Results 61 to 70 of about 106,654 (267)
Base composition of DNA in adenovirus-12-induced tumor [PDF]
, 1969 A series of experiments was conducted to study the base composition of DNA in AVl2-induced tumor and host cells by paper chromatography, and it was found that DNA per cent. guanine-cystosine contents were around 42 % in both of them. The base composition
Ohmori, Masaki
core +1 more source
CRISPR/Cas13a: Compensatory Target Activation Mechanism
Advanced Science, EarlyView.CRISPR/Cas13a‐CTAM as a novel compensatory target activation mechanism that enables synergistic activation of Cas13a via two independently editable short RNA effectors. This dual‐effector system maintains enzymatic activity comparable to traditional single‐effector while significantly enhancing flexibility, sensitivity, and application scope.
Bowen Jiang +8 more
wiley +1 more source
Purine and pyrimidine bases as growth substances for lactic acid bacteria [PDF]
, 1941 In 1936 Richardson (1) showed that uracil was essential for the anaerobic growth of Staphylococcus aureus, but not for aerobic growth of the same organism.
Mitchell, Herschel K., Snell, Esmond E.
core
Physisorption of Nucleobases on Graphene [PDF]
, 2007 We report the results of our first-principles investigation on the interaction of the nucleobases adenine (A), cytosine (C), guanine (G), thymine (T), and uracil (U) with graphene, carried out within the density functional theory framework, with ...
C. Klein +8 more
core +3 more sources
Mechanozyme: An Artificial Enzyme With a Mechanophore Framework
Advanced Science, EarlyView.Mechanical destabilization of a G‐quadruplex mechanophore in a DNAzyme markedly boosts its catalytic activity, demonstrating “mechanozymes” as artificial enzymes whose functions are modulated by mechanical stress exerted by ultrasonication. This mechanozyme principle is broadly applicable to control biomolecular activities.
Jiahao Ji +7 more
wiley +1 more source
First-principles GW calculations for DNA and RNA nucleobases
, 2011 On the basis of first-principles GW calculations, we study the quasiparticle properties of the guanine, adenine, cytosine, thymine, and uracil DNA and RNA nucleobases.
A. Travers +6 more
core +4 more sources
Optimization of SWCNT‐FET Biosensors by Aptamer Engineering and Toehold‐Mediated Strand Displacement
Advanced Science, EarlyView.Aptamer‐based single‐walled carbon nanotube (SWCNT) field‐effect transistor (FET) biosensors are developed for label‐free, real‐time biomarker detection. Truncated DNA aptamers enhance sensitivity through improved conformational switching. A toehold‐mediated strand displacement (TMSD) strategy optimizes functionalization and simplifies fabrication. The
Haosen Miao +8 more
wiley +1 more source
How Does Thymine DNA Survive Ultrafast Dimerization Damage?
Molecules, 2016 The photodimerization reaction between the two adjacent thymine bases within a single strand has been the subject of numerous studies due to its potential to induce DNA mutagenesis and possible tumorigenesis in human skin cells.
Hongjuan Wang, Xuebo Chen
doaj +1 more source
Mechanisms of base selection by the E.coli mispaired uracil glycosylase [PDF]
, 2008 The repair of the multitude of single-base lesions formed daily in the cells of all living organisms is accomplished primarily by the base-excision repair (BER) pathway that initiates repair through a series of lesion-selective glycosylases.
Darwanto, Agus +6 more
core +2 more sources
Correlation Dynamics and Enhanced Signals for Serial DNA Sequencing
, 2013 Nanopore based sequencing has demonstrated significant potential for the development of fast, accurate, and cost-efficient fingerprinting techniques for next generation molecular detection and sequencing.
Ahmed, Towfiq +5 more
core +1 more source