Results 81 to 90 of about 23,457 (249)

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

Advanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim, In Ah Kwon, Bo Seop Jeong, Hyo Seon Kim, Joo‐Hwan Park, Sung Jean Park, Sang‐Rae Lee, Youngki Lee, Dongwoo Khang   +8 more
wiley   +1 more source

The burden of pharmacological treatment on health-related quality of life in people with a urea cycle disorder: a qualitative study. [PDF]

J Patient Rep Outcomes, 2021
Yeowell G, Burns DS, Fatoye F.
europepmc   +1 more source

Diagnosis of Urea Cycle Disorders [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1977
T, Palmer, V G, Oberholzer
openaire   +2 more sources

Prospective treatment of urea cycle disorders

The Journal of Pediatrics, 1991
We present a diagnostic and therapeutic protocol designed to prevent clinical expression of inborn errors of urea synthesis in the neonatal period, and discuss the long-term developmental outcome of survivors. The families of 32 infants, among 43 identified prenatally as being at risk for a urea cycle disorder, chose to have their infants treated ...
N E, Maestri, E R, Hauser, D, Bartholomew, S W, Brusilow   +3 more
openaire   +2 more sources

Unconstrained Coordination of Pt Single Atoms on Distorted g‐C3N4 Enables Electronic Flexibility and Enhanced Microplastics Photoreforming

Advanced Science, EarlyView.
This study reveals Pt single atoms anchored on distorted graphitic carbon nitride, exhibiting flexible coordination and enhanced interfacial charge transfer. Combined spectroscopy and DFT reveal asymmetric Pt─N environments that promote photoreforming of microplastics into hydrogen, demonstrating a solar‐driven pathway for plastic upcycling with ...
Ting‐Han Lin, Yin‐Hsuan Chang, Jia‐Mao Chang, Ciao‐Yun Huang, Kai‐Chi Hsiao, Kuo‐Ping Chiang, Ying‐Han Liao, Kai‐Hsiang Hsu, Jen‐Fu Hsu, Ming‐Chung Wu   +9 more
wiley   +1 more source

Profile of sodium phenylbutyrate granules for the treatment of urea-cycle disorders: patient perspectives

Patient Preference and Adherence, 2017
Luis Peña-Quintana,1–3 Marta Llarena,2 Desiderio Reyes-Suárez,2 Luis Aldámiz-Echevarria4 1Pediatric Gastroenterology, Hepatology, and Nutrition Unit, Universitario Materno-Infantil Hospital de Canarias, University of Las ...
Peña-Quintana L, Llarena M, Reyes-Suárez D, Aldámiz-Echevarria L   +3 more
doaj  

A Case with Autism Spectrum Disorder and Concomitant Arginase Deficiency

Journal of Behçet Uz Children's Hospital
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by lack of social interaction, limited areas of interest, and repetitive behaviors.
Rabia Eren, Buket Canlan Özaydın, Emine Göksoy, Zehra Manav Yiğit, Börte Gürbüz Özgür   +4 more
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Is there any relationship between mutation in CPS1 Gene and pregnancy loss?

International Journal of Reproductive BioMedicine, 2019
Background Carbamoyl phosphate synthetase 1 (CPS1) is a liver-specific enzyme with the lowest enzymatic rate, which determines the overall rate of the other reactions in the pathway that converts ammonia to carbamoyl phosphate in the first step of ...
Mehrdad Talebi, Mohammad Yahya Vahidi Mehrjardi, Kambiz Kalhor, Mohammadreza Dehghani   +3 more
doaj   +1 more source

One‐Step Preparation of Lanthanide‐Doped Polyurea Multicolor Microspheres for Versatile Fluorescent Applications

Advanced Science, EarlyView.
Lanthanide‐doped polyurea microspheres are prepared via a facile one‐step precipitation polymerization. They exhibit strong hydrogen‐bonding and coordination interactions with excellent properties, including multicolor emission, high quantum yield (75.3%), remarkable stability, redispersibility, and biocompatibility.
Guiyu Zhang, Xiaoxia Yu, Xinhui Wang, Xiang Zheng Kong, Xiangling Gu, Jitao Liu, Shusheng Li, Xiaoli Zhu, Lianbao Cao, Xubao Jiang   +9 more
wiley   +1 more source