Results 101 to 110 of about 60,531 (292)

β‐Aminoisobutyric Acid Alleviates Cisplatin‐Induced Muscle Atrophy by Regulating E3 Ubiquitin Ligases, Apoptosis, Amino Acid Metabolism, Autophagy, and Ferroptosis

Medicine Bulletin, EarlyView.
ABSTRACT Background Cisplatin (CIS) is a widely used broad‐spectrum anticancer agent, but its clinical application is often limited by severe adverse effects, including skeletal muscle atrophy, which compromises patients' quality of life and treatment efficacy.
Hao‐Zhe Wang, Wen‐Bi He, Huan Wang, Hao Wang, Wen‐Jun Fang, Meng‐Qian Li, Jiong‐Xing Huang, Fei‐Peng Chen, Hui‐Guo Wang, Lin Zhu, Xiao‐Guang Liu   +10 more
wiley   +1 more source

Gamma-irradiation of thymine dimers in aqueous solution

, 1968
Thymine dimers were irradiated in aqueous solution with 60Co γ-rays in N2 or O2. Thymine and unidentified non-UV-absorbing products appeared. The thymine was identified by spectrophotometry, chromatography, and ability to support the growth of ...
Deering, R.A., Snipes, W., Snipes, Wallace   +2 more
core   +1 more source

Direct interaction between MreB and the RodA‐PBP2 complex organizes lateral cell wall synthesis in Escherichia coli

mLife, EarlyView.
Abstract The elongasome, or the Rod complex, orchestrates lateral peptidoglycan (PG) synthesis in many rod‐shaped bacteria. It consists of the actin‐like protein MreB, the PG synthase RodA‐PBP2 complex, as well as MreCD and RodZ. Although the loss or disruption of any elongasome component results in a loss of rod shape, previous studies found that a ...
Rui Zhan, Han Gong, Ying Li, Xiangdong Chen, Joe Lutkenhaus, Shishen Du   +5 more
wiley   +1 more source

Interactions of some metal ions with Nitrogenous bases present in Nucleotides

مجلة بغداد للعلوم, 2007
Acidity constants at 30co and 0.125 ionic strength have been determined for the Nitrogous bases of nucleic acid; cytocine, uarcil and thymine, and found to be 3.55 x10-19 , 1.44 x10 -19 and 7.24 x10 -20 respectively.
Baghdad Science Journal
doaj   +1 more source

Optical mapping reveals a higher level of large‐scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease

The Journal of Pathology, EarlyView.
Abstract Myotonic dystrophy type 1 (DM1) is a clinically challenging multisystem neuromuscular hereditary disorder, with generational increase in severity and earlier age at onset. It is caused by an unstable cytosine‐thymine‐guanine repeat expansion at the DMPK locus, accompanied by associated genetic and epigenetic modifications.
Md Mehedi Hasan, Jenna Craddock, Tingting Gong, Ruth J Lyons, Igor Stevanovski, Sanjog R Chintalaphani, Ira W Deveson, Weerachai Jaratlerdsiri, Kishore R Kumar, Vanessa M Hayes   +9 more
wiley   +1 more source

Laser flash photolysis and magnetic-field-effect studies on interaction of thymine and thymidine with menadione: role of sugar in controlling reaction pattern

Science and Technology of Advanced Materials, 2008
The magnetic field effect (MFE) in conjunction with laser flash photolysis has been used for the study of the interaction of one of the small drug like quinone molecules, 2-methyl, 1,4-naphthoquinone, commonly known as menadione (MQ), with one of the DNA
Adity Bose, Debarati Dey and Samita Basu
doaj  

Stabilization of Long-Looped i-Motif DNA by Polypyridyl Ruthenium Complexes

Frontiers in Chemistry, 2019
A spectroscopic study of the interactions of Λ- and Δ-[Ru(phen)2(dppz)]2+ with i-motif DNA containing thymine loops of various lengths. In the presence of i-motifs, the luminescence of the Λ enantiomer was enhanced much more than the Δ. Despite this, the
Benjamin J. Pages, Sarah P. Gurung, Sarah P. Gurung, Kane McQuaid, Kane McQuaid, James P. Hall, James P. Hall, Christine J. Cardin, John A. Brazier   +8 more
doaj   +1 more source

Multifunktionale DNA‐Moiré‐Supergitter: Moiré‐Strukturen aus den Bausteinen des Lebens

Physik in unserer Zeit, EarlyView.
Moiré‐Strukturen sind längst ein Schlüsselbegriff in der modernen Festkörperphysik. Sie entstehen, wenn sich zwei periodische Materialgitter mit leicht unterschiedlichen Gitterkonstanten oder Orientierungen übereinanderlagern. Das so entstehende großflächige Interferenzmuster, das als Moiré‐Muster bezeichnet wird, kann die physikalischen Eigenschaften ...
Andreas Peil, Xinxin Jing, Laura Na Liu
wiley   +1 more source

Fully Supramolecular Polyrotaxanes as Biphase Drug Delivery Systems

International Journal of Polymer Science, 2014
Pseudopolyrotaxanes (PPR) consisting of α-cyclodextrin rings and polyethylene glycol axes with end thymine groups have been synthesized and characterized successfully.
Abdolhossien Massoudi, Mohsen Adeli, Leila Khosravi far   +2 more
doaj   +1 more source

Uso da 99mTc-Timina na identificação de metástases de tumor venéreo transmissível canino com apresentação cutânea The use of 99mTc-Thymine to identify metastatic disease in dogs presenting the cutaneous form of canine transmissible venereal tumor

Pesquisa Veterinária Brasileira, 2008
O tumor venéreo transmissível canino (TVTC) é descrito na literatura como raramente metastático. Entretanto, métodos acurados para verificação dessa afirmativa não estão disponíveis na rotina veterinária.
Paulo S.M. Castelo-Branco, Sergio A. Lopes de Souza, Flávia P.P. Lobo Lopes, Verônica Castro, Priscila Sena, João Batista Pereira, Lea M. Barbosa da Fonseca, Bianca Gutfilen   +7 more
doaj   +1 more source