Battle of the strategies: diet versus drug therapy for gout
Современная ревматологияThe best results in combating gout are achieved through a combination of diet and drug therapy. Urate-lowering therapy, which includes febuxostat, has been shown to be more effective and convenient than diet when it comes to achieving and maintaining ...
O. V. Zhelyabina +2 more
doaj +1 more source
Substrate activation in the urate oxidase reaction [PDF]
The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf ...
Doll, Charles G., 1968-
core +1 more source
Studies on Urate Oxidase of Candida utilis
Agricultural and Biological Chemistry, 1971 Some physical and chemical properties of urate oxidase (EC 1. 7. 3. 3) isolated from the cells of Candida utilis were investigated. The molecular weight was estimated to be 1.2×105 by the equilibrium sedimentation and gel filtration methods. The isoelectric point was determined as 5.4 by the method of density electrofocusing. The enzyme showed a slight
Kimikazu ITAYA +2 more
openaire +2 more sources
PASylated Urate Oxidase Enzyme: Enhancing Biocatalytic Activity, Physicochemical Properties, and Plasma Half-Life. [PDF]
ACS Omega, 2022 Najjari A +3 more
europepmc +1 more source
Immunoenzymology of purified urate oxidase [PDF]
Biochemical Journal, 1971 D A, Fitzpatrick +2 more
openaire +2 more sources
Molecular Elucidation of a Urate Oxidase from Deinococcus radiodurans for Hyperuricemia and Gout Therapy. [PDF]
Int J Mol Sci, 2021 Chiu YC, Hsu TS, Huang CY, Hsu CH.
europepmc +1 more source
The role of urate and xanthine oxidase in vascular oxidative stress: future directions
Therapeutics and Clinical Risk Management, 2009 Jacob George, Allan StruthersDivision of Medicine and Therapeutics, Ninewells Hospital and Medical School, Dundee, UKAbstract: Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction.
Jacob George, Allan Struthers
doaj
mSphereHyperuricemia has become the second most prevalent metabolic disease after diabetes, but the limitations of urate-lowering treatment (ULT) drugs and patient nonadherence make ULT far less successful. Thus, more ULT approaches urgently need to be explored.
Wenxuan Liu +10 more
doaj +1 more source
Fixed-Dose Recombinant Urate Oxidase in the Treatment of Paediatric Tumour Lysis Syndrome: A Regional Cancer Centre Experience. [PDF]
Asian Pac J Cancer Prev, 2021 L A +6 more
europepmc +1 more source
Current issues in the practical use of allopurinol in patients with gout and hyperuricemia
Современная ревматологияThe cornerstone of the treatment of gout and hyperuricemia (HU) is the use of urate-lowering drugs, primarily xanthine oxidase inhibitors. Allopurinol, which has been used to treat gout for six decades, is the first line urate-lowering therapy (ULT ...
M. S. Eliseev
doaj +1 more source