDFT study of the excited states of DNA bases and their assemblies [PDF]

, 2006
We present a detailed study of the optical absorption spectra of DNA bases and base pairs, carried out by means of time dependent density functional theory.
Di Felice, R., Marques, M. A. L., Rubio, A., Varsano, D.   +3 more
core   +2 more sources

Heterogenous Model of Temozolomide Resistance in Glioblastoma Reveals Phenotypic Shifts in Drug Response and Migratory Potential

Advanced NanoBiomed Research, EarlyView.
Glioblastoma mortality is driven by cell invasion and therapeutic resistance. We report a cancer engineering approach to evaluate the behavior of heterogeneous cohorts of temozolomide resistant and responsive GBM cells. We show the effect of physiologically‐relevant metronomic dosing on ensemble drug response and invasion.
Victoria A. Kriuchkovskaia, Ela K. Eames, Sydney A. McKee, Paul J. Hergenrother, Rebecca B. Riggins, Brendan A. C. Harley   +5 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy

Chemistry – A European Journal, EarlyView.
Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez, Robby Büchner, Mattis Fondell, Albert M. Brouwer   +3 more
wiley   +1 more source

Multi-omic analysis of precocious puberty girls: pathway changes and metabolite validation

Frontiers in Endocrinology
ObjectivePrecocious puberty (PP) is a prevalent endocrine disorder affecting the physical and mental wellbeing of children. Identifying the triggering factors of PP has become a central issue.
Fang Zhou, Jianhong Mao, Zhenzhen Jin, Li Zhu, Xiaofang Li   +4 more
doaj   +1 more source