Results 291 to 300 of about 165,169 (375)

Genomic Uracil Homeostasis during Normal B Cell Maturation and Loss of This Balance during B Cell Cancer Development

open access: yesMolecular and Cellular Biology, 2014
Sophia Z. Shalhout   +6 more
semanticscholar   +1 more source

The Direct and Individual Transcriptional Function of the Human Homodimeric and Heterodimeric Basic Helix–Loop–Helix Transcription Factors E47 and Scleraxis

open access: yesThe FASEB Journal, Volume 39, Issue 12, 30 June 2025.
The isolated yeast model allowed visualization of the function of the heterodimeric SCX and E47 transcription factors (TFs) in the absence of other interacting proteins. The findings support the need for additional transcription factor binding sites (TFBS) and a permissive chromatin landscape for these TFs to exert a positive transcriptional effect ...
Karla Miranda López‐Delucio   +5 more
wiley   +1 more source

Efficacy of adjuvant tegafur-uracil (UFT) in early-stage non-small cell lung cancer with poor prognostic factors. [PDF]

open access: yesTransl Lung Cancer Res
Watanabe T   +6 more
europepmc   +1 more source

DFT‐Guided Synthesis, Electrochemical, and Photophysical Properties of Ruthenium(II) Polypyridyl Complexes Featuring Flavin‐Inspired π‐Extended Ligands

open access: yesChemistry – A European Journal, Volume 31, Issue 36, June 26, 2025.
The photophysical properties as well as the multielectron storage capacity of a several ruthenium(II) polypyridyl complexes with flavin‐inspired π‐extended ligands are investigated in a joint synthetic‐spectroscopic‐theoretical approach. Abstract Light‐driven electron transfer and subsequent multielectron storage is among the key aspects of ...
Nina Hagmeyer   +9 more
wiley   +1 more source

Organocatalytic Switches of DNA Glycosylase OGG1 Catalyze a Highly Efficient AP‐Lyase Function

open access: yesChemistry – A European Journal, Volume 31, Issue 33, June 12, 2025.
Organocatalytic switches are small molecules that combine active site affinity and a nitrogen‐centered base for catalysis, effectively removing the rate‐determining step of the OGG1 biochemical cascade. Here, we identify a minimal structure and modulate the active nitrogen pKa, enabling the catalysis of ultrafast AP site incisions in a range of pH ...
Mario Kehler   +28 more
wiley   +1 more source

Variations in Human Milk Metabolites After Gestational Diabetes: Associations with Infant Growth. [PDF]

open access: yesNutrients
Fradet A   +7 more
europepmc   +1 more source

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