Results 231 to 240 of about 601,747 (289)

Uracil nucleotides enhance the degranulation of human basophils induced by anti-IgE antibody via a purinergic receptor (P6016)

Journal of Immunology, 2013
The P2Y receptors (P2YRs) are a family of G protein-coupled purinergic receptors that are stimulated by ATP, ADP, UTP, UDP, and UDP-G, and their interaction induces a wide range of biological effects in various cells through phospholipase C activation,
Manabu Nakano, F. Kudo, Toshiya Nakamura, K. Kasai, Kyoko Ito, H. Takami, Koichi Ito   +6 more
semanticscholar   +1 more source

Potential signalling roles for UTP and UDP: sources, regulation and release of uracil nucleotides.

Trends in Pharmacological Sciences, 1997
Increasing evidence for receptors for uracil nucleotides has focused interest on specific signalling mechanisms involving UTP and UDP. At least three metabotropic P2 receptors are stimulated by uracil nucleotides with equal or greater potency than by adenine nucleotides, and there might be ionotropic receptors as well.
C. Anderson, F. Parkinson
semanticscholar   +3 more sources

Recognition of an Unnatural Difluorophenyl Nucleotide by Uracil DNA Glycosylase

Biochemistry, 2004
The DNA repair enzyme uracil DNA glycosylase (UDG) utilizes base flipping to recognize and remove unwanted uracil bases from the genome but does not react with its structural congener, thymine, which differs by a single methyl group. Two factors that determine whether an enzyme flips a base from the duplex are its shape and hydrogen bonding properties.
Yu Lin, Jiang, Lynda M, McDowell, Barbara, Poliks, Daniel R, Studelska, Chunyang, Cao, Gregory S, Potter, Jacob, Schaefer, Fenhong, Song, James T, Stivers   +8 more
openaire   +2 more sources

Palladium-catalyzed coupling reactions of uracil nucleosides and nucleotides

Journal of the American Chemical Society, 1980
C. Bigge, P. Kalaritis, J. Deck, M. Mertes   +3 more
semanticscholar   +2 more sources

Glomerular uracil nucleotide synthesis: effects of diabetes and protein intake

American Journal of Physiology-Renal Physiology, 1988
The biosynthesis of uridine 5'-triphosphate (UTP), uridine 5'-diphosphohexoses, and 5'-diphosphohexosamines (UDP-sugars) was studied in isolated rat glomeruli 48 h after streptozotocin-induced diabetes. Compared with control, diabetic glomeruli demonstrated an increase in the following: exogenous orotate utilization, orotate incorporation into UTP and
P, Cortes, F, Dumler, D L, Paielli, N W, Levin   +3 more
openaire   +2 more sources

Nucleotide mimicry in the crystal structure of the uracil-DNA glycosylase–uracil glycosylase inhibitor protein complex

Nature Structural & Molecular Biology, 1995
The Bacillus subtilis bacteriophages PBS-1 and PBS-2 protect their uracil-containing DNA by expressing an inhibitor protein (UGI) which inactivates the host uracil-DNA glycosylase (UDGase) base-excision repair enzyme. Also, PBS1/2 UGI efficiently inactivates UDGases from other biological sources, including the enzyme from herpes simplex virus type-1 ...
R, Savva, L H, Pearl
openaire   +2 more sources

Stimulation of mouse cultured sympathetic neurons by uracil but not adenine nucleotides

Neuroscience, 2001
Cultured neurons from the paravertebral sympathetic chain of rats possess excitatory P2X as well as excitatory uracil nucleotide-sensitive P2Y receptors. Preliminary observations had indicated that the analogous neurons of mice lacked P2X receptors. This difference was now investigated.
W. Nörenberg, I. Göbel, A. Meyer, S. Cox, K. Starke, A. Trendelenburg   +5 more
semanticscholar   +4 more sources

Synthesis of 5-styryl derivatives of uracil nucleosides and nucleotides.

Tetrahedron Letters, 1979
Abstract Uracil nucleosides and nucleotides undergo a palladium catalyzed coupling reaction with styrenes to yield the respective 5-substituted derivatives.
Christopher F Bigge, Panos Kalaritis, Mathias P Mertes   +2 more
openaire   +1 more source

Titania-based photocatalytic degradation of two nucleotide bases, cytosine and uracil

Applied Catalysis A: General, 2014
Abstract The photocatalytic degradation of two components of DNA and RNA, cytosine (C4H5N3O) and uracil (C4H4N2O2) differing only by the presence of an amine or a carbonyl group was investigated in the presence of UV-irradiated TiO2 aqueous suspensions.
L. Elsellami, K. Sahel, F. Dappozze, S. Horikoshi, A. Houas, C. Guillard   +5 more
openaire   +1 more source

Some new derivatives of Ni(II) with uracil, uridine and nucleotides

Inorganica Chimica Acta, 1986
Abstract This paper describes the synthesis of compounds of Ni(II) with uracil, uridine and the nucleotides 5′UMP, 5′CMP, 5′GMP and 5′IMP, and their characterization, carried out by elemental analysis, by studying the infrared spectra, diffuse reflectance and conductivity measurement.
Juan J. Fiol, Angel Terron, Virtudes Moreno   +2 more
openaire   +1 more source