Results 91 to 100 of about 60,531 (292)

Human thymine DNA glycosylase (TDG) and methyl‐CpG‐binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair

open access: yes, 2003
The repair enzymes thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) remove thymines from T:G mismatches resulting from deamination of 5-methylcytosine.
Yoon, Jung‐Hoon   +3 more
core   +1 more source

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

open access: yesJournal of the Chinese Chemical Society, EarlyView.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

Isolation of acetylcholinesterase gene from Egyptian Anopheles pharoensis (Theobald)

open access: yesJournal of Basic and Applied Zoology, 2012
Acetylcholinesterase (ACE) is the target of two major insecticide families, organophosphates (OPS) and carbamates. Acetylcholinesterase is a frequent resistance mechanism in insects and responsible mutations were identified in many dipteran species.
Nahla M. Wassim
doaj   +1 more source

Conical Intersections in Thymine

open access: yes, 2016
The mechanisms which are responsible for the radiationless deactivation of the nπ* and ππ* excited singlet states of thymine have been investigated with multireference ab initio methods (the complete-active-space self-consistent-field (CASSCF) method and
Serhiy Perun (2515996)   +2 more
core   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

Joining Nanotubes Comprising Nucleobase-carrying Amphiphilic Polypeptides

open access: yesCHIMIA, 2018
Three kinds of amphiphilic polypeptides, X-poly(sarcosine)-b-(L-Leu-Aib)6 (X = adenine, thymine, glycolic acid), were synthesized and self-assembled in a tris buffer to take on nanotube morphology.
Toru Itagaki   +4 more
doaj   +1 more source

Kinetics of Thymine Photodimerization in DNA

open access: yes, 1963
The kinetics of thymine photodimerization in E. coli DNA have been measured at various wavelengths of ultraviolet light. The initial quantum yield is not strongly dependent on wavelength. The ratio of thymine dimer to thymine in the photostationary state
Wulff, Daniel L.
core   +1 more source

Chemical Kinetics of 2‐, 4‐, and 2,4‐Seleno‐Uracils at Low Temperatures: Tautomerizations and Rotamerizations on Inert Matrices

open access: yesInternational Journal of Chemical Kinetics, EarlyView.
ABSTRACT In the interstellar medium, chemical reactions proceed under conditions vastly different to those on Earth; these include extremely low temperatures and densities and take place in the gas phase and on water–ice grains. Understanding the energetics and more importantly the kinetics of such reactions is of relevance to the consequences on how ...
Judith Wurmel, John M. Simmie
wiley   +1 more source

Relaxation Dynamics of Hydrated Thymine, Thymidine, and Thymidine Monophosphate Probed by Liquid Jet Time-Resolved Photoelectron Spectroscopy

open access: yes, 2019
The relaxation dynamics of thymine and its derivatives thymidine and thymidine monophosphate were studied using time-resolved photoelectron spectroscopy applied to a water microjet. Two absorption bands were studied, the first is a bright ππ* state which
Erica, Liu   +5 more
core   +1 more source

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

open access: yesMacromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

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