Results 301 to 310 of about 165,169 (375)

Constant Enzymatic in situ Production of H2O2 for an Unspecific Peroxygenase by an l–Amino Acid Oxidase

Advanced Synthesis &Catalysis, Volume 367, Issue 11, June 3, 2025.
Abstract Unspecific Peroxygenases have been the subject of a lot of research in the recent past as they offer opportunities for green hydroxylation reactions using hydrogen peroxide (H2O2) as donor. A striking problem of UPOs is their low stability against their own co‐substrate H2O2. In order to prevent the deactivation, we developed an enzyme cascade
Simon Last, Tobias Heinks, Niklas Dietz, Simon Koopmeiners, Gabriele Fischer von Mollard, Martin J. Weissenborn, Jan von Langermann   +6 more
wiley   +1 more source

Anticoagulant effects, substance basis, and quality assessment approach of Aspongopus chinensis Dallas. [PDF]

PLoS One
Fu J, Zhang G, Peng H, Xu Z, Liu Y, Chen K, Li J.   +6 more
europepmc   +1 more source

Ring Transformation of Uracils to 2-Pyridones. Hydrolysis of 6-(2-dimethylaminovinyl)uracils

, 1978
Shigeo Senda, Kosaku Hirota, Tetsuji Asao, Yoshio Abe   +3 more
openalex   +1 more source

A New Case of Allergic Contact Dermatitis to Topical Simvastatin Used for Treatment of Porokeratosis

Contact Dermatitis, Volume 93, Issue 1, Page 73-75, July 2025.
Nadia Raison‐Peyron, Céline Girard, Manon Girod, Olivier Dereure   +3 more
wiley   +1 more source

Chemical Switching: A Concept Inspired by Strategies from Biocatalysis and Organocatalysis

ChemBioChem, Volume 26, Issue 11, June 3, 2025.
Chemical Switching is introduced as a novel technology that exploits the promiscuity of enzymatic transformations by applying small molecule organocatalytic switches (ORCAs) or gain‐of‐function protein variants. The modulation of underlying chemical principles thereby amplifies low‐rate or installs otherwise absent enzymatic activities to dominate ...
Torkild Visnes, Kaixin Zhou, Aurino M. Kemas, Dominic Campopiano, Volker M. Lauschke, Maurice Michel   +5 more
wiley   +1 more source

Exponential Clonal Expansion of 5-Fluorocytosine-Resistant Candida tropicalis and New Insights into Underlying Molecular Mechanisms. [PDF]

Emerg Infect Dis
Abou-Chakra N, Astvad KMT, Martinussen J, Munksgaard ASE, Arendrup MC.   +4 more
europepmc   +1 more source

Isoniazid‐Dihydropyrimidinone Molecular Hybrids: Design, Synthesis, Antitubercular Activity, and Cytotoxicity Investigations with Computational Validation

ChemMedChem, Volume 20, Issue 11, June 2, 2025.
Antitubercular evaluation of a novel library of isoniazid‐dihydropyrimidinone molecular hybrids (8a–8n) discloses a potent compound with MIC = 0.39μg mL−1 against M. tuberculosis mc26230. Cytotoxicity, stability, and in silico studies, including molecular docking and ADME/T (absorption, distribution, metabolism, excretion, and toxicity) analysis ...
Gobind Kumar, Pule Seboletswe, Sahil Mishra, Neha Manhas, Safiyah Ghumran, Nagaraju Kerru, Françoise Roquet‐Banères, Maëlle Foubert, Laurent Kremer, Gaurav Bhargava, Parvesh Singh   +10 more
wiley   +1 more source

Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Changes in Primary Angiitis of the Central Nervous System. [PDF]

J Inflamm Res
Lu P, Cui L, Zhang L, Wang H, Yin L, Tian D, Zhang X.   +6 more
europepmc   +1 more source

Targeting ryanodine receptors with allopurinol and xanthine derivatives for the treatment of cardiac and musculoskeletal weakness disorders. [PDF]

Proc Natl Acad Sci U S A
Miotto MC, Luna-Figueroa E, Tchagou C, Bahlouli L, Reiken S, Dridi H, Liu Y, Weninger G, Marks AR.   +8 more
europepmc   +1 more source

Regioselective and Anisotropic Multi‐Patching of Small Microparticles via a Polymer Brush‐Assisted Microcontact Printing (µCP)

Advanced Functional Materials, Volume 35, Issue 24, June 19, 2025.
A method to fabricate anisotropic SiO2 patchy microspheres is presented using a modified microcontact printing technique. This involves a PDMS elastomer stamp with grooved surface topography, creating a confined environment for the microspheres.
Martin Reifarth, Marcel Sperling, Richard Grobe, Pinar Akarsu, Florian Schmitt, Maurice Schmette, Steffen Tank, Katja M. Arndt, Salvatore Chiantia, Matthias Hartlieb, Alexander Böker   +10 more
wiley   +1 more source