Results 81 to 90 of about 106,654 (267)

Thymineless Death, at the origin

open access: yesFrontiers in Microbiology, 2015
Thymineless death (TLD) in bacteria has been a focus of research for decades. Nevertheless, the advances in the last five years, with Escherichia coli as the model organism, have been outstanding.
Elena C Guzmán, Carmen eMartín
doaj   +1 more source

Effect of gas flow on electronic transport in a DNA-decorated carbon nanotube

open access: yes, 2011
We calculate the two-time current correlation function using the experimental data of the current-time characteristics of the Gas-DNA-decorated carbon nanotube field effect transistor.
Al’tshuler B L   +9 more
core   +1 more source

Revisiting C4N4 Fluorophore: Theoretical Elucidation of the Origin of Fluorescent Properties of 2,5‐Diaminopyrimidines and Strategic Applications to Pd Detection

open access: yesChemistry – A European Journal, EarlyView.
A compact C4N4 fluorophore—comprising only four carbons and four nitrogens—shows structure‐dependent fluorescence that can be rationalized by TDDFT and AFIR analyses. Rational structural design controls whether emission is turned ON or OFF through computationally identified CI structures.
Miki Kohei   +5 more
wiley   +1 more source

Electrosynthesis of PolyFilm Modified Graphite Electrode and its Application Towards Determination of Thymine [PDF]

open access: yesMaterials Research
This article presents an electrochemical sensor designed for the identification of thymine, one of the nitrogenous bases in deoxyribonucleic acid, crucial for diagnosing damage and health issues such as cancer.
M.P. Amaral   +3 more
doaj   +1 more source

C‐Terminal Nucleobase Modification Amplifies Peptide‐Mediated Liposome Fusion

open access: yesChemistry – A European Journal, EarlyView.
Let's come together right now. Cationic peptides are known to promote aggregation of negatively charged liposomes through electrostatic interaction. The process is reversible: once neutrality is achieved, liposomes disaggregate. Here, we demonstrate that end‐capping peptides with nucleobases turns the process into irreversible fusion.
Laura Morbiato   +4 more
wiley   +1 more source

Nucleobase pairing and photodimerization in a biologically derived metal-organic framework nanoreactor

open access: yesNature Communications, 2019
Metal-organic frameworks have shown promise as nanoreactors, facilitating the synthesis of molecules that are otherwise difficult to isolate. Here, the authors design a framework featuring unobstructed adenine linkers to which thymine molecules can base ...
Samantha L. Anderson   +10 more
doaj   +1 more source

Stretching of a single-stranded DNA: Evidence for structural transition

open access: yes, 2009
Recent experiments have shown that the force-extension (F-x) curve for single-stranded DNA (ssDNA) consisting only of adenine [poly(dA)] is significantly different from thymine [poly(dT)].
C. R. Cantor   +5 more
core   +1 more source

Click Capture SELEX for the Identification of Click‐Modified Aptamers Targeting Small Molecules in Solution

open access: yesChemistry – A European Journal, EarlyView.
Using kanamycin A as a model target, we developed click‐capture SELEX to identify nucleobase‐modified aptamers capable of binding small molecules in solution. This approach enables flexible incorporation of nucleobase modifications via CuAAC, allowing the chemical properties of the aptamer to be tailored to the target molecule.
Philipp Menke   +5 more
wiley   +1 more source

Boson Sampling for Molecular Vibronic Spectra

open access: yes, 2014
Quantum computers are expected to be more efficient in performing certain computations than any classical machine. Unfortunately, the technological challenges associated with building a full-scale quantum computer have not yet allowed the experimental ...
Aspuru-Guzik, Alán   +4 more
core   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer   +6 more
wiley   +1 more source

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