Results 91 to 100 of about 14,896 (211)

Exercise and hyperuricemia: an opinion article

Annals of Medicine
Hyperuricaemia (HUA) is an abnormally high concentration of serum urate caused by either an excess of uric acid production or decreased excretion capacity in the body.
Ting Zhang, Wei Liu, Song Gao
doaj   +1 more source

اثر راسبوريکيس وآلوپورينول در پيشگيری و درمان بيماران مبتلا به هيپراوريسمی ناشی از سندروم ليز تومور در کودکان مبتلا به لوسمی و لنفوم در بيمارستان کودکان حضرت علی اصغر(ع): مطالعه کوهورت [PDF]

, 2010
زمينه و هدف: سندروم ليز تومور عبارت است از آزادی مواد داخل سلولی به درون جريان خون به طور خود بخودی و يا به دنبال درمان ضد سرطان که با هيپراوريسمی، هيپر کالمی، هيپرفسفاتمی و هيپوکلسمی خود را نشان می‌دهد.
ارجمندی رفسنجانی, خدیجه, تشويقی, مریم, تقی‌پور, رضا   +2 more
core  

Gout - a guide for the general and acute physicians. [PDF]

, 2017
Gout is the most prevalent inflammatory arthritis and affects 2.5% of the general population in the UK. It is also the only arthritis that has the potential to be cured with safe, inexpensive and well tolerated urate-lowering treatments, which reduce ...
Abhishek, A, Doherty, M, Roddy, E
core   +1 more source

Update on hyperuricaemia and gout with evidence based management guidelines

South African Family Practice, 2015
Gout is now the leading cause of inflammatory arthritis, affecting 1–2% of the population. The metabolic syndrome, cardiovascular risk factors, cardiovascular events and mortality are more common with gout.
Girish M. Mody
doaj   +1 more source

The genetics of cardiovascular disease [PDF]

, 2008
Recent advances in genotyping technology and insights into disease mechanisms have increased interest in the genetics of cardiovascular disease. Several candidate genes involved in cardiovascular diseases were identified from studies using animal models,
Abu-Amero, Aitman, Anna F. Dominiczak, Benhamou, Bhatnagar, Bowcock, Caulfield, Chen, Christian Delles, Clark, Conrad, Cowley, Cupples, Delles, Delles, Delles, Dominiczak, Dominiczak, Dutil, Edwards, Emilsson, Garrett, Good, Graham, Grunfeld, Gunderson, Guzik, Hamilton, Hamilton, Harrap, Hunt, Iwai, Jakubowska, Jeffs, Jeffs, Ji, Kathiresan, Kerr, Klein, Latronico, Levy, Martin W. McBride, Matarín, Matarín, Matsuzaki, McBride, McBride, McCarthy, Monti, Moreno, Mueller, Newhouse, Oniki, Padmanabhan, Padmanabhan, Petretto, Pollex, Rapp, Roodi, Samani, Sandhu, Sandosh Padmanabhan, Sayed-Tabatabaei, Sharma, Staessen, Teo, Tobin, Tobin, Turner, Wallace, Wilson, Zalba, Zimmerli   +72 more
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Tophaceous gout

Clinical Case Reports
Key Clinical Message Hyperuricemic patients (≥7.8 mg/dL) can develop polyarticular tophaceous gout from intermittent arthritis if untreated. Acute flares and tophi development can be avoided by lowering blood urate levels with xanthine oxidase inhibitors.
Durga Neupane, Nimesh Lageju, Lokesh Shekher Jaiswal, Narendra Pandit, Asim Mahat, Saransh Ghimire, Upendra Pokhrel, Sefali Koirala   +7 more
doaj   +1 more source

In vivo study of newly developed albumin-conjugated urate oxidase for gout treatment. [PDF]

Arthritis Res Ther, 2023
Cho J, Yang B, Lee JH, Kim H, Kim H, Go EB, Bak DH, Park SJ, Kwon I, Choi JI, Lee K.   +10 more
europepmc   +1 more source

Guidelines for the treatment of gout: a Swiss perspective. [PDF]

, 2016
Gout is a common condition and its management is suboptimal. A number of guidelines on the management of gout have been published in the last decade by professional societies with the aim of informing the physician of the recommended therapeutic ...
Alromaih, F., So, A., Wüthrich, H.
core   +1 more source

The last defence? Surgical aspects of gouty arthritis of hand and wrist [PDF]

, 2011
OBJECTIVE: To review the epidemiology, pathophysiology, clinical manifestations, diagnosis, and treatment of gouty arthritis of the hand and wrist, with a focus on the surgical aspects. DATA SOURCES AND EXTRACTION: Electronic databases including MEDLINE,
Fung, BKK, Tang, CKY
core  

Microbial Uricase and its Unique Potential Applications

Postępy Mikrobiologii
The uricase enzyme yields allantoin, hydrogen peroxide, and carbon dioxide by catalyzing the oxidative opening of the purine ring in the urate pathway. This enzyme is important for biochemical diagnosis and reduces toxic urate accumulation during various
Elbanna Khaled, Alshareef Atheer, Neyaz Leena A., El-Readi Mahmoud Z., Abulreesh Hussein H.   +4 more
doaj   +1 more source