Results 51 to 60 of about 1,056,484 (359)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Produção de novilhos de corte com suplementação em pastagem de azevém submetida a doses de nitrogênio Supplementation of beef steers on ryegrass pastures submitted to different nitrogen fertilization

Revista Brasileira de Zootecnia, 2006
O experimento foi realizado em várzea sistematizada com o objetivo de comparar os efeitos do uso de doses de N em cobertura, associadas a níveis de suplementação energética, sobre o desempenho animal e a qualidade e produção de forragem.
Gelson dos Santos Difante, Enio Marchezan, Silvio Carlos Cazarotto Villa, Marta Gomes da Rocha, Fernando Machado dos Santos, Edinalvo Rabaioli Camargo   +5 more
doaj   +1 more source

Studies on the denaturation of antibody: II. The effect of protein concentration on the rate of denaturation of diphtheria antitoxin by urea [PDF]

, 1945
The specific rate of inactivation of antitoxin in urea solutions, as measured by the Römer neutralization test with toxin, has been shown to be independent of the concentration of protein under the conditions studied.
Wright, George G.
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Propileno-glicol ou monensina na dieta de vacas leiteiras no período de transição: saúde do úbere, produção e composição do leite Propylene glycol or monensin on diets of dairy cows during the transition period: udder health, milk yield and composition

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2008
Avaliou-se o efeito do propileno-glicol e da monensina na dieta de vacas leiteiras no período de transição sobre a produção e composição do leite. Foram utilizadas 42 vacas da raça Holandesa com média de produção na lactação anterior de 8.000kg.
R.V. Sá Fortes, M.A.T. Artunduaga, A.U. Carvalho, S.G. Coelho, R.B. Reis, A.M.Q. Lana   +5 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Eficiência nutricional e aproveitamento do nitrogênio pelo capim-marandu de pastagem em estágio moderado de degradação sob doses e fontes de nitrogênio Nutritional efficiency and nitrogen uptake by capim-marandu at pasture in moderate stage of degradation under doses and sources of nitrogen

Ciência e Agrotecnologia, 2011
O presente estudo foi desenvolvido sob condições de campo, visando avaliar a eficiência no uso e no aproveitamento do nitrogênio pelo capim-marandu por meio de diversos índices.
Douglas Ramos Guelfi Silva, Kátia Aparecida de Pinho Costa, Valdemar Faquin, Itamar Pereira de Oliveira, Milena Rízzia Ferreira de Souza, Marcos André Silva Souza   +5 more
doaj   +1 more source

A novel approach for the production of nitrogen doped TiO2 nanoparticles [PDF]

, 2015
In this study a visible light active nitrogen doped nanostructure titanium dioxide was synthesized by a simple mixing of Degussa P25 and Urea powder and further thermal treatment under the adequate conditions.
BRAVI, Marco, CHIANESE, Angelo, RUZMANOVA, YANA, STOLLER, Marco   +3 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Proteína degradável no rúmen na dieta de bovinos: digestibilidades total e parcial dos nutrientes e parâmetros ruminais Rumen degradable protein on bovine diet: total and partial nutrient digestibility and ruminal parameters

Revista Brasileira de Zootecnia, 2008
Quatro novilhos da raça Holandesa (450 kg) portadores de cânula ruminal e duodenal, recebendo dietas com níveis de proteína degradável no rúmen (PDR) de 50, 60, 65 e 70%, associadas a uma fonte de amido de alta degradabilidade ruminal (farinha de ...
Saul Ferreira Caldas Neto, Lucia Maria Zeoula, Ivanor Nunes do Prado, Antonio Ferriani Branco, Ricardo Kazama, Luiz Juliano Valério Geron, Emilyn Midori Maeda, Fernanda Fereli   +7 more
doaj   +1 more source