Results 131 to 140 of about 14,080 (252)

Size Matters: Barrier Heights and Widths in the Kinetics Of Tautomerisation and Rotamerisation of Thiotropolone and Its Five‐ and Three‐Membered Cyclic Analogues

open access: yesInternational Journal of Chemical Kinetics, EarlyView.
ABSTRACT Recent experiments by Nunes et al. have demonstrated that unprecedented control of chemical reactions is possible by narrowband infrared vibrational photo‐excitation at low temperatures in inert matrices. The generated higher energy level conformers may then undergo rotamerisation and tautomerisation reactions which provide extremely useful ...
Judith Wurmel, John M. Simmie
wiley   +1 more source

An excess electron connects uracil to glycine

open access: yes, 2003
In recent work Gutowski et al. [Eur. Phys. J. D 20, 431 (2002)] reported photoelectron–spectroscopy and theoretical study of covalent anion of the uracil–glycine complex.
L. Adamowicz   +2 more
core   +1 more source

Is DNA metabarcoding an option for formaldehyde‐preserved zooplankton time series?

open access: yesLimnology and Oceanography: Methods, EarlyView.
Abstract The recovery of amplifiable DNA from formaldehyde‐fixed (FF) zooplankton samples has long been considered problematic, but advances in degraded‐DNA retrieval have renewed interest in FF samples. To access the information stored in long‐term zooplankton time series, we evaluated methods for extracting amplifiable DNA from community samples ...
Aitor Albaina   +4 more
wiley   +1 more source

Uracil (5,6-D2)

open access: yes, 1997
Inelastic Neutron Scattering spectrum of Uracil (5,6-D2), C₄ H₂ D₂ N₂ O₂, measured on the TFXA ...
F.Fillaux, CNRS, Paris, France
core   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima   +6 more
wiley   +1 more source

Sodium Ions Affect GPR17 Conformational States and Functionality

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Sodium is an allosteric modulator of several class‐A GPCR regulating active versus inactive conformation state and may be a critical issue for the optimization of crystallization procedures. Herein, the role of Na+ in the regulation of GPR17 conformational states was studied through MD simulations of GPR17 wild‐type and mutated on two ...
Luca Palazzolo   +6 more
wiley   +1 more source

Molecular Basis for Uracil‐DNA‐Glycosylase to Identify DNA Damage in the Nucleosome

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The DNA base‐excision repair (BER) pathway is initiated by a glycosylase, such as uracil‐DNA‐glycosylase (UDG), which identifies and removes a wrong base incorporated in the DNA sequence. The very early steps in the identification of the DNA damage are crucial to the correct initiation of the repair chain, and become even more complex when ...
Safwen Ghediri   +2 more
wiley   +1 more source

RNA degradomics and proteomics reveal the mechanism of dsProsβ1‐mediated proteasome targeting in Psylliodes chrysocephala

open access: yesPest Management Science, EarlyView.
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden   +3 more
wiley   +1 more source

Synthesis and Biological Activities of Some Metal Complexes of 2-Thiouracil and Its Derivatives: A Review

open access: yesCompounds
The thionamide antithyroid agents were discovered largely through observations carried out by various researchers in the 1940s that found that sulfhydryl-containing substances were goitrogenic in animals. Prof. Edwin B.
Petja Emilova Marinova   +1 more
doaj   +1 more source

Effects of Hydrogen Bonding on the Acidity of Uracil

open access: yes, 2016
The present study uses density functional theory to investigate the effects of hydrogen bonding on the (N1) acidity of uracil. Uracil and uracil anion complexes with water, ammonia, and hydrogen fluoride at various uracil sites (O2(N3), O4(N3) and O4(C5))
Stacey D. Wetmore (696456)   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy