Results 31 to 40 of about 14,896 (211)

Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation. [PDF]

open access: yes, 2015
Activation of the NLRP3 inflammasome by microbial ligands or tissue damage requires intracellular generation of reactive oxygen species (ROS). We present evidence that macrophage secretion of IL1β upon stimulation with ATP, crystals or LPS is mediated by
Busso, N.   +8 more
core   +1 more source

Acute kidney injury in critically ill cancer patients : an update [PDF]

open access: yes, 2016
Patients with cancer represent a growing group among actual ICU admissions (up to 20 %). Due to their increased susceptibility to infectious and noninfectious complications related to the underlying cancer itself or its treatment, these patients ...
Benoit, Dominique   +3 more
core   +2 more sources

Exercise redox biochemistry:conceptual, methodological and technical recommendations [PDF]

open access: yes, 2017
Exercise redox biochemistry is of considerable interest owing to its translational value in health and disease. However, unaddressed conceptual, methodological and technical issues complicate attempts to unravel how exercise alters redox homeostasis in ...
Bailey, Damian M.   +3 more
core   +7 more sources

Antigenic independence of some microbial urate oxidases [PDF]

open access: yesInfection and Immunity, 1975
Antisera were prepared to urate oxidase derived from three microbial species, a yeast (Candida utilis), a mold (Aspergillus flavus), and a bacterium (Bacillus fastidious). The antisera inhibited enyme activity to a limited extent. Cross-reaction studies with preparations of the enzyme from these and other species indicated that the microbial enzyme ...
D A, Fitzpatrick, K F, McGeeney
openaire   +2 more sources

Lactiplantibacillus plantarum enables blood urate control in mice through degradation of nucleosides in gastrointestinal tract

open access: yesMicrobiome, 2023
Background Lactobacillus species in gut microbiota shows great promise in alleviation of metabolic diseases. However, little is known about the molecular mechanism of how Lactobacillus interacts with metabolites in circulation.
Mengfan Li   +8 more
doaj   +1 more source

Progress in Understanding the Mechanism by Which Probiotics Alletivate Hyperuricemia [PDF]

open access: yesShipin Kexue, 2023
Hyperuricemia (HUA) is a disease caused by excessive production and/or inadequate excretion of uric acid (UA) in the body, and persistent HUA can lead to gout.
HUANG Jiahao, LI Xianping, ZHAO Junying, QIAO Weicang, LIU Lu, CHEN Lijun
doaj   +1 more source

Amperometric Uric Acid Biosensor with Improved Analytical Performances Based on Alkaline-Stable H2O2 Transducer

open access: yesInternational Journal of Electrochemical Science, 2012
Electrodes modified with Prussian blue containing structurally incorporated Ni2+ ions were employed as the alkaline-stable H2O2 transducers in amperometric uric acid biosensors based on urate oxidase.
Damir Iveković   +3 more
doaj   +1 more source

Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer [PDF]

open access: yes, 2014
published_or_final_versio
Chan, GCF   +3 more
core   +1 more source

Biosensor measurement of purine release from cerebellar cultures and slices [PDF]

open access: yes, 2010
We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Wall, Mark J.   +2 more
core   +2 more sources

Glut9-mediated Urate Uptake Is Responsible for Its Protective Effects on Dopaminergic Neurons in Parkinson’s Disease Models

open access: yesFrontiers in Molecular Neuroscience, 2018
Considerable evidence has shown that elevated plasma or cerebrospinal fluid (CSF) urate levels correlated with a reduced risk of Parkinson’s disease (PD).
Mingxia Bi   +3 more
doaj   +1 more source

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